Find 1,2-Dichlorotetrafluoroethane manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 1,2-dichlorotetrafluoroethane, 1,2-dichloro-1,1,2,2-tetrafluoroethane, Cryofluorane, 76-14-2, Cfc-114, Refrigerant 114
Molecular Formula
C2Cl2F4
Molecular Weight
170.92  g/mol
InChI Key
DDMOUSALMHHKOS-UHFFFAOYSA-N
FDA UNII
6B5VVT93AR

1,2-Dichlorotetrafluoroethane
1 2D Structure

1,2-Dichlorotetrafluoroethane

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1,2-dichloro-1,1,2,2-tetrafluoroethane
2.1.2 InChI
InChI=1S/C2Cl2F4/c3-1(5,6)2(4,7)8
2.1.3 InChI Key
DDMOUSALMHHKOS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C(C(F)(F)Cl)(F)(F)Cl
2.2 Other Identifiers
2.2.1 UNII
6B5VVT93AR
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,2-dichloro-1,1,2,2-tetrafluoroethane

2. 1,2-dichlorotetrafluoroethane

3. Cfc 114

4. Cfc-114

5. Cryofluorane

6. Fluorocarbon 114

7. Freon 114

8. Frigiderm

2.3.2 Depositor-Supplied Synonyms

1. 1,2-dichlorotetrafluoroethane

2. 1,2-dichloro-1,1,2,2-tetrafluoroethane

3. Cryofluorane

4. 76-14-2

5. Cfc-114

6. Refrigerant 114

7. Frigiderm

8. Freon 114

9. Halocarbon 114

10. Propellant 114

11. Fluorocarbon 114

12. Fluorane 114

13. Genetron 114

14. Genetron 316

15. Arcton 33

16. Arcton 114

17. Frigen 114

18. Ledon 114

19. F 114 (halocarbon)

20. R 114 (halocarbon)

21. Ucon 114

22. Ethane, 1,2-dichloro-1,1,2,2-tetrafluoro-

23. Sym-dichlorotetrafluoroethane

24. Cryofluorane [inn]

25. Cryfluorane

26. Fkw 114

27. Ethane, 1,2-dichlorotetrafluoro-

28. Fc 114

29. Tetrafluordichlorethan

30. Cryofluorane (inn)

31. 1,1,2,2-tetrafluoro-1,2-dichloroethane

32. Chlorofluorocarbon 114

33. F 114

34. R 114

35. Nsc-760428

36. 6b5vvt93ar

37. Dichlorotetrafluoroethane [nf]

38. 76-14-21320-37-2(mixedisomers)

39. P-114

40. Dichlorotetrafluoroethane (nf)

41. Cryofluoranum [latin]

42. Caswell No. 326a

43. Criofluorano

44. Cryofluoranum

45. Cryoflurane

46. Cryofluoranum [inn-latin]

47. Criofluorano [inn-spanish]

48. Ccris 8973

49. Hsdb 146

50. Cfc 114

51. Einecs 200-937-7

52. Unii-6b5vvt93ar

53. Epa Pesticide Chemical Code 326200

54. Brn 1740333

55. Cryofluoran

56. Refrigerant R114

57. Isotron 114

58. Cclf2cclf2

59. Dichlortetrafluoroethane

60. Halon 242

61. Flon-114

62. Cryofluorane [mi]

63. S-dichlorotetrafluoroethane

64. Schembl865

65. (cf2cl)2

66. Cryofluorane [mart.]

67. 4-01-00-00137 (beilstein Handbook Reference)

68. Chembl325436

69. Dtxsid8026434

70. Hms3264g16

71. Pharmakon1600-01502370

72. Zinc8214542

73. Dichloro-1,1,2,2-tetrafluoroethane

74. Mfcd00000778

75. Nsc760428

76. Dichlorotetrafluoroethane [ii]

77. 1,2-dichlorotetrafluoro-ethane

78. Akos015915972

79. Ccg-213721

80. Dichlorotetrafluoroethane [hsdb]

81. Nsc 760428

82. Tetrafluordichlorethan [who-dd]

83. Dichlorotetrafluoroethane [vandf]

84. 1,2-dichlorotetrafluoroethane, >=99.5%

85. Db-056030

86. D0417

87. Ft-0606367

88. D03790

89. Ab01563180_01

90. Q420380

91. Sr-01000944235

92. Sr-01000944235-1

93. 1,2-dichlorotetrafluoroethane 100 Microg/ml In Methanol

94. 1,2-dichlorotetrafluoroethane (cfc-114) 2000 Microg/ml In Methanol

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 170.92 g/mol
Molecular Formula C2Cl2F4
XLogP32.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass169.9313180 g/mol
Monoisotopic Mass169.9313180 g/mol
Topological Polar Surface Area0 Ų
Heavy Atom Count8
Formal Charge0
Complexity78
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Therapeutic Uses

In various "skin freezes" alone or with other agents by aerosol application. Recommended for spraying of snake & insect bites to retard absorption of venom. /Former/

Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 165


5 Pharmacology and Biochemistry
5.1 Absorption, Distribution and Excretion

Human and animal studies indicate rapid excretion of inhaled CFC-114. In a study with radiolabeled CFC-114, 30 minute retention of the dose inhaled in a single breath was 12% versus 23%, 10%, and 20% for comparable doses of trichlorofluoromethane (CFC-11), dichlorodifluoro-methane (CFC-12), and trifluorotrichloroethane (CFC-113), respectively.

American Conference of Governmental Industrial Hygienists. Documentation of the TLV's and BEI's 7th Edition. Dichlorotetrafluoroethane p. 2 CD-ROM Cincinnati, OH 45240-4148 2012.


... Main factor affecting fate of fluorocarbons is body fat, where they are concentrated & slowly released into blood at concn that should not cause any risk of cardiac sensitization. /Fluorocarbons/

National Research Council. Drinking Water & Health Volume 1. Washington, DC: National Academy Press, 1977., p. 781


Abosrption of fluorocarbons is much lower after oral ingestion (35-48 times) than after inhalation. ... The lung generally has the highest fluorocarbon concentrations on autopsy. /Fluorocarbons/

Ellenhorn, M.J. and D.G. Barceloux. Medical Toxicology - Diagnosis and Treatment of Human Poisoning. New York, NY: Elsevier Science Publishing Co., Inc. 1988., p. 884


Although fluorocarbons cause cardiac sensitization in certain animal species, rapid elimination prevents the development of cardiotoxic concentrations from aerosol bronchodilator use except at exceedingly high doses (12 to 24 doses in 2 minutes). /Fluorocarbons/

Ellenhorn, M.J. and D.G. Barceloux. Medical Toxicology - Diagnosis and Treatment of Human Poisoning. New York, NY: Elsevier Science Publishing Co., Inc. 1988., p. 884


For more Absorption, Distribution and Excretion (Complete) data for 1,2-DICHLORO-1,1,2,2-TETRAFLUOROETHANE (7 total), please visit the HSDB record page.


ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty