Find 4-Des-Dimethylaminotetracycline manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Cmt-1, 4-dedimethylaminotetracycline, 2444-65-7, Chembl3622800, 4-des-dimethylaminotetracycline, 4-de-dimethylaminotetracycline
Molecular Formula
C20H19NO8
Molecular Weight
401.4  g/mol
InChI Key
XCCHQGIGHCRZOS-KBKZQPOHSA-N

4-Des-Dimethylaminotetracycline
1 2D Structure

4-Des-Dimethylaminotetracycline

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4aS,5aS,6S,12aR)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide
2.1.2 InChI
InChI=1S/C20H19NO8/c1-19(28)8-3-2-4-10(22)12(8)15(24)13-9(19)5-7-6-11(23)14(18(21)27)17(26)20(7,29)16(13)25/h2-4,7,9,22,24,26,28-29H,5-6H2,1H3,(H2,21,27)/t7-,9-,19+,20-/m0/s1
2.1.3 InChI Key
XCCHQGIGHCRZOS-KBKZQPOHSA-N
2.1.4 Canonical SMILES
CC1(C2CC3CC(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)O
2.1.5 Isomeric SMILES
C[C@@]1([C@H]2C[C@H]3CC(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 4-de-dimethylaminotetracycline

2. 4-dedimethylaminotetracycline

3. 4-des-dimethylaminotetracycline

4. Cmt-1

2.2.2 Depositor-Supplied Synonyms

1. Cmt-1

2. 4-dedimethylaminotetracycline

3. 2444-65-7

4. Chembl3622800

5. 4-des-dimethylaminotetracycline

6. 4-de-dimethylaminotetracycline

7. 4-de(dimethylamino)tetracycline

8. Schembl2614027

9. Bdbm170149

10. Zinc4879584

11. Bdbm50124122

12. (4as,5as,6s,12ar)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide

13. 2-naphthacenecarboxamide, 1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4as-(4aalpha,5aalpha,6beta,12aalpha))-

2.3 Create Date
2011-12-26
3 Chemical and Physical Properties
Molecular Weight 401.4 g/mol
Molecular Formula C20H19NO8
XLogP30.1
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count8
Rotatable Bond Count1
Exact Mass401.11106656 g/mol
Monoisotopic Mass401.11106656 g/mol
Topological Polar Surface Area178 Ų
Heavy Atom Count29
Formal Charge0
Complexity891
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Matrix Metalloproteinase Inhibitors

Compounds that inhibit the enzyme activity or activation of MATRIX METALLOPROTEINASES. (See all compounds classified as Matrix Metalloproteinase Inhibitors.)


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ABOUT THIS PAGE

4-Des-Dimethylaminotetracycline Manufacturers

A 4-Des-Dimethylaminotetracycline manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 4-Des-Dimethylaminotetracycline, including repackagers and relabelers. The FDA regulates 4-Des-Dimethylaminotetracycline manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 4-Des-Dimethylaminotetracycline API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

4-Des-Dimethylaminotetracycline Suppliers

A 4-Des-Dimethylaminotetracycline supplier is an individual or a company that provides 4-Des-Dimethylaminotetracycline active pharmaceutical ingredient (API) or 4-Des-Dimethylaminotetracycline finished formulations upon request. The 4-Des-Dimethylaminotetracycline suppliers may include 4-Des-Dimethylaminotetracycline API manufacturers, exporters, distributors and traders.

click here to find a list of 4-Des-Dimethylaminotetracycline suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

4-Des-Dimethylaminotetracycline USDMF

A 4-Des-Dimethylaminotetracycline DMF (Drug Master File) is a document detailing the whole manufacturing process of 4-Des-Dimethylaminotetracycline active pharmaceutical ingredient (API) in detail. Different forms of 4-Des-Dimethylaminotetracycline DMFs exist exist since differing nations have different regulations, such as 4-Des-Dimethylaminotetracycline USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A 4-Des-Dimethylaminotetracycline DMF submitted to regulatory agencies in the US is known as a USDMF. 4-Des-Dimethylaminotetracycline USDMF includes data on 4-Des-Dimethylaminotetracycline's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The 4-Des-Dimethylaminotetracycline USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of 4-Des-Dimethylaminotetracycline suppliers with USDMF on PharmaCompass.

4-Des-Dimethylaminotetracycline GMP

4-Des-Dimethylaminotetracycline Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 4-Des-Dimethylaminotetracycline GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 4-Des-Dimethylaminotetracycline GMP manufacturer or 4-Des-Dimethylaminotetracycline GMP API supplier for your needs.

4-Des-Dimethylaminotetracycline CoA

A 4-Des-Dimethylaminotetracycline CoA (Certificate of Analysis) is a formal document that attests to 4-Des-Dimethylaminotetracycline's compliance with 4-Des-Dimethylaminotetracycline specifications and serves as a tool for batch-level quality control.

4-Des-Dimethylaminotetracycline CoA mostly includes findings from lab analyses of a specific batch. For each 4-Des-Dimethylaminotetracycline CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

4-Des-Dimethylaminotetracycline may be tested according to a variety of international standards, such as European Pharmacopoeia (4-Des-Dimethylaminotetracycline EP), 4-Des-Dimethylaminotetracycline JP (Japanese Pharmacopeia) and the US Pharmacopoeia (4-Des-Dimethylaminotetracycline USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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