Find Aconiazide manufacturers, exporters & distributors on PharmaCompass

Aconiazide

Seqens is an integrated global leader in pharmaceutical solutions & specialty ingredients & provides custom-made solutions.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 USDMF

2 API Suppliers
2 USDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Aconiazide, Ncgc00160674-01, {2-[(e)-(isonicotinoylhydrazono)methyl]phenoxy}acetic acid, Aconiazide [inn], 8okq9ns8mo, 13410-86-1

Molecular Formula

C₁₅H₁₃N₃O₄

Molecular Weight

299.28 g/mol

InChI Key

MDFXJBQEWLCGHP-RQZCQDPDSA-N

FDA UNII

8OKQ9NS8MO

Aconiazide is a hydrazone derivative of isoniazid, used in the treatment and prophylaxis of tuberculosis.

1 2D Structure

Aconiazide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[2-[(E)-(pyridine-4-carbonylhydrazinylidene)methyl]phenoxy]acetic acid

2.1.2 InChI

InChI=1S/C15H13N3O4/c19-14(20)10-22-13-4-2-1-3-12(13)9-17-18-15(21)11-5-7-16-8-6-11/h1-9H,10H2,(H,18,21)(H,19,20)/b17-9+

2.1.3 InChI Key

MDFXJBQEWLCGHP-RQZCQDPDSA-N

2.1.4 Canonical SMILES

C1=CC=C(C(=C1)C=NNC(=O)C2=CC=NC=C2)OCC(=O)O

2.1.5 Isomeric SMILES

C1=CC=C(C(=C1)/C=N/NC(=O)C2=CC=NC=C2)OCC(=O)O

2.2 Other Identifiers

2.2.1 UNII

8OKQ9NS8MO

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2-formylphenoxyacetic Acid Isonicotinylhydrazone

2. Aconiazide

2.3.2 Depositor-Supplied Synonyms

1. Aconiazide

2. Ncgc00160674-01

3. {2-[(e)-(isonicotinoylhydrazono)methyl]phenoxy}acetic Acid

4. Aconiazide [inn]

5. 8okq9ns8mo

6. 13410-86-1

7. Aconiazide [mart.]

8. Dsstox_cid_26292

9. Dsstox_rid_81518

10. Dsstox_gsid_46292

11. Schembl635283

12. Chembl1590674

13. Dtxsid8046292

14. Tox21_111977

15. Stk181710

16. Akos001031966

17. Cas-13410-86-1

18. Sr-01000872617

19. Sr-01000872617-2

20. Isonicotinic Acid (2-(carboxymethoxy)benzylidene)hydrazide

21. 2-(2-{[2-(4-pyridylcarbonyl)hydrazinylidene]methyl}phenoxy)acetic Acid

22. (2-{(e)-[2-(pyridin-4-ylcarbonyl)hydrazinylidene]methyl}phenoxy)acetic Acid

2.4 Create Date

2006-04-28

3 Chemical and Physical Properties

Molecular Formula	C₁₅H₁₃N₃O₄
Molecular Weight	299.28 g/mol
XLogP3	1.3
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	299.09060590 g/mol
Monoisotopic Mass	299.09060590 g/mol
Topological Polar Surface Area	101 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	408
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antitubercular Agents

Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy. (See all compounds classified as Antitubercular Agents.)

API SUPPLIERS