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    Chemistry

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    Also known as: 77337-73-6, Campral, Campral ec, Alcomed, Sobriol, Aotal
    Molecular Formula
    C10H20CaN2O8S2
    Molecular Weight
    400.5  g/mol
    InChI Key
    BUVGWDNTAWHSKI-UHFFFAOYSA-L
    FDA UNII
    59375N1D0U
    Acamprosate Calcium
    Structural analog of taurine that is used for the prevention of relapse in individuals with ALCOHOLISM.
    1 2D Structure

    Acamprosate Calcium

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    calcium;3-acetamidopropane-1-sulfonate
    2.1.2 InChI
    InChI=1S/2C5H11NO4S.Ca/c2*1-5(7)6-3-2-4-11(8,9)10;/h2*2-4H2,1H3,(H,6,7)(H,8,9,10);/q;;+2/p-2
    2.1.3 InChI Key
    BUVGWDNTAWHSKI-UHFFFAOYSA-L
    2.1.4 Canonical SMILES
    CC(=O)NCCCS(=O)(=O)[O-].CC(=O)NCCCS(=O)(=O)[O-].[Ca+2]
    2.2 Other Identifiers
    2.2.1 UNII
    59375N1D0U
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Acamprosate

    2. Acamprostate

    3. Acetyl Homotaurinate, Calcium

    4. Acetylhomotaurinate, Calcium

    5. Acetylhomotaurine, Calcium

    6. Acetylhomotaurine, Sodium

    7. Aotal

    8. Calcium Acetyl Homotaurinate

    9. Calcium Acetylhomotaurinate

    10. Calcium Acetylhomotaurine

    11. Campral

    12. Campral Ec

    13. N Acetylhomotaurine

    14. N Acetylhomotaurine, Monolithium Salt

    15. N Acetylhomotaurine, Monopotassium Salt

    16. N Acetylhomotaurine, Monosodium Salt

    17. N-acetylhomotaurine

    18. N-acetylhomotaurine, Calcium (2:1) Salt

    19. N-acetylhomotaurine, Magnesium (2:1) Salt

    20. N-acetylhomotaurine, Monolithium Salt

    21. N-acetylhomotaurine, Monopotassium Salt

    22. N-acetylhomotaurine, Monosodium Salt

    23. N-acetylhomotaurine, Zinc (2:1) Salt

    24. Regtect

    25. Sodium Acetylhomotaurine

    26. Zulex

    2.3.2 Depositor-Supplied Synonyms

    1. 77337-73-6

    2. Campral

    3. Campral Ec

    4. Alcomed

    5. Sobriol

    6. Aotal

    7. Calcium 3-acetamidopropane-1-sulfonate

    8. Calcium Acetylhomotaurinate

    9. Acamprosate Calcium [usan]

    10. Calcium N-acetylhomotaurinate

    11. Calcium 3-(acetylamino)propane-1-sulfonate

    12. 1-propanesulfonic Acid, 3-(acetylamino)-, Calcium Salt (2:1)

    13. Acamprosate (calcium)

    14. Nsc-759186

    15. Chebi:51042

    16. Sn-102

    17. 59375n1d0u

    18. Calcium Bis(3-acetamidopropane-1-sulfonate)

    19. Dsstox_cid_27529

    20. Dsstox_rid_82399

    21. Dsstox_gsid_47529

    22. 77337-73-6 (calcium Salt); 77337-76-9 (free Acid).

