Find 2-Naphthalenepropanoic Acid manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Dx-9065a, 155204-81-2, Qxqvepevi2, Dx-9065a hcl hydrate, 155204-81-2 (hcl, hydrate), X-9065a
Molecular Formula
C26H39ClN4O8
Molecular Weight
571.1  g/mol
InChI Key
LJCBAPRMNYSDOP-LVCYMWGESA-N
FDA UNII
QXQVEPEVI2

2-Naphthalenepropanoic Acid
1 2D Structure

2-Naphthalenepropanoic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-[(3S)-1-ethanimidoylpyrrolidin-3-yl]oxyphenyl]propanoic acid;pentahydrate;hydrochloride
2.1.2 InChI
InChI=1S/C26H28N4O3.ClH.5H2O/c1-16(27)30-11-10-23(15-30)33-22-8-6-19(7-9-22)24(26(31)32)13-17-2-3-18-4-5-20(25(28)29)14-21(18)12-17;;;;;;/h2-9,12,14,23-24,27H,10-11,13,15H2,1H3,(H3,28,29)(H,31,32);1H;5*1H2/t23-,24-;;;;;;/m0....../s1
2.1.3 InChI Key
LJCBAPRMNYSDOP-LVCYMWGESA-N
2.1.4 Canonical SMILES
CC(=N)N1CCC(C1)OC2=CC=C(C=C2)C(CC3=CC4=C(C=C3)C=CC(=C4)C(=N)N)C(=O)O.O.O.O.O.O.Cl
2.1.5 Isomeric SMILES
CC(=N)N1CC[C@@H](C1)OC2=CC=C(C=C2)[C@H](CC3=CC4=C(C=C3)C=CC(=C4)C(=N)N)C(=O)O.O.O.O.O.O.Cl
2.2 Other Identifiers
2.2.1 UNII
QXQVEPEVI2
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (2s)-2-(4-(((3s)-1-acetimidoyl-3-pyrrolidinyl)oxy)phenyl)-3-(7-amidino-2-naphtyl)propanoic Acid

2. Dx 9065

3. Dx 9065a

4. Dx-9065a

2.3.2 Depositor-Supplied Synonyms

1. Dx-9065a

2. 155204-81-2

3. Qxqvepevi2

4. Dx-9065a Hcl Hydrate

5. 155204-81-2 (hcl, Hydrate)

6. X-9065a

7. Dx 9065a

8. (s)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-(((s)-1-(1-iminoethyl)pyrrolidin-3-yl)oxy)phenyl)propanoic Acid Hydrochloride Pentahydrate

9. Dx-9065 Hydrochloride Pentahydrate

10. Unii-qxqvepevi2

11. (s-(r*,r*))-7-(aminoiminomethyl)-alpha-(4-((1-(1-iminoethyl)-3-pyrrolidinyl)oxy)phenyl)-2-naphthalenepropanoic Acid Monohydrochloride, Pentahydrate

12. Dtxsid60935162

13. (2s)-2-(4-(((3s)-1-acetimidoyl-3-pyrrolidinyl)oxy)phenyl)-3-(7-amidino-2-naphtyl)propanoic Acid

14. 2-naphthalenepropanoic Acid, 7-(aminoiminomethyl)-alpha-(4-((1-(1-iminoethyl)-3-pyrrolidinyl)oxy)phenyl)-, Monohydrochloride, Pentahydrate, (s-(r*,r*))-

15. (+)-(2s)-2-[4-[[(3s)-1-acetimidoyl-3-pyrrolidi-nyl]oxy]phenyl]-3-[7-amidino-2-naphthyl] Propanoic Acid Hydrochloride Pentahydrate

16. (.alpha.s)-7-(aminoiminomethyl)-.alpha.-(4-(((3s)-1-(1-iminoethyl)-3-pyrrolidinyl)oxy)phenyl)-2-naphthalenepropanoic Acid Hydrochloride Hydrate (1:1:5)

17. (2s)-3-(7-carbamimidoylnaphthalen-2-yl)-2-[4-[(3s)-1-ethanimidoylpyrrolidin-3-yl]oxyphenyl]propanoic Acid;pentahydrate;hydrochloride

18. 2-naphthalenepropanoic Acid, 7-(aminoiminomethyl)-.alpha.-(4-(((3s)-1-(1-iminoethyl)-3-pyrrolidinyl)oxy)phenyl)-, Hydrochloride, Hydrate (1:1:5), (.alpha.s)-

19. 2-naphthalenepropanoic Acid, 7-(aminoiminomethyl)-.alpha.-(4-(((3s)-1-(1-iminoethyl)-3-pyrrolidinyl)oxy)phenyl)-, Monohydrochloride, Pentahydrate, (.alpha.s)-

20. 2-naphthalenepropanoic Acid, 7-(aminoiminomethyl)-.alpha.-(4-((1-(1-iminoethyl)-3-pyrrolidinyl)oxy)phenyl)-, Monohydrochloride, Pentahydrate, (s-(r*,r*))-

21. 2-naphthalenepropanoic Acid,7-(aminoiminomethyl)-a-[4-[[(3s)-1-(1-iminoethyl)-3-pyrrolidinyl]oxy]phenyl]-,hydrochloride,hydrate (1:1:5),(as)-

22. 3-(7-carbamimidoylnaphthalen-2-yl)-2-{4-[(1-ethanimidoylpyrrolidin-3-yl)oxy]phenyl}propanoic Acid--hydrogen Chloride--water (1/1/5)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 571.1 g/mol
Molecular Formula C26H39ClN4O8
Hydrogen Bond Donor Count10
Hydrogen Bond Acceptor Count10
Rotatable Bond Count8
Exact Mass570.2456419 g/mol
Monoisotopic Mass570.2456419 g/mol
Topological Polar Surface Area129 Ų
Heavy Atom Count39
Formal Charge0
Complexity720
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count7
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Platelet Aggregation Inhibitors

Drugs or agents which antagonize or impair any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system. (See all compounds classified as Platelet Aggregation Inhibitors.)


Anticoagulants

Agents that prevent BLOOD CLOTTING. (See all compounds classified as Anticoagulants.)


Serine Proteinase Inhibitors

Exogenous or endogenous compounds which inhibit SERINE ENDOPEPTIDASES. (See all compounds classified as Serine Proteinase Inhibitors.)


ABOUT THIS PAGE

2-Naphthalenepropanoic Acid Manufacturers

A 2-Naphthalenepropanoic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 2-Naphthalenepropanoic Acid, including repackagers and relabelers. The FDA regulates 2-Naphthalenepropanoic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 2-Naphthalenepropanoic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

2-Naphthalenepropanoic Acid Suppliers

A 2-Naphthalenepropanoic Acid supplier is an individual or a company that provides 2-Naphthalenepropanoic Acid active pharmaceutical ingredient (API) or 2-Naphthalenepropanoic Acid finished formulations upon request. The 2-Naphthalenepropanoic Acid suppliers may include 2-Naphthalenepropanoic Acid API manufacturers, exporters, distributors and traders.

click here to find a list of 2-Naphthalenepropanoic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

2-Naphthalenepropanoic Acid USDMF

A 2-Naphthalenepropanoic Acid DMF (Drug Master File) is a document detailing the whole manufacturing process of 2-Naphthalenepropanoic Acid active pharmaceutical ingredient (API) in detail. Different forms of 2-Naphthalenepropanoic Acid DMFs exist exist since differing nations have different regulations, such as 2-Naphthalenepropanoic Acid USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A 2-Naphthalenepropanoic Acid DMF submitted to regulatory agencies in the US is known as a USDMF. 2-Naphthalenepropanoic Acid USDMF includes data on 2-Naphthalenepropanoic Acid's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The 2-Naphthalenepropanoic Acid USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of 2-Naphthalenepropanoic Acid suppliers with USDMF on PharmaCompass.

2-Naphthalenepropanoic Acid GMP

2-Naphthalenepropanoic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 2-Naphthalenepropanoic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 2-Naphthalenepropanoic Acid GMP manufacturer or 2-Naphthalenepropanoic Acid GMP API supplier for your needs.

2-Naphthalenepropanoic Acid CoA

A 2-Naphthalenepropanoic Acid CoA (Certificate of Analysis) is a formal document that attests to 2-Naphthalenepropanoic Acid's compliance with 2-Naphthalenepropanoic Acid specifications and serves as a tool for batch-level quality control.

2-Naphthalenepropanoic Acid CoA mostly includes findings from lab analyses of a specific batch. For each 2-Naphthalenepropanoic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

2-Naphthalenepropanoic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (2-Naphthalenepropanoic Acid EP), 2-Naphthalenepropanoic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (2-Naphthalenepropanoic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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