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Chemistry

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Also known as: Phenibut, 1078-21-3, Fenibut, 4-amino-3-phenylbutyric acid, Phgaba, Phenylgamma
Molecular Formula
C10H13NO2
Molecular Weight
179.22  g/mol
InChI Key
DAFOCGYVTAOKAJ-UHFFFAOYSA-N
FDA UNII
T2M58D6LA8

4-Amino-3-Phenylbutanoic Acid
1 2D Structure

4-Amino-3-Phenylbutanoic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-amino-3-phenylbutanoic acid
2.1.2 InChI
InChI=1S/C10H13NO2/c11-7-9(6-10(12)13)8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)
2.1.3 InChI Key
DAFOCGYVTAOKAJ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC=C(C=C1)C(CC(=O)O)CN
2.2 Other Identifiers
2.2.1 UNII
T2M58D6LA8
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-amino-3-phenylbutyric Acid

2. 4-amino-3-phenylbutyric Acid Hydrochloride

3. 4-amino-3-phenylbutyric Acid, (dl)-(+-)-mixture

4. 4-amino-3-phenylbutyric Acid, (l)-(-)-isomer

5. Beta-(aminomethyl)benzenepropanoic Acid

6. Beta-(aminomethyl)hydrocinnamic Acid

7. Beta-phenyl-gamma-aminobutyric Acid

8. Citrocard

9. Fenibut

10. Fenibut Citrate

11. Noophen

12. Phenibut

13. Phenybut

14. Phenyl-gaba

2.3.2 Depositor-Supplied Synonyms

1. Phenibut

2. 1078-21-3

3. Fenibut

4. 4-amino-3-phenylbutyric Acid

5. Phgaba

6. Phenylgamma

7. Phenigamma

8. Fenigama

9. Phenigam

10. Phenylgam

11. Pgaba

12. Fenigam

13. Phenygam

14. Beta-phenyl-gamma-aminobutyric Acid

15. Beta-(aminomethyl)hydrocinnamic Acid

16. Beta-phenyl-gamma-aminobutyrate

17. 4-amino-3-phenyl-butyric Acid

18. Beta-(aminomethyl)benzenepropanoic Acid

19. Benzenepropanoic Acid, .beta.-(aminomethyl)-

20. 4-amino-3-pheny-butyric Acid

21. T2m58d6la8

22. Dl-4-amino-3-phenylbutanoic Acid

23. Phenyl-gaba

24. Phenigama

25. Einecs 214-079-6

26. Brn 2804903

27. Unii-t2m58d6la8

28. Benzenepropanoic Acid, Beta-(aminomethyl)-

29. Phenibut; Fenibut

30. Benzenepropanoic Acid, Beta-(aminomethyl)-, Hydrochloride

31. Butyric Acid, 4-amino-3-phenyl-

32. Phenibut [who-dd]

33. Oprea1_183000

34. Oprea1_381119

35. 4-14-00-01723 (beilstein Handbook Reference)

36. (+/-)-fenibut

37. Schembl340838

38. 3-phenyl-4-aminobutanoic Acid

39. Chembl315818

40. Dtxsid70870838

41. Ex-a734

42. Chebi:136039

43. Hms3886k05

44. (s)-4-amino-3-phenylbutanoicacid

45. Albb-022462

46. Bcp10710

47. Bbl000576

48. Mfcd00456233

49. S4892

50. Stk182861

51. (+/-)-.beta.-phenyl-gaba

52. 3-amino-2-phenylpropanecarboxylic Acid

53. Akos000555914

54. Akos016347357

55. Ccg-266416

56. Db13455

57. Gs-3145

58. Benzenepropanoic Acid, B-(aminomethyl)-

59. 4-amino-3-phenylbutyric Acid [mi]

60. Ft-0600356

61. .beta.-(aminomethyl)hydrocinnamic Acid

62. D10509

63. D96082

64. .beta.-(aminomethyl)benzenepropanoic Acid

65. .beta.-phenyl-.gamma.-aminobutyric Acid

66. 078a213

67. Q419559

68. Z1436181457

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 179.22 g/mol
Molecular Formula C10H13NO2
XLogP3-1.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass179.094628657 g/mol
Monoisotopic Mass179.094628657 g/mol
Topological Polar Surface Area63.3 Ų
Heavy Atom Count13
Formal Charge0
Complexity164
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anticonvulsants

Drugs used to prevent SEIZURES or reduce their severity. (See all compounds classified as Anticonvulsants.)


Hypnotics and Sedatives

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)


Convulsants

Substances that act in the brain stem or spinal cord to produce tonic or clonic convulsions, often by removing normal inhibitory tone. They were formerly used to stimulate respiration or as antidotes to barbiturate overdose. They are now most commonly used as experimental tools. (See all compounds classified as Convulsants.)


GABA Agonists

Endogenous compounds and drugs that bind to and activate GAMMA-AMINOBUTYRIC ACID receptors (RECEPTORS, GABA). (See all compounds classified as GABA Agonists.)


Tranquilizing Agents

A traditional grouping of drugs said to have a soothing or calming effect on mood, thought, or behavior. Included here are the ANTI-ANXIETY AGENTS (minor tranquilizers), ANTIMANIC AGENTS, and the ANTIPSYCHOTIC AGENTS (major tranquilizers). These drugs act by different mechanisms and are used for different therapeutic purposes. (See all compounds classified as Tranquilizing Agents.)


4.2 ATC Code

N - Nervous system

N06 - Psychoanaleptics

N06B - Psychostimulants, agents used for adhd and nootropics

N06BX - Other psychostimulants and nootropics

N06BX22 - Phenibut


API Reference Price

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12-Jun-2021
29-Oct-2022
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4-Amino-3-Phenylbutanoic Acid Manufacturers

A 4-Amino-3-Phenylbutanoic Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 4-Amino-3-Phenylbutanoic Acid, including repackagers and relabelers. The FDA regulates 4-Amino-3-Phenylbutanoic Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 4-Amino-3-Phenylbutanoic Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of 4-Amino-3-Phenylbutanoic Acid manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

4-Amino-3-Phenylbutanoic Acid Suppliers

A 4-Amino-3-Phenylbutanoic Acid supplier is an individual or a company that provides 4-Amino-3-Phenylbutanoic Acid active pharmaceutical ingredient (API) or 4-Amino-3-Phenylbutanoic Acid finished formulations upon request. The 4-Amino-3-Phenylbutanoic Acid suppliers may include 4-Amino-3-Phenylbutanoic Acid API manufacturers, exporters, distributors and traders.

click here to find a list of 4-Amino-3-Phenylbutanoic Acid suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

4-Amino-3-Phenylbutanoic Acid GMP

4-Amino-3-Phenylbutanoic Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 4-Amino-3-Phenylbutanoic Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 4-Amino-3-Phenylbutanoic Acid GMP manufacturer or 4-Amino-3-Phenylbutanoic Acid GMP API supplier for your needs.

4-Amino-3-Phenylbutanoic Acid CoA

A 4-Amino-3-Phenylbutanoic Acid CoA (Certificate of Analysis) is a formal document that attests to 4-Amino-3-Phenylbutanoic Acid's compliance with 4-Amino-3-Phenylbutanoic Acid specifications and serves as a tool for batch-level quality control.

4-Amino-3-Phenylbutanoic Acid CoA mostly includes findings from lab analyses of a specific batch. For each 4-Amino-3-Phenylbutanoic Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

4-Amino-3-Phenylbutanoic Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (4-Amino-3-Phenylbutanoic Acid EP), 4-Amino-3-Phenylbutanoic Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (4-Amino-3-Phenylbutanoic Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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