    23. Calcium Acamprosate

    24. Cas-77337-73-6

    25. Calcium(2+) 3-(acetylamino)propanesulphonate

    26. Ncgc00167462-01

    27. Einecs 278-665-3

    28. N-acetylhomotaurine Calcium

    29. Unii-59375n1d0u

    30. Campral (tn)

    31. Regtect (tn)

    32. Calcium;3-acetamidopropane-1-sulfonate

    33. Calcium 3-(acetylamino)propanesulphonate

    34. Acamprosate Calcium- Bio-x

    35. Schembl137771

    36. 3-(acetylamino)-1-propanesulfonic Acid Calcium Salt

    37. Acamprosate Calcium [mi]

    38. Chembl2068724

    39. Dtxsid6047529

    40. Acamprosate Calcium (jan/usan)

    41. Acamprosate Calcium [jan]

    42. Hms3264j11

    43. Hms3713l22

    44. Pharmakon1600-01505711

    45. Acamprosate Calcium [mart.]

    46. Tox21_112466

    47. Tox21_302606

    48. Acamprosate Calcium [usp-rs]

    49. Acamprosate Calcium [who-dd]

    50. Mfcd00886588

    51. Nsc759186

    52. Akos015895192

    53. Ab07649

    54. Ac-5599

    55. Calcium 3-acetamido-1-propanesulfonate

    56. Ccg-213526

    57. Ks-5292

    58. Nsc 759186

    59. Acamprosate Calcium [orange Book]

    60. Ncgc00256899-01

    61. Acamprosate Calcium [ep Monograph]

    62. Ba164134

    63. Acamprosate Calcium [usp Monograph]

    64. Db-056209

    65. Ft-0621712

    66. 3-acetamido-1-propanesulfonate Calcium

    67. 3-acetamido-1-propanesulphonate Calcium

    68. D02780

    69. T71327

    70. 3-acetamido-1-propanesulfonic Acid Calcium Salt

    71. A839056

    72. Calcium 3-(acetylamino)propane-1-sulphonate

    73. Q27122289

    74. 3-(acetylamino)-1-propanesulfonic Acid Hemicalcium Salt

    75. Z1696861853

    76. 5-methoxy-2-methyl-1-propyl-1h-indole-3-carboxylicacid

    77. 1-propanesulfonic Acid, 3-(acetylamino)-, Calcium Salt (2:1)

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 400.5 g/mol
    Molecular Formula C10H20CaN2O8S2
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count6
    Exact Mass400.0286988 g/mol
    Monoisotopic Mass400.0286988 g/mol
    Topological Polar Surface Area189 Ų
    Heavy Atom Count23
    Formal Charge0
    Complexity202
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count3
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameAcamprosate calcium
    Drug LabelCampral (acamprosate calcium) is supplied in an enteric-coated tablet for oral administration. Acamprosate calcium is a synthetic compound with a chemical structure similar to that of the endogenous amino acid homotaurine, which is a structural analo...
    Active IngredientAcamprosate calcium
    Dosage FormTablet, delayed release
    RouteOral
    Strength333mg
    Market StatusPrescription
    CompanyMylan Pharms; Glenmark Generics; Barr Labs Div Teva

    2 of 2  
    Drug NameAcamprosate calcium
    Drug LabelCampral (acamprosate calcium) is supplied in an enteric-coated tablet for oral administration. Acamprosate calcium is a synthetic compound with a chemical structure similar to that of the endogenous amino acid homotaurine, which is a structural analo...
    Active IngredientAcamprosate calcium
    Dosage FormTablet, delayed release
    RouteOral
    Strength333mg
    Market StatusPrescription
    CompanyMylan Pharms; Glenmark Generics; Barr Labs Div Teva

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Alcohol Deterrents

    Substances interfering with the metabolism of ethyl alcohol, causing unpleasant side effects thought to discourage the drinking of alcoholic beverages. Alcohol deterrents are used in the treatment of alcoholism. (See all compounds classified as Alcohol Deterrents.)

    API Reference Price

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RIVOLTANA Km 6\/7 20053 RODANO (MI) SDNF Italy","customerAddress":"564\/A\/22, ROAD NO.92"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1735151400,"product":"ACAMPROSATE CALCIUM 30 ACAMPROSATE CALCIUM 30","address":"564\/A\/22, ROAD NO.92","city":"HYDERABAD,ANDHRA PRADESH","supplier":"ANGELINI PHARMA","supplierCountry":"ITALY","foreign_port":"ANCONA","customer":"VIATRIS","customerCountry":"INDIA","quantity":"1414.20","actualQuantity":"1414.2","unit":"KGS","unitRateFc":"320","totalValueFC":"479339.1","currency":"EUR","unitRateINR":"28800","date":"26-Dec-2024","totalValueINR":"40728960","totalValueInUsd":"479339.1","indian_port":"Bombay Air","hs_no":"29241900","bill_no":"7455963","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"ANCONA","supplierAddress":"Viale Amelia, 70 00181 Roma - Italy SDNF SDNF Italy","customerAddress":"564\/A\/22, ROAD NO.92"}]
    18-Jan-2021
    26-Dec-2024
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    ABOUT THIS PAGE

