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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

11 API Suppliers, 3 EU WC, 7 KDMF, 10 Listed Suppliers, $ API Reference Price

11 API Suppliers
3 EU WC
7 KDMF
10 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

19 FDF Dossiers, 6 Europe, 13 Listed Dossiers

19 FDF Dossiers
6 Europe
13 Listed Dossiers

GLOBAL SALES INFORMATION

6 Finished Drug Prices

globalSalesInformation
6 Finished Drug Prices

MARKET PLACE

13 APIs, 1 FDF Dossiers

marketPlace
13 APIs
1 FDF Dossiers

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Ambroxol acefyllinate, Ambromucil, Broncomnes, Surfolase, 96989-76-3, Ambroxol theophyllinacetate

Molecular Formula

C₂₂H₂₈Br₂N₆O₅

Molecular Weight

616.3 g/mol

InChI Key

IPUHJDQWESJTGD-UHFFFAOYSA-N

FDA UNII

0HM1E174TN

1 2D Structure

Acebrophylline

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetic acid

2.1.2 InChI

InChI=1S/C13H18Br2N2O.C9H10N4O4/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;1-11-7-6(8(16)12(2)9(11)17)13(4-10-7)3-5(14)15/h5-6,10-11,17-18H,1-4,7,16H2;4H,3H2,1-2H3,(H,14,15)

2.1.3 InChI Key

IPUHJDQWESJTGD-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN1C2=C(C(=O)N(C1=O)C)N(C=N2)CC(=O)O.C1CC(CCC1NCC2=C(C(=CC(=C2)Br)Br)N)O

2.2 Other Identifiers

2.2.1 UNII

0HM1E174TN

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Ambroxol-theophylline-7-acetate

2.3.2 Depositor-Supplied Synonyms

1. Ambroxol Acefyllinate

2. Ambromucil

3. Broncomnes

4. Surfolase

5. 96989-76-3

6. Ambroxol Theophyllinacetate

7. 179118-73-1

8. Ambroxol-theophylline-7-acetate

9. Ambroxol Theophyllinate

10. 0hm1e174tn

11. 4-[(2-amino-3,5-dibromophenyl)methylamino]cyclohexan-1-ol;2-(1,3-dimethyl-2,6-dioxopurin-7-yl)acetic Acid

12. Cyclohexanol, 4-(((2-amino-3,5-dibromophenyl)methyl)amino)-, Trans-, Mono(1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7h-purine-7-acetate) (salt)

13. Unii-0hm1e174tn

14. Schembl1650322

15. Chembl4297663

16. Dtxsid60914235

17. Glxc-26022

18. Bcp28655

19. Ambroxol Acefyllinate [mart.]

20. Akos015899892

21. Ambroxol Acefyllinate [who-dd]

22. Db13141

23. Ambroxol Theophyllinate [who-dd]

24. Ambromucil Pound>>ambroxol-theophylline-7-acetate

25. Q19607226

26. (1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7h-purin-7-yl)acetic Acid--4-{[(2-amino-3,5-dibromophenyl)methyl]amino}cyclohexan-1-ol (1/1)

27. 7h-purine-7-acetic Acid, 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-, Compd. With Trans-4-(((2-amino-3,5-dibromophenyl)methyl)amino)cyclohexanol (1:1)

2.4 Create Date

2005-08-09

3 Chemical and Physical Properties

Molecular Formula	C₂₂H₂₈Br₂N₆O₅
Molecular Weight	616.3 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	5
Exact Mass	616.04674 g/mol
Monoisotopic Mass	614.04879 g/mol
Topological Polar Surface Area	154 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	645
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

API SUPPLIERS

01

Ami Lifesciences Private Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

AMI Lifesciences is Driven by Chemistry. Powered by People.

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India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC

NDC KDMF

VMF MX

AUDIT

02

Bakul Group

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

03

Globofarm International

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

04

Atomgrid

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

05

Delta Finochem

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

06

S.S.Pharmachem

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

07

Olon S.p.A

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

08

Hermes Chemical

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

09

Aspire Lifesciences Pvt Ltd

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

10

Kores India Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Medlab Asia & Asia Health

Not Confirmed

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EU WC

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KDMF

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Listed Suppliers

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API Reference Price

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