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1. Tetralin
1. Tetralin
2. 119-64-2
3. Benzocyclohexane
4. Tetrahydronaphthalene
5. Bacticin
6. Tetraline
7. Tetranap
8. Naphthalene, 1,2,3,4-tetrahydro-
9. Tetralina
10. Naphthalene, Tetrahydro-
11. Naphthalene 1,2,3,4-tetrahydride
12. Tetralene
13. Nsc 77451
14. (c4-c5) Alkyltetrahydronaphthalenes
15. Ft6xmi58yq
16. Naphthalene, 1,2,3,4-tetrahydro-, C1-4-alkyl Derivs.
17. Chebi:35008
18. 1,2,3,4-tetrahydro-naphthalene
19. Nsc-77451
20. Dsstox_cid_6118
21. Dsstox_rid_78023
22. Dsstox_gsid_26118
23. 68412-24-8
24. Tetralina [polish]
25. Caswell No. 842a
26. Cas-119-64-2
27. Ccris 3564
28. Hsdb 127
29. Delta(sup 5,7,9)-naphthantriene
30. Einecs 204-340-2
31. Unii-ft6xmi58yq
32. 1,2,3,4-tetrahydronaphthalene, Reagent Grade, >=97%
33. Epa Pesticide Chemical Code 055901
34. Ai3-01257
35. Tetralin Solvent
36. Einecs 270-178-4
37. Mfcd00001733
38. Tetralin [hsdb]
39. Tetralin [mi]
40. Bmse000530
41. Tetralin [usp-rs]
42. Tetralin [who-dd]
43. Ec 204-340-2
44. Nciopen2_000650
45. 1,3,4-tetrahydronaphthalene
46. 1,2,3,4-tetrahydronapthalene
47. 5,6,7,8-tetrahydronaphthalene
48. Chembl1575635
49. Dtxsid1026118
50. Naphthalene 1,3,4-tetrahydride
51. Wln: L66 & Tj
52. 1,2,3,4 Tetrahyclronaphthalene
53. .delta.(5,7,9)-naphthantriene
54. .delta.(sup 5,9)-naphthantriene
55. Naphthalene-1,2,3,4-tetrahydride
56. Nsc77451
57. Zinc8437660
58. Tox21_201793
59. Tox21_303325
60. Stl264224
61. .delta.(sup 5,7,9)-naphthantriene
62. Akos000121383
63. Ncgc00091744-01
64. Ncgc00091744-02
65. Ncgc00256948-01
66. Ncgc00259342-01
67. Ft-0654145
68. T0107
69. T0713
70. 1,2,3,4-tetrahydronaphthalene, Tetralin, Thn
71. 1,2,3,4-tetrahydronaphthalene, Anhydrous, 99%
72. Q420416
73. 1,2,3,4-tetrahydronaphthalene, Analytical Standard
74. W-108503
75. 1,2,3,4-tetrahydronaphthalene, Reagentplus(r), 99%
76. F1908-0164
77. 1,2,3,4-tetrahydronaphthalene, Vetec(tm) Reagent Grade, 98%
Molecular Weight | 132.20 g/mol |
---|---|
Molecular Formula | C10H12 |
XLogP3 | 3.5 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 0 |
Rotatable Bond Count | 0 |
Exact Mass | 132.093900383 g/mol |
Monoisotopic Mass | 132.093900383 g/mol |
Topological Polar Surface Area | 0 Ų |
Heavy Atom Count | 10 |
Formal Charge | 0 |
Complexity | 92.6 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
ABSORBED VAPOR IS EXCRETED BY KIDNEYS AS ALPHA- AND BETA-TETRAHYDRONAPHTHOLS ANDTHEIR GLUCURONIDES ... .
Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-153
RADIOACTIVE TETRALIN, WHEN ADMIN TO RABBIT, WAS EXCRETED IN URINE AS GLUCURONIDEAT 87-99% AND IN FECES AT 0.6-1.8% OF ORIGINAL DOSE. ... WAS ABSORBED BY MUSSEL BUT NOT METABOLIZED; ... UP TO 80% WAS RELEASED IN UNCHANGED FORM WHEN THE ORGANISM WAS TRANSFERRED TO FRESH SEAWATER.
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 3242
When radioactive tetralin was fed to rabbits, 87-90% of the activity was excreted in the urine in 2 days and 0.5-3.7% on the third day. The feces contained only 0.6-1.8%. No radioactivity was found in the breath, and negligible amounts were retained in the tissues. About 90-99% of the dose was accounted for.
Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 2. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 643
(1-(14)C)-TETRALIN IS METABOLIZED IN RABBITS BY HYDROXYLATION OF ALICYCLIC RING TO YIELD CONJUGATES OF AC-ALPHA-TETRALOL (60% OF DOSE), AC-BETA-TETRALOL (20%) & TETRALIN-1,2-DIOL (2.5%), & HYDROXYLATION OF AROMATIC RING ... YIELDING AR-BETA-TETRALOL (5,6,7,8-TETRAHYDRO-2-NAPHTHOL, 0.1%).
Parke, D. V. The Biochemistry of Foreign Compounds. Oxford: Pergamon Press, 1968., p. 220
YIELDS 2-HYDROXYTETRALYLMERCAPTURIC ACID, 1,2,3,4-TETRAHYDRO-1-NAPHTHOL, 1,2,3,4-TETRAHYDRO-2-NAPHTHOL IN RABBIT. YIELDS 1,2,3,4-TETRAHYDRO-1,2-DIHYDROXYNAPHTHALENE, 5,6,7,8-TETRAHYDRO-2-NAPHTHOL IN RABBIT. /FROM TABLE/
Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. T-10
In rabbits, the main urinary metabolite was the glucuronide of alpha-tetralol (52.4%). Other conjugated metabolites were beta-tetralol (25.3%), 4-hydroxy-alpha-tetralone (6.1%), and cis-tetralin-1,2-diol (0.4%). Using rat liver homogenates, it was shown that conversion of tetralin to tetralol requires reduced nicotinamide adenine dinucleotide phosphate and that tetralin hydroperoxide is a probable intermediate. Further study confirmed this possibility and indicated that tetralin hydroxylation proceeds via a radical mechanism similar to that of lipid peroxidation.
Hayes, W.J., Jr., E.R. Laws, Jr., (eds.). Handbook of Pesticide Toxicology. Volume 2. Classes of Pesticides. New York, NY: Academic Press, Inc., 1991., p. 643
Tetralin, a component of fuels, solvents, and varnishes, is metabolized in male Fischer 344 rats to 1-tetralol, 2-tetralol, 2-hydroxyl-1-tetralone, 4-hydroxyl-1-tetralone, 1,2-tetralindiol, and 1,4-tetralindiol.
PMID:2926829 Serve MP et al; J Toxicol Environ Health 26 (3): 267-75 (1989)
ABOUT THIS PAGE
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PharmaCompass offers a list of 1,2,3,4-Tetrahydronaphthalene API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right 1,2,3,4-Tetrahydronaphthalene manufacturer or 1,2,3,4-Tetrahydronaphthalene supplier for your needs.
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A 1,2,3,4-Tetrahydronaphthalene manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 1,2,3,4-Tetrahydronaphthalene, including repackagers and relabelers. The FDA regulates 1,2,3,4-Tetrahydronaphthalene manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 1,2,3,4-Tetrahydronaphthalene API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A 1,2,3,4-Tetrahydronaphthalene supplier is an individual or a company that provides 1,2,3,4-Tetrahydronaphthalene active pharmaceutical ingredient (API) or 1,2,3,4-Tetrahydronaphthalene finished formulations upon request. The 1,2,3,4-Tetrahydronaphthalene suppliers may include 1,2,3,4-Tetrahydronaphthalene API manufacturers, exporters, distributors and traders.
1,2,3,4-Tetrahydronaphthalene Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of 1,2,3,4-Tetrahydronaphthalene GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 1,2,3,4-Tetrahydronaphthalene GMP manufacturer or 1,2,3,4-Tetrahydronaphthalene GMP API supplier for your needs.
A 1,2,3,4-Tetrahydronaphthalene CoA (Certificate of Analysis) is a formal document that attests to 1,2,3,4-Tetrahydronaphthalene's compliance with 1,2,3,4-Tetrahydronaphthalene specifications and serves as a tool for batch-level quality control.
1,2,3,4-Tetrahydronaphthalene CoA mostly includes findings from lab analyses of a specific batch. For each 1,2,3,4-Tetrahydronaphthalene CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
1,2,3,4-Tetrahydronaphthalene may be tested according to a variety of international standards, such as European Pharmacopoeia (1,2,3,4-Tetrahydronaphthalene EP), 1,2,3,4-Tetrahydronaphthalene JP (Japanese Pharmacopeia) and the US Pharmacopoeia (1,2,3,4-Tetrahydronaphthalene USP).