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Chemistry

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Also known as: 1266084-51-8, Scyx-7158, 4-fluoro-n-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-2-(trifluoromethyl)benzamide, 2ior2oo3gw, 4-fluoro-n-(1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-2-(trifluoromethyl)benzamide, 4-fluoro-n-(1-hydroxy-3,3-dimethyl-1,3-dihydro-benzo(c)(1),(2)oxaborol-6-yl-2-trifluoromethyl benzamide
Molecular Formula
C17H14BF4NO3
Molecular Weight
367.1  g/mol
InChI Key
PTYGDEXEGLDNAZ-UHFFFAOYSA-N
FDA UNII
2IOR2OO3GW

Acoziborole
SCYX-7158 has been used in trials studying the treatment of Trypanosomiasis, Parasitic Diseases, Protozoan Infections, and Trypanosomiasis, African.
1 2D Structure

Acoziborole

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-fluoro-N-(1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-2-(trifluoromethyl)benzamide
2.1.2 InChI
InChI=1S/C17H14BF4NO3/c1-16(2)12-6-4-10(8-14(12)18(25)26-16)23-15(24)11-5-3-9(19)7-13(11)17(20,21)22/h3-8,25H,1-2H3,(H,23,24)
2.1.3 InChI Key
PTYGDEXEGLDNAZ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
B1(C2=C(C=CC(=C2)NC(=O)C3=C(C=C(C=C3)F)C(F)(F)F)C(O1)(C)C)O
2.2 Other Identifiers
2.2.1 UNII
2IOR2OO3GW
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Scyx 7158

2. Scyx-7158

3. Scyx7158

2.3.2 Depositor-Supplied Synonyms

1. 1266084-51-8

2. Scyx-7158

3. 4-fluoro-n-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-2-(trifluoromethyl)benzamide

4. 2ior2oo3gw

5. 4-fluoro-n-(1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-2-(trifluoromethyl)benzamide

6. 4-fluoro-n-(1-hydroxy-3,3-dimethyl-1,3-dihydro-benzo(c)(1),(2)oxaborol