Find 7-Hydroxystaurosporine manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Ucn-02, Chembl574737, 121569-61-7, Ucn 02, Kw-2401, Ucn01
Molecular Formula
C28H26N4O4
Molecular Weight
482.5  g/mol
InChI Key
PBCZSGKMGDDXIJ-KRUBCLEUSA-N

7-Hydroxystaurosporine
(2S,3R,4R,6R,18S)-18-hydroxy-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1,.0,.0,.0,.0,.0,]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one is a natural product found in Streptomyces with data available.
1 2D Structure

7-Hydroxystaurosporine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3R,4R,6R,18S)-18-hydroxy-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one
2.1.2 InChI
InChI=1S/C28H26N4O4/c1-28-25(35-3)15(29-2)12-18(36-28)31-16-10-6-4-8-13(16)19-21-22(27(34)30-26(21)33)20-14-9-5-7-11-17(14)32(28)24(20)23(19)31/h4-11,15,18,25,27,29,34H,12H2,1-3H3,(H,30,33)/t15-,18-,25-,27+,28+/m1/s1
2.1.3 InChI Key
PBCZSGKMGDDXIJ-KRUBCLEUSA-N
2.1.4 Canonical SMILES
CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)C(NC6=O)O)NC)OC
2.1.5 Isomeric SMILES
C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)[C@@H](NC6=O)O)NC)OC
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 7-epi-hydroxystaurosporine

2. 7-hydroxy-staurosporine

3. 7-hydroxystaurosporine

4. 8,12-epoxy-1h,8h-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)triinden-1-one, 2,3,9,10,11,12-hexahydro-3-hydroxy-9-methoxy-8-methyl-10-(methylamino)-

5. Ucn 01

6. Ucn 02

7. Ucn-02

2.2.2 Depositor-Supplied Synonyms

1. Ucn-02

2. Chembl574737

3. 121569-61-7

4. Ucn 02

5. Kw-2401

6. Ucn01

7. Schembl16946789

8. Dtxsid60923867

9. Hms3229l19

10. Bdbm50280450

11. Nsc800958

12. Zinc33901069

13. Nsc-800958

14. Ncgc00346827-02

15. Ucn-01, >=97% (hplc), Powder

16. 8,12-epoxy-1h,8h-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-3-hydroxy-9-methoxy-8-methyl-10-(methylamino)-

17. 9,13-epoxy-1h,9h-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)benzodiazon-1-one, 2,3,10,11,12,13-hexahydro-3-hydroxy-10-methoxy-9-methyl-11-(methylamino)-, (3-alpha,9-alpha,10-beta,11-beta,13-alpha)-

18. Hy-108262

19. Cs-0027882

20. (2s,3r,4r,6r,18s)-18-hydroxy-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one

21. 18-hydroxy-3-methoxy-2-methyl-4-methylamino-(2r,3s,4s,6s)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one

22. 8-methoxy-9-methyl-7-(methylamino)-6,7,8,9-tetrahydro-5h,14h-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacene-14,16-diol

2.3 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 482.5 g/mol
Molecular Formula C28H26N4O4
XLogP32.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass482.19540532 g/mol
Monoisotopic Mass482.19540532 g/mol
Topological Polar Surface Area89.7 Ų
Heavy Atom Count36
Formal Charge0
Complexity935
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antineoplastic Agents

Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)


Protein Kinase Inhibitors

Agents that inhibit PROTEIN KINASES. (See all compounds classified as Protein Kinase Inhibitors.)


ABOUT THIS PAGE

7-Hydroxystaurosporine Manufacturers

A 7-Hydroxystaurosporine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 7-Hydroxystaurosporine, including repackagers and relabelers. The FDA regulates 7-Hydroxystaurosporine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 7-Hydroxystaurosporine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

7-Hydroxystaurosporine Suppliers

A 7-Hydroxystaurosporine supplier is an individual or a company that provides 7-Hydroxystaurosporine active pharmaceutical ingredient (API) or 7-Hydroxystaurosporine finished formulations upon request. The 7-Hydroxystaurosporine suppliers may include 7-Hydroxystaurosporine API manufacturers, exporters, distributors and traders.

click here to find a list of 7-Hydroxystaurosporine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

7-Hydroxystaurosporine USDMF

A 7-Hydroxystaurosporine DMF (Drug Master File) is a document detailing the whole manufacturing process of 7-Hydroxystaurosporine active pharmaceutical ingredient (API) in detail. Different forms of 7-Hydroxystaurosporine DMFs exist exist since differing nations have different regulations, such as 7-Hydroxystaurosporine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A 7-Hydroxystaurosporine DMF submitted to regulatory agencies in the US is known as a USDMF. 7-Hydroxystaurosporine USDMF includes data on 7-Hydroxystaurosporine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The 7-Hydroxystaurosporine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of 7-Hydroxystaurosporine suppliers with USDMF on PharmaCompass.

7-Hydroxystaurosporine GMP

7-Hydroxystaurosporine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 7-Hydroxystaurosporine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 7-Hydroxystaurosporine GMP manufacturer or 7-Hydroxystaurosporine GMP API supplier for your needs.

7-Hydroxystaurosporine CoA

A 7-Hydroxystaurosporine CoA (Certificate of Analysis) is a formal document that attests to 7-Hydroxystaurosporine's compliance with 7-Hydroxystaurosporine specifications and serves as a tool for batch-level quality control.

7-Hydroxystaurosporine CoA mostly includes findings from lab analyses of a specific batch. For each 7-Hydroxystaurosporine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

7-Hydroxystaurosporine may be tested according to a variety of international standards, such as European Pharmacopoeia (7-Hydroxystaurosporine EP), 7-Hydroxystaurosporine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (7-Hydroxystaurosporine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty