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ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 JDMF

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Chemistry

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Also known as: 1190-53-0, Buformin hcl, Buformine hcl, N-butyl biguanide hydrochloride, Silubin, Buformin (hydrochloride)

Molecular Formula

C₆H₁₆ClN₅

Molecular Weight

193.68 g/mol

InChI Key

KKLWSPPIRBIEOV-UHFFFAOYSA-N

FDA UNII

D947SXO87P

An oral hypoglycemic agent that inhibits gluconeogenesis, increases glycolysis, and decreases glucose oxidation.

1 2D Structure

1190-53-0

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-butyl-1-(diaminomethylidene)guanidine;hydrochloride

2.1.2 InChI

InChI=1S/C6H15N5.ClH/c1-2-3-4-10-6(9)11-5(7)8;/h2-4H2,1H3,(H6,7,8,9,10,11);1H

2.1.3 InChI Key

KKLWSPPIRBIEOV-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCCCN=C(N)N=C(N)N.Cl

2.2 Other Identifiers

2.2.1 UNII

D947SXO87P

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 1 Butylbiguanide

2. 1-butylbiguanide

3. Adebit

4. Buformin

5. Butylbiguanide

6. Gliporal

7. Retard, Silubin

8. Silubin

9. Silubin Retard

2.3.2 Depositor-Supplied Synonyms

1. 1190-53-0

2. Buformin Hcl

3. Buformine Hcl

4. N-butyl Biguanide Hydrochloride

5. Silubin

6. Buformin (hydrochloride)

7. Panformin

8. Sindiatil

9. 1-butylbiguanide Hydrochloride

10. 15537-73-2

11. Biforon

12. Diabrin

13. Adebit

14. Andere

15. Butylbiguanide Hydrochloride

16. Dbv Hydrochloride

17. Butyl Guanylguanidine

18. Buformin Hydrochloride [jan]

19. N-butylimidodicarbonimidic Diamide Hydrochloride

20. 2-butyl-1-(diaminomethylidene)guanidine;hydrochloride

21. Nsc-113665

22. Nsc-528218

23. Imidodicarbonimidicdiamide, N-butyl-, Hydrochloride (1:1)

24. Sb 103

25. Imidodicarbonimidic Diamide, N-butyl-, Hydrochloride (1:)

26. D947sxo87p

27. Nsc113665

28. 1-butyl-3-carbamimidoylguanidine;hydrochloride

29. W37

30. Butyl-biguanide Hydrochloride

31. Imidodicarbonimidic Diamide, N-butyl-, Hydrochloride

32. Dibetos-b (tn)

33. Buformin Hydrochloride (jp17)

34. 1-n-butylbiguanide Hydrochloride

35. Hy-b2099a

36. Dtxsid50922844

37. Imidodicarbonimidic Diamide, N-butyl-, Hydrochloride (1:1)

38. Buformin Hydrochloride [mi]

39. 2-pyrrolidin-1-ylmethyl-acrylicacid

40. Einecs 239-587-5

41. Mfcd00045591

42. Nsc528218

43. Akos005256824

44. Buformin Hydrochloride [who-dd]

45. As-11601

46. Db-041440

47. B6007

48. Cs-0106137

49. Ft-0633441

50. 1-butyl-3-carbamimidoyl-guanidine Hydrochloride

51. D02206

52. 190b530

53. A910589

54. Buformin Hydrochloride 100 Microg/ml In Methanol

55. J-004063

56. Buformin Hydrochloride 100 Microg/ml In Acetonitrile

57. N-[amino(butylamino)methylidene]guanidine Hydrochloride

58. Q27276263

59. Z1691545036

60. N-butyltriimidodicarbonic Diamide--hydrogen Chloride (1/1)

61. N'-butyl-1-[(diaminomethylidene)amino]methanimidamide Hydrochloride

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₆H₁₆ClN₅
Molecular Weight	193.68 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	4
Exact Mass	193.1094232 g/mol
Monoisotopic Mass	193.1094232 g/mol
Topological Polar Surface Area	103 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	156
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2