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Chemistry

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Also known as: 42013-20-7, N-(o-toluoyl)glycine, O-toluric acid, N-(2-methylbenzoyl)glycine, O-methylhippuric acid, 2-(2-methylbenzamido)acetic acid
Molecular Formula
C10H11NO3
Molecular Weight
193.20  g/mol
InChI Key
YOEBAVRJHRCKRE-UHFFFAOYSA-N
FDA UNII
J043BCI40Z

2-Methylhippuric Acid
2-Methylhippuric Acid is an isoform of methylhippuric acid where the methyl and glycine groups are bound to carbon-1 and carbon-2 on the benzene ring, respectively. Since 2-methylhippuric acid (2-MHA) is a metabolite of o-xylene, the measurement of 2-MHA in urine may be correlated to a subject's level of xylene exposure.
1 2D Structure

2-Methylhippuric Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[(2-methylbenzoyl)amino]acetic acid
2.1.2 InChI
InChI=1S/C10H11NO3/c1-7-4-2-3-5-8(7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13)
2.1.3 InChI Key
YOEBAVRJHRCKRE-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC=CC=C1C(=O)NCC(=O)O
2.2 Other Identifiers
2.2.1 UNII
J043BCI40Z
2.3 Synonyms
2.3.1 MeSH Synonyms

1. O-methylhippuric Acid

2. Ortho-methylhippuric Acid

2.3.2 Depositor-Supplied Synonyms

1. 42013-20-7

2. N-(o-toluoyl)glycine

3. O-toluric Acid

4. N-(2-methylbenzoyl)glycine

5. O-methylhippuric Acid

6. 2-(2-methylbenzamido)acetic Acid

7. 2-methyl Hippuric Acid

8. Glycine, N-(2-methylbenzoyl)-

9. 2-[(2-methylbenzoyl)amino]acetic Acid

10. 2-[(2-methylphenyl)formamido]acetic Acid

11. N-(o-toluoyl)-glycine

12. Ortho-methylhippuric Acid

13. Mls001002411

14. J043bci40z

15. Chebi:68455

16. Nsc-163983

17. Smr000368956

18. Nsc 163983

19. Unii-j043bci40z

20. Einecs 255-622-7

21. Opera_id_915

22. N-(methylbenzoyl)glycine

23. N-(methylbenzoyl)-glycine

24. Toluric Acid, O-

25. 2-methylhippuricacid

26. Oprea1_321487

27. N-(2-methylbenzoyl)-glycine

28. 2-methylhippuric Acid, 98%

29. Chembl457228

30. Schembl1285567

31. 2-(2-methylbenzamido)aceticacid

32. Dtxsid60194818

33. Hms1755d21

34. Hms2688m04

35. Zinc389513

36. Mfcd00050991

37. N-[(2-methylphenyl)carbonyl]glycine

38. Nsc163983

39. Stl483031

40. Akos000264575

41. [(2-methylbenzoyl)amino]acetic Acid #

42. Cs-w015776

43. Hy-w015060

44. Ncgc00246096-01

45. As-10313

46. Db-025911

47. Ft-0613051

48. T0719

49. D84129

50. M-3778

51. A825717

52. Q22132784

53. Z56983120

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 193.20 g/mol
Molecular Formula C10H11NO3
XLogP30.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass193.07389321 g/mol
Monoisotopic Mass193.07389321 g/mol
Topological Polar Surface Area66.4 Ų
Heavy Atom Count14
Formal Charge0
Complexity227
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

2-Methylhippuric Acid Manufacturers

A 2-Methylhippuric Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 2-Methylhippuric Acid, including repackagers and relabelers. The FDA regulates 2-Methylhippuric Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 2-Methylhippuric Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

2-Methylhippuric Acid Suppliers

A 2-Methylhippuric Acid supplier is an individual or a company that provides 2-Methylhippuric Acid active pharmaceutical ingredient (API) or 2-Methylhippuric Acid finished formulations upon request. The 2-Methylhippuric Acid suppliers may include 2-Methylhippuric Acid API manufacturers, exporters, distributors and traders.

2-Methylhippuric Acid GMP

2-Methylhippuric Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 2-Methylhippuric Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 2-Methylhippuric Acid GMP manufacturer or 2-Methylhippuric Acid GMP API supplier for your needs.

2-Methylhippuric Acid CoA

A 2-Methylhippuric Acid CoA (Certificate of Analysis) is a formal document that attests to 2-Methylhippuric Acid's compliance with 2-Methylhippuric Acid specifications and serves as a tool for batch-level quality control.

2-Methylhippuric Acid CoA mostly includes findings from lab analyses of a specific batch. For each 2-Methylhippuric Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

2-Methylhippuric Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (2-Methylhippuric Acid EP), 2-Methylhippuric Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (2-Methylhippuric Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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