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Details:
The collaboration aims for the commercialisation of novel antibacterial drug Xacduro (sulbactam-durlobactam) for the treatment of carbapenem-resistant Acinetobacter baumannii, in mainland China.
Lead Product(s): Sulbactam,Durlobactam
Therapeutic Area: Infections and Infectious Diseases Brand Name: Xacduro
Study Phase: ApprovedProduct Type: Small molecule
Recipient: Zai Lab
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration November 21, 2024
Lead Product(s) : Sulbactam,Durlobactam
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Recipient : Zai Lab
Deal Size : Undisclosed
Deal Type : Collaboration
Zai Lab and Pfizer Collaborate on XACDURO® for Novel Antibacterial Applications
Details : The collaboration aims for the commercialisation of novel antibacterial drug Xacduro (sulbactam-durlobactam) for the treatment of carbapenem-resistant Acinetobacter baumannii, in mainland China.
Brand Name : Xacduro
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 21, 2024
Details:
Hympavzi (marstacimab) is a human mAb IgG1 that targets TFPI approved as a subcutaneous treatment for severe hemophilia A or moderately severe to severe hemophilia B in 12 years and above patients.
Lead Product(s): Marstacimab
Therapeutic Area: Genetic Disease Brand Name: Hympavzi
Study Phase: ApprovedProduct Type: Large molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable November 20, 2024
Lead Product(s) : Marstacimab
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
EU Approves Pfizer’s HYMPAVZI™ for Severe Hemophilia A/B Without Inhibitors
Details : Hympavzi (marstacimab) is a human mAb IgG1 that targets TFPI approved as a subcutaneous treatment for severe hemophilia A or moderately severe to severe hemophilia B in 12 years and above patients.
Brand Name : Hympavzi
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 20, 2024
Details:
The collaboration aims to discover novel molecular glue degraders for multiple targets in several disease areas, including oncology.
Lead Product(s): Undisclosed
Therapeutic Area: Oncology Brand Name: Undisclosed
Study Phase: Discovery PlatformProduct Type: Small molecule
Recipient: TRIANA Biomedicines
Deal Size: $1,549.0 million Upfront Cash: $49.0 million
Deal Type: Collaboration October 15, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Recipient : TRIANA Biomedicines
Deal Size : $1,549.0 million
Deal Type : Collaboration
TRIANA and Pfizer Partner to Discover Novel Molecular Glue Degraders
Details : The collaboration aims to discover novel molecular glue degraders for multiple targets in several disease areas, including oncology.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : $49.0 million
October 15, 2024
Details:
IsomAb collaborates with Pfizer Ignite to support preclinical development and IND-enabling studies for ISM-001 for the treatemnt of chronic limb threatening ischaemia.
Lead Product(s): ISM-001
Therapeutic Area: Cardiology/Vascular Diseases Brand Name: ISM-001
Study Phase: PreclinicalProduct Type: Large molecule
Recipient: IsomAb
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Collaboration October 15, 2024
Lead Product(s) : ISM-001
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Preclinical
Recipient : IsomAb
Deal Size : Undisclosed
Deal Type : Collaboration
IsomAb and Pfizer Partner on PAD Development Candidate Collaboration
Details : IsomAb collaborates with Pfizer Ignite to support preclinical development and IND-enabling studies for ISM-001 for the treatemnt of chronic limb threatening ischaemia.
Brand Name : ISM-001
Molecule Type : Large molecule
Upfront Cash : Undisclosed
October 15, 2024
Details:
Hympavzi (marstacimab) is a human mAb IgG1 that targets TFPI approved as a subcutaneous treatment for severe hemophilia A or moderately severe to severe hemophilia B in 12 years and above patients.
Lead Product(s): Marstacimab
Therapeutic Area: Genetic Disease Brand Name: Hympavzi
Study Phase: ApprovedProduct Type: Large molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable October 11, 2024
Lead Product(s) : Marstacimab
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
FDA Approves Pfizer’s HYMPAVZI™ For Hemophilia A Or B Without Inhibitors
Details : Hympavzi (marstacimab) is a human mAb IgG1 that targets TFPI approved as a subcutaneous treatment for severe hemophilia A or moderately severe to severe hemophilia B in 12 years and above patients.
Brand Name : Hympavzi
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 11, 2024
Details:
Cresemba (isavuconazonium sulfate) is the prodrug of isavuconazole which is an azole antifungal indicated for the treatment of invasive aspergillosis and invasive mucormycosis.