    Acamprosate Calcium Manufacturers

    A Acamprosate Calcium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Acamprosate Calcium, including repackagers and relabelers. The FDA regulates Acamprosate Calcium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Acamprosate Calcium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Acamprosate Calcium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Acamprosate Calcium Suppliers

    A Acamprosate Calcium supplier is an individual or a company that provides Acamprosate Calcium active pharmaceutical ingredient (API) or Acamprosate Calcium finished formulations upon request. The Acamprosate Calcium suppliers may include Acamprosate Calcium API manufacturers, exporters, distributors and traders.

    click here to find a list of Acamprosate Calcium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Acamprosate Calcium USDMF

    A Acamprosate Calcium DMF (Drug Master File) is a document detailing the whole manufacturing process of Acamprosate Calcium active pharmaceutical ingredient (API) in detail. Different forms of Acamprosate Calcium DMFs exist exist since differing nations have different regulations, such as Acamprosate Calcium USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Acamprosate Calcium DMF submitted to regulatory agencies in the US is known as a USDMF. Acamprosate Calcium USDMF includes data on Acamprosate Calcium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Acamprosate Calcium USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Acamprosate Calcium suppliers with USDMF on PharmaCompass.

    Acamprosate Calcium KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Acamprosate Calcium Drug Master File in Korea (Acamprosate Calcium KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Acamprosate Calcium. The MFDS reviews the Acamprosate Calcium KDMF as part of the drug registration process and uses the information provided in the Acamprosate Calcium KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Acamprosate Calcium KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Acamprosate Calcium API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Acamprosate Calcium suppliers with KDMF on PharmaCompass.

    Acamprosate Calcium CEP

    A Acamprosate Calcium CEP of the European Pharmacopoeia monograph is often referred to as a Acamprosate Calcium Certificate of Suitability (COS). The purpose of a Acamprosate Calcium CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Acamprosate Calcium EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Acamprosate Calcium to their clients by showing that a Acamprosate Calcium CEP has been issued for it. The manufacturer submits a Acamprosate Calcium CEP (COS) as part of the market authorization procedure, and it takes on the role of a Acamprosate Calcium CEP holder for the record. Additionally, the data presented in the Acamprosate Calcium CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Acamprosate Calcium DMF.

    A Acamprosate Calcium CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Acamprosate Calcium CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Acamprosate Calcium suppliers with CEP (COS) on PharmaCompass.

    Acamprosate Calcium WC

    A Acamprosate Calcium written confirmation (Acamprosate Calcium WC) is an official document issued by a regulatory agency to a Acamprosate Calcium manufacturer, verifying that the manufacturing facility of a Acamprosate Calcium active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Acamprosate Calcium APIs or Acamprosate Calcium finished pharmaceutical products to another nation, regulatory agencies frequently require a Acamprosate Calcium WC (written confirmation) as part of the regulatory process.

    click here to find a list of Acamprosate Calcium suppliers with Written Confirmation (WC) on PharmaCompass.

    Acamprosate Calcium NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Acamprosate Calcium as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Acamprosate Calcium API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Acamprosate Calcium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Acamprosate Calcium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Acamprosate Calcium NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Acamprosate Calcium suppliers with NDC on PharmaCompass.

    Acamprosate Calcium GMP

    Acamprosate Calcium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Acamprosate Calcium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Acamprosate Calcium GMP manufacturer or Acamprosate Calcium GMP API supplier for your needs.

    Acamprosate Calcium CoA

    A Acamprosate Calcium CoA (Certificate of Analysis) is a formal document that attests to Acamprosate Calcium's compliance with Acamprosate Calcium specifications and serves as a tool for batch-level quality control.

    Acamprosate Calcium CoA mostly includes findings from lab analyses of a specific batch. For each Acamprosate Calcium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Acamprosate Calcium may be tested according to a variety of international standards, such as European Pharmacopoeia (Acamprosate Calcium EP), Acamprosate Calcium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Acamprosate Calcium USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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