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Chemistry

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Also known as: (2s)-4-hydroxypyrrolidine-2-carboxylic acid, 4-hydroxyproline, 6912-67-0, Cis-hydroxyproline, The (r)-4-hydroxy l-isomer has been assumedunless otherwise specified or implied in the original document and is indexed at l-proline,4-hydroxy-,(4r)- [51-35-4]. when synthetichydroxyproline has been clearly indicated in theoriginal document,the 4-hydroxy, Proline, 4-hydroxy-
Molecular Formula
C5H9NO3
Molecular Weight
131.13  g/mol
InChI Key
PMMYEEVYMWASQN-BKLSDQPFSA-N

4-Hydroxy-L-Proline
A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
1 2D Structure

4-Hydroxy-L-Proline

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-4-hydroxypyrrolidine-2-carboxylic acid
2.1.2 InChI
InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3?,4-/m0/s1
2.1.3 InChI Key
PMMYEEVYMWASQN-BKLSDQPFSA-N
2.1.4 Canonical SMILES
C1C(CNC1C(=O)O)O
2.1.5 Isomeric SMILES
C1[C@H](NCC1O)C(=O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 4 Hydroxyproline

2. 4-hydroxyproline

3. Cis 4 Hydroxyproline

4. Cis-4-hydroxyproline

5. Hydroxyproline

6. Oxyproline

2.2.2 Depositor-Supplied Synonyms

1. (2s)-4-hydroxypyrrolidine-2-carboxylic Acid

2. 4-hydroxyproline

3. 6912-67-0

4. Cis-hydroxyproline

5. The (r)-4-hydroxy L-isomer Has Been Assumedunless Otherwise Specified Or Implied In The Original Document And Is Indexed At L-proline,4-hydroxy-,(4r)- [51-35-4]. When Synthetichydroxyproline Has Been Clearly Indicated In Theoriginal Document,the 4-hydroxy

6. Proline, 4-hydroxy-

7. L-allohydroxyproline

8. Allo-l-hydroxyproline

9. Allo-4-hydroxyproline

10. Allo-hydroxy-l-proline

11. L-proline, Allo-hydroxy-

12. L-proline, 4-hydroxy-, Cis-

13. Proline, 4-allo-hydroxy-, L-

14. Nsc 206274

15. 4-hydroxy-proline

16. 4hydroxy-l-proline

17. 30724-02-8

18. Cis-4-hydroxy-l-pro

19. 4-hydroxy-(l)-proline

20. 4-cis-hydroxy-l-proline

21. Schembl21184

22. 4-hydroxy-l-proline, (z)-

23. L-proline, Allo-hydroxy-, Cis

24. Chebi:18240

25. Cis-proline, 4-allo-hydroxy-, L-

26. As-10781

27. Cs-0526696

28. H0296

29. A820581

30. Q27102938

2.3 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 131.13 g/mol
Molecular Formula C5H9NO3
XLogP3-3.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass131.058243149 g/mol
Monoisotopic Mass131.058243149 g/mol
Topological Polar Surface Area69.6 Ų
Heavy Atom Count9
Formal Charge0
Complexity125
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API Reference Price

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27-Jan-2021
12-Dec-2024
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Quantity (KGS) & Unit rate (USD/KGS) over time

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ABOUT THIS PAGE

4-Hydroxy-L-Proline Manufacturers

A 4-Hydroxy-L-Proline manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 4-Hydroxy-L-Proline, including repackagers and relabelers. The FDA regulates 4-Hydroxy-L-Proline manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 4-Hydroxy-L-Proline API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of 4-Hydroxy-L-Proline manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

4-Hydroxy-L-Proline Suppliers

A 4-Hydroxy-L-Proline supplier is an individual or a company that provides 4-Hydroxy-L-Proline active pharmaceutical ingredient (API) or 4-Hydroxy-L-Proline finished formulations upon request. The 4-Hydroxy-L-Proline suppliers may include 4-Hydroxy-L-Proline API manufacturers, exporters, distributors and traders.

click here to find a list of 4-Hydroxy-L-Proline suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

4-Hydroxy-L-Proline GMP

4-Hydroxy-L-Proline Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 4-Hydroxy-L-Proline GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 4-Hydroxy-L-Proline GMP manufacturer or 4-Hydroxy-L-Proline GMP API supplier for your needs.

4-Hydroxy-L-Proline CoA

A 4-Hydroxy-L-Proline CoA (Certificate of Analysis) is a formal document that attests to 4-Hydroxy-L-Proline's compliance with 4-Hydroxy-L-Proline specifications and serves as a tool for batch-level quality control.

4-Hydroxy-L-Proline CoA mostly includes findings from lab analyses of a specific batch. For each 4-Hydroxy-L-Proline CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

4-Hydroxy-L-Proline may be tested according to a variety of international standards, such as European Pharmacopoeia (4-Hydroxy-L-Proline EP), 4-Hydroxy-L-Proline JP (Japanese Pharmacopeia) and the US Pharmacopoeia (4-Hydroxy-L-Proline USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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