Lead Product(s): Isavuconazonium Sulfate
Therapeutic Area: Infections and Infectious Diseases Brand Name: Cresemba
Study Phase: ApprovedProduct Type: Small molecule
Recipient: Basilea Pharmaceutica
Deal Size: Undisclosed Upfront Cash: Undisclosed
Deal Type: Licensing Agreement October 10, 2024
Lead Product(s) : Isavuconazonium Sulfate
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Approved
Recipient : Basilea Pharmaceutica
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Strong Cresemba® Sales in Asia Trigger Milestone Payment to Basilea
Details : Cresemba (isavuconazonium sulfate) is the prodrug of isavuconazole which is an azole antifungal indicated for the treatment of invasive aspergillosis and invasive mucormycosis.
Brand Name : Cresemba
Molecule Type : Small molecule
Upfront Cash : Undisclosed
October 10, 2024
Details:
BHV-2100 is a potentially first-in-class, potent, selective, orally administered TRPM3 antagonist, a novel, non-sedating non-opioid treatment for migraine and pain.
Lead Product(s): BHV-2100
Therapeutic Area: Neurology Brand Name: BHV-2100
Study Phase: Phase IIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 30, 2024
Biohaven Initiates Pivotal Trial of Novel Investigational Drug For Treatment of Migraine
Details : BHV-2100 is a potentially first-in-class, potent, selective, orally administered TRPM3 antagonist, a novel, non-sedating non-opioid treatment for migraine and pain.
Brand Name : BHV-2100
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 30, 2024
Details:
Padcev (enfortumab vedotin), a nectin-4 inhibitor ADC in combination with keytruda, a PD-1 inhibitor. It is being evaluated for the treatment of locally advanced or metastatic urothelial cancer.
Lead Product(s): Enfortumab Vedotin,Pembrolizumab
Therapeutic Area: Oncology Brand Name: Padcev
Study Phase: ApprovedProduct Type: Large molecule
Recipient: Astellas Pharma
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 24, 2024
Lead Product(s) : Enfortumab Vedotin,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Approved
Recipient : Astellas Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Japan Approves PADCEV™ with KEYTRUDA® for Unresectable Urothelial Carcinoma
Details : Padcev (enfortumab vedotin), a nectin-4 inhibitor ADC in combination with keytruda, a PD-1 inhibitor. It is being evaluated for the treatment of locally advanced or metastatic urothelial cancer.
Brand Name : Padcev
Molecule Type : Large molecule
Upfront Cash : Not Applicable
September 24, 2024
Details:
BHV-4157 (troriluzole ) is a third-generation novel prodrug that modulates glutamate, the most abundant excitatory neurotransmitter in the human body. It is being evaluated for Spinocerebellar Ataxia.
Lead Product(s): Troriluzole
Therapeutic Area: Genetic Disease Brand Name: BHV-4157
Study Phase: Phase IIIProduct Type: Small molecule
Sponsor: Not Applicable
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 23, 2024
Lead Product(s) : Troriluzole
Therapeutic Area : Genetic Disease
Highest Development Status : Phase III
Partner/Sponsor/Collaborator : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Biohaven Reports Positive Results for Troriluzole in Spinocerebellar Ataxia
Details : BHV-4157 (troriluzole ) is a third-generation novel prodrug that modulates glutamate, the most abundant excitatory neurotransmitter in the human body. It is being evaluated for Spinocerebellar Ataxia.
Brand Name : BHV-4157
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 23, 2024
Details:
VLA15, an alum-adjuvanted intramuscular vaccine, which is currently undergoing clinical development for the treatment of Lyme disease.
Lead Product(s): VLA15
Therapeutic Area: Infections and Infectious Diseases Brand Name: VLA15
Study Phase: Phase IIIProduct Type: Vaccine
Recipient: Valneva
Deal Size: Not Applicable Upfront Cash: Not Applicable
Deal Type: Not Applicable September 03, 2024
Lead Product(s) : VLA15
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Recipient : Valneva
Deal Size : Not Applicable
Deal Type : Not Applicable
Valneva and Pfizer Report Positive Phase 2 Booster Results for Lyme Disease Vaccine
Details : VLA15, an alum-adjuvanted intramuscular vaccine, which is currently undergoing clinical development for the treatment of Lyme disease.
Brand Name : VLA15
Molecule Type : Vaccine
Upfront Cash : Not Applicable
September 03, 2024
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