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1. 83-32-9
2. 1,2-dihydroacenaphthylene
3. 1,8-ethylenenaphthalene
4. Peri-ethylenenaphthalene
5. Naphthyleneethylene
6. Acenaphthylene, 1,2-dihydro-
7. Ethylenenaphthalene
8. 1,8-dihydroacenaphthalene
9. V8ut1gac5y
10. Chebi:22154
11. Nsc-7657
12. Mfcd00003807
13. Dsstox_cid_1774
14. Dsstox_rid_76319
15. Dsstox_gsid_21774
16. Cas-83-32-9
17. Ccris 5951
18. Hsdb 2659
19. Nsc 7657
20. Einecs 201-469-6
21. Unii-v8ut1gac5y
22. 1,2-dihydro Acenaphthylene
23. Ai3-00128
24. Acenaphthene, 97%
25. Acenaphthene, 99%
26. Acenaphthene,
27. Acenaphthene [mi]
28. Acenaphthene [hsdb]
29. Acenaphthene [iarc]
30. Ec 201-469-6
31. Naphthalene, 1,8-ethylene-
32. Bidd:gt0787
33. Chembl1797271
34. Dtxsid3021774
35. Acenaphthene, Analytical Standard
36. Nsc7657
37. Zinc1235986
38. Tox21_202400
39. Tox21_300013
40. Stl483068
41. Akos000119983
42. Fs-4341
43. Acenaphthene 100 Microg/ml In Methanol
44. Ncgc00163966-01
45. Ncgc00163966-02
46. Ncgc00163966-03
47. Ncgc00163966-04
48. Ncgc00254079-01
49. Ncgc00259949-01
50. Ac-19767
51. Acenaphthene 10 Microg/ml In Acetonitrile
52. Acenaphthene 100 Microg/ml In Acetonitrile
53. Db-056708
54. A0003
55. A0135
56. Acenaphthene 1000 Microg/ml In Acetonitrile
57. Ft-0621716
58. C19312
59. D97698
60. Acenaphthene Zone Refined (number Of Passes:30)
61. Q415103
62. W-104147
63. Z56926550
64. 73bcd470-1e93-4e76-bf03-e06fb8fe00ea
65. Acenaphthene, Certified Reference Material, Tracecert(r)
66. F1908-0103
67. Acenaphthene Solution, 100 Mug/ml In Cyclohexane, Analytical Standard
68. Acenaphthene Solution, Certified Reference Material, 200 Mug/ml In Methanol
| Molecular Weight | 154.21 g/mol |
|---|---|
| Molecular Formula | C12H10 |
| XLogP3 | 3.9 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 0 |
| Rotatable Bond Count | 0 |
| Exact Mass | 154.078250319 g/mol |
| Monoisotopic Mass | 154.078250319 g/mol |
| Topological Polar Surface Area | 0 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 155 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
The waxy surface of some plant leaves and fruits can concentrate polyaromatic hydrocarbons through surface adsorption. /Polynuclear aromatic hydrocarbons/
USEPA; Ambient Water Quality Criteria Doc: Polynuclear Aromatic Hydrocarbons p.C-11 (1980)
The filamentous fungus Cunninghamella elegans ATCC 36112 metabolized within 72 hr of incubation approximately 64% of the [1,8-(14)C]acenaphthene added. The radioactive metabolites were extracted with ethyl acetate and separated by thin-layer chromatography and reversed-phase high-performance liquid chromatography. Seven metabolites were identified by 1H nuclear magnetic resonance, UV, and mass spectral techniques as 6-hydroxyacenaphthenone (24.8%), 1,2-acenaphthenedione (19.9%), trans-1,2-dihydroxyacenaphthene (10.3%), 1,5-dihydroxyacenaphthene (2.7%), 1-acenaphthenol (2.4%), 1-acenaphthenone (2.1%), and cis-1,2-dihydroxyacenaphthene (1.8%). Parallel experiments with rat liver microsomes indicated that the major metabolite formed from acenaphthene by rat liver microsomes was 1-acenaphthenone. The fungal metabolism of acenaphthene was similar to bacterial and mammalian metabolism, since the primary site of enzymatic attack was on the two carbons of the five-member ring.
PMID:1482186 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC183157 Pothuluri JV et al; Appl Environ Microbiol 58 (11): 3654-9 (1992)
Metabolized to naphthalene-1,8-dicarboxylic acid in rats. /From table/
Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-1
... Possibility of limited metabolism of acenaphthene to naphthalic acid and naphthalic anhydride.
Acenaphthene; pp 46-7 in Priority Toxic Pollutants; Sittig M, ED (1980)
A Beijerinckia species and a mutant strain, Beijerinckia species strain B8/36, were shown to oxidize the polycyclic aromatic hydrocarbons acenaphthene and acenaphthylene. Both organisms oxidized acenaphthene to the same spectrum of metabolites, which included 1-acenaphthenol, 1-acenaphtheneone, 1,2-acenaphthenediol, acenaphthenequinone, and a compound that was tentatively identified as 1,2-dihydroxyacenaphthylene. In contrast, acenaphthylene was oxidized to acenaphthenequinone and the compound tentatively identified as 1,2-dihydroxyacenaphthylene was also formed when the organism was incubated with synthetic cis-1,2-acenaphthenediol. A metabolite identified as cis-1,2-acenaphthenediol was formed from acenaphthylene by the mutant Beijerinckia species strain B8/36. Cell extracts prepared from the wild-type Beijerinckia strain contain a constitutive pyridine nucleotide-dependent dehydrogenase which can oxidize 1-acenaphthenol and 9-fluorenol. The results indicate that although acenaphthene and acenaphthylene are both oxidized to acenaphthenequinone, the pathways leading to the formation of this end product are different.
PMID:6089663 Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC240288 Schocken MJ, Gibson DT; Appl Environ Microbiol 48 (1): 10-16 (1984)
For more Metabolism/Metabolites (Complete) data for ACENAPHTHENE (7 total), please visit the HSDB record page.
The half-life of acenaphthene in /the bluegill fish/ is less than 1 day.
USEPA; Ambient Water Quality Criteria Doc: Acenaphthene (Draft) p.B-2 (1980)
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A Acenaphthene manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Acenaphthene, including repackagers and relabelers. The FDA regulates Acenaphthene manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Acenaphthene API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Acenaphthene supplier is an individual or a company that provides Acenaphthene active pharmaceutical ingredient (API) or Acenaphthene finished formulations upon request. The Acenaphthene suppliers may include Acenaphthene API manufacturers, exporters, distributors and traders.
Acenaphthene Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Acenaphthene GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Acenaphthene GMP manufacturer or Acenaphthene GMP API supplier for your needs.
A Acenaphthene CoA (Certificate of Analysis) is a formal document that attests to Acenaphthene's compliance with Acenaphthene specifications and serves as a tool for batch-level quality control.
Acenaphthene CoA mostly includes findings from lab analyses of a specific batch. For each Acenaphthene CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Acenaphthene may be tested according to a variety of international standards, such as European Pharmacopoeia (Acenaphthene EP), Acenaphthene JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Acenaphthene USP).
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