Find 2-Hydroxyflutamide manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 52806-53-8, 2-hydroxyflutamide, Hydroxyniphtholide, 2-hydroxy-2-methyl-n-(4-nitro-3-(trifluoromethyl)phenyl)propanamide, Hydroxy-flutamide, 2-hydroxy-2-methyl-n-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
Molecular Formula
C11H11F3N2O4
Molecular Weight
292.21  g/mol
InChI Key
YPQLFJODEKMJEF-UHFFFAOYSA-N
FDA UNII
31D90UKP5Y

2-Hydroxyflutamide
1 2D Structure

2-Hydroxyflutamide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide
2.1.2 InChI
InChI=1S/C11H11F3N2O4/c1-10(2,18)9(17)15-6-3-4-8(16(19)20)7(5-6)11(12,13)14/h3-5,18H,1-2H3,(H,15,17)
2.1.3 InChI Key
YPQLFJODEKMJEF-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)(C(=O)NC1=CC(=C(C=C1)[N+](=O)[O-])C(F)(F)F)O
2.2 Other Identifiers
2.2.1 UNII
31D90UKP5Y
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-hydroxyflutamide

2. Oh-flutamide

3. Sch 16423

4. Sch-16423

2.3.2 Depositor-Supplied Synonyms

1. 52806-53-8

2. 2-hydroxyflutamide

3. Hydroxyniphtholide

4. 2-hydroxy-2-methyl-n-(4-nitro-3-(trifluoromethyl)phenyl)propanamide

5. Hydroxy-flutamide

6. 2-hydroxy-2-methyl-n-[4-nitro-3-(trifluoromethyl)phenyl]propanamide

7. Sch 16423

8. Hydroxy Flutamide

9. 2-hydroxy-2-methyl-n-(4-nitro-3-(trifluoromethyl)-phenyl)propanamide

10. .alpha.-hydroxyflutamide

11. Chembl491

12. Propanamide, 2-hydroxy-2-methyl-n-[4-nitro-3-(trifluoromethyl)phenyl]-

13. 31d90ukp5y

14. 2-hydroxy-flutamide

15. Oh-flutamide

16. Propanamide, 2-hydroxy-2-methyl-n-(4-nitro-3-(trifluoromethyl)phenyl)-

17. Dsstox_cid_13562

18. Dsstox_rid_79084

19. Dsstox_gsid_33562

20. Hft

21. Hydroxyflutamid

22. Liproca Depot

23. 2-hydroxy-2-methyl-n-[4-nitro-3-(trifluoromethyl)phenyl]propanamide (2-hydroxyflutamide)

24. Smr001227196

25. Cas-52806-53-8

26. Unii-31d90ukp5y

27. 2-hydroxy Flutamide

28. Mfcd00563126

29. 2ax6

30. Alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-m-lactotoluidide

31. 2-hof

32. Cid_91649

33. Mls001061267

34. Mls006011954

35. Bidd:er0519

36. Gtpl2862

37. Schembl3079778

38. Dtxsid8033562

39. Schembl19117358

40. Bdbm35909

41. Hms3039a05

42. Bcp12495

43. Hydroxyflutamide, >=98% (hplc)

44. Zinc4655055

45. Tox21_201204

46. Tox21_303659

47. Hydroxyflutamide (hydroxyniphtholide)

48. Akos007930906

49. Cs-w013988

50. Hy-w013272

51. Sb17029

52. S10360

53. Ncgc00091014-01

54. Ncgc00091014-02

55. Ncgc00091014-03

56. Ncgc00091014-04

57. Ncgc00091014-06

58. Ncgc00257382-01

59. Ncgc00258756-01

60. Bs-17460

61. A1728

62. Ft-0627147

63. H1600

64. A21118

65. Q15633976

66. 2-hydroxy-4'-nitro-3'-(trifluoromethyl)isobutyranilide

67. Z1617901126

68. 2-hydroxy-2-methyl-n-[4-nitro-3-(trifluoromethyl)phenyl]propionamide

69. 2-hydroxy-2-methyl-n-(4-nitro-3-trifluoromethyl-phenyl)-propionamide (hydroxy Flutamide)

70. 2-hydroxy-2-methyl-n-(4-nitro-3-trifluoromethyl-phenyl)-propionamide(hydroxyflutamide)

71. 2-hydroxy-2-methyl-n-(4-nitro-3-(trifluoromethyl)phenyl)propanamide; Hydroxyniphtholide

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 292.21 g/mol
Molecular Formula C11H11F3N2O4
XLogP32.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass292.06709132 g/mol
Monoisotopic Mass292.06709132 g/mol
Topological Polar Surface Area95.2 Ų
Heavy Atom Count20
Formal Charge0
Complexity392
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Androgen Antagonists

Compounds which inhibit or antagonize the biosynthesis or actions of androgens. (See all compounds classified as Androgen Antagonists.)


4.2 Metabolism/Metabolites

2-hydroxy-flutamide is a known human metabolite of flutamide.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


ABOUT THIS PAGE

2-Hydroxyflutamide Manufacturers

A 2-Hydroxyflutamide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 2-Hydroxyflutamide, including repackagers and relabelers. The FDA regulates 2-Hydroxyflutamide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 2-Hydroxyflutamide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

2-Hydroxyflutamide Suppliers

A 2-Hydroxyflutamide supplier is an individual or a company that provides 2-Hydroxyflutamide active pharmaceutical ingredient (API) or 2-Hydroxyflutamide finished formulations upon request. The 2-Hydroxyflutamide suppliers may include 2-Hydroxyflutamide API manufacturers, exporters, distributors and traders.

2-Hydroxyflutamide GMP

2-Hydroxyflutamide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 2-Hydroxyflutamide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 2-Hydroxyflutamide GMP manufacturer or 2-Hydroxyflutamide GMP API supplier for your needs.

2-Hydroxyflutamide CoA

A 2-Hydroxyflutamide CoA (Certificate of Analysis) is a formal document that attests to 2-Hydroxyflutamide's compliance with 2-Hydroxyflutamide specifications and serves as a tool for batch-level quality control.

2-Hydroxyflutamide CoA mostly includes findings from lab analyses of a specific batch. For each 2-Hydroxyflutamide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

2-Hydroxyflutamide may be tested according to a variety of international standards, such as European Pharmacopoeia (2-Hydroxyflutamide EP), 2-Hydroxyflutamide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (2-Hydroxyflutamide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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