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Chemistry

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Also known as: Silymarin, Zinc4016719, N1711
Molecular Formula
C25H22O10
Molecular Weight
482.4  g/mol
InChI Key
SEBFKMXJBCUCAI-VDVKDMFPSA-N

AC1OFCT7
A mixture of flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum. It consists primarily of silybin and its isomers, silicristin and silidianin. Silymarin displays antioxidant and membrane stabilizing activity. It protects various tissues and organs against chemical injury, and shows potential as an antihepatoxic agent.
1 2D Structure

AC1OFCT7

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3R)-3,5,7-trihydroxy-2-[(2S,3S)-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-2,3-dihydrochromen-4-one
2.1.2 InChI
InChI=1S/C25H22O10/c1-32-17-6-11(2-4-14(17)28)24-20(10-26)33-16-5-3-12(7-18(16)34-24)25-23(31)22(30)21-15(29)8-13(27)9-19(21)35-25/h2-9,20,23-29,31H,10H2,1H3/t20-,23-,24-,25-/m0/s1
2.1.3 InChI Key
SEBFKMXJBCUCAI-VDVKDMFPSA-N
2.1.4 Canonical SMILES
COC1=C(C=CC(=C1)C2C(OC3=C(O2)C=C(C=C3)C4C(C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
2.1.5 Isomeric SMILES
COC1=C(C=CC(=C1)[C@H]2[C@@H](OC3=C(O2)C=C(C=C3)[C@H]4[C@H](C(=O)C5=C(C=C(C=C5O4)O)O)O)CO)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Carsil

2. Karsil

3. Legalon

4. Silimarin

5. Silymarin

2.2.2 Depositor-Supplied Synonyms

1. Silymarin

2. Zinc4016719

3. N1711

2.3 Create Date
2006-07-29
3 Chemical and Physical Properties
Molecular Weight 482.4 g/mol
Molecular Formula C25H22O10
XLogP32.4
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count4
Exact Mass482.12129689 g/mol
Monoisotopic Mass482.12129689 g/mol
Topological Polar Surface Area155 Ų
Heavy Atom Count35
Formal Charge0
Complexity750
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antioxidants

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)


Protective Agents

Synthetic or natural substances which are given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent. (See all compounds classified as Protective Agents.)


4.2 ATC Code

A - Alimentary tract and metabolism

A05 - Bile and liver therapy

A05B - Liver therapy, lipotropics

A05BA - Liver therapy

A05BA03 - Silymarin


ABOUT THIS PAGE

Looking for 65666-07-1 / AC1OFCT7 API manufacturers, exporters & distributors?

AC1OFCT7 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of AC1OFCT7 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right AC1OFCT7 manufacturer or AC1OFCT7 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred AC1OFCT7 manufacturer or AC1OFCT7 supplier.

PharmaCompass also assists you with knowing the AC1OFCT7 API Price utilized in the formulation of products. AC1OFCT7 API Price is not always fixed or binding as the AC1OFCT7 Price is obtained through a variety of data sources. The AC1OFCT7 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

AC1OFCT7

Synonyms

Silymarin, Zinc4016719, N1711

Cas Number

65666-07-1

About AC1OFCT7

A mixture of flavonoids extracted from seeds of the MILK THISTLE, Silybum marianum. It consists primarily of silybin and its isomers, silicristin and silidianin. Silymarin displays antioxidant and membrane stabilizing activity. It protects various tissues and organs against chemical injury, and shows potential as an antihepatoxic agent.

AC1OFCT7 Manufacturers

A AC1OFCT7 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of AC1OFCT7, including repackagers and relabelers. The FDA regulates AC1OFCT7 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. AC1OFCT7 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

AC1OFCT7 Suppliers

A AC1OFCT7 supplier is an individual or a company that provides AC1OFCT7 active pharmaceutical ingredient (API) or AC1OFCT7 finished formulations upon request. The AC1OFCT7 suppliers may include AC1OFCT7 API manufacturers, exporters, distributors and traders.

AC1OFCT7 GMP

AC1OFCT7 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of AC1OFCT7 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right AC1OFCT7 GMP manufacturer or AC1OFCT7 GMP API supplier for your needs.

AC1OFCT7 CoA

A AC1OFCT7 CoA (Certificate of Analysis) is a formal document that attests to AC1OFCT7's compliance with AC1OFCT7 specifications and serves as a tool for batch-level quality control.

AC1OFCT7 CoA mostly includes findings from lab analyses of a specific batch. For each AC1OFCT7 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

AC1OFCT7 may be tested according to a variety of international standards, such as European Pharmacopoeia (AC1OFCT7 EP), AC1OFCT7 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (AC1OFCT7 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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