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Chemistry

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Also known as: (2s)-4-hydroxypyrrolidine-2-carboxylic acid, 4-hydroxyproline, 6912-67-0, Cis-hydroxyproline, The (r)-4-hydroxy l-isomer has been assumedunless otherwise specified or implied in the original document and is indexed at l-proline,4-hydroxy-,(4r)- [51-35-4]. when synthetichydroxyproline has been clearly indicated in theoriginal document,the 4-hydroxy, Proline, 4-hydroxy-
Molecular Formula
C5H9NO3
Molecular Weight
131.13  g/mol
InChI Key
PMMYEEVYMWASQN-BKLSDQPFSA-N

4-Hydroxy-L-Proline
A hydroxylated form of the imino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation.
1 2D Structure

4-Hydroxy-L-Proline

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-4-hydroxypyrrolidine-2-carboxylic acid
2.1.2 InChI
InChI=1S/C5H9NO3/c7-3-1-4(5(8)9)6-2-3/h3-4,6-7H,1-2H2,(H,8,9)/t3?,4-/m0/s1
2.1.3 InChI Key
PMMYEEVYMWASQN-BKLSDQPFSA-N
2.1.4 Canonical SMILES
C1C(CNC1C(=O)O)O
2.1.5 Isomeric SMILES
C1[C@H](NCC1O)C(=O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 4 Hydroxyproline

2. 4-hydroxyproline

3. Cis 4 Hydroxyproline

4. Cis-4-hydroxyproline

5. Hydroxyproline

6. Oxyproline

2.2.2 Depositor-Supplied Synonyms

1. (2s)-4-hydroxypyrrolidine-2-carboxylic Acid

2. 4-hydroxyproline

3. 6912-67-0

4. Cis-hydroxyproline

5. The (r)-4-hydroxy L-isomer Has Been Assumedunless Otherwise Specified Or Implied In The Original Document And Is Indexed At L-proline,4-hydroxy-,(4r)- [51-35-4]. When Synthetichydroxyproline Has Been Clearly Indicated In Theoriginal Document,the 4-hydroxy

6. Proline, 4-hydroxy-

7. L-allohydroxyproline

8. Allo-l-hydroxyproline

9. Allo-4-hydroxyproline

10. Allo-hydroxy-l-proline

11. L-proline, Allo-hydroxy-

12. L-proline, 4-hydroxy-, Cis-

13. Proline, 4-allo-hydroxy-, L-

14. Nsc 206274

15. 4-hydroxy-proline

16. 4hydroxy-l-proline

17. 30724-02-8

18. Cis-4-hydroxy-l-pro

19. 4-hydroxy-(l)-proline

20. 4-cis-hydroxy-l-proline

21. Schembl21184

22. 4-hydroxy-l-proline, (z)-

23. L-proline, Allo-hydroxy-, Cis

24. Chebi:18240

25. Cis-proline, 4-allo-hydroxy-, L-

26. As-10781

27. Cs-0526696

28. H0296

29. A820581

30. Q27102938

2.3 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 131.13 g/mol
Molecular Formula C5H9NO3
XLogP3-3.3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass131.058243149 g/mol
Monoisotopic Mass131.058243149 g/mol
Topological Polar Surface Area69.6 Ų
Heavy Atom Count9
Formal Charge0
Complexity125
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

API SUPPLIERS

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01

Sichuan Tongsheng Amino Acid Co., ...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
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Sichuan Tongsheng Amino Acid Co., ...

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
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12-Mar-2021
25-Jun-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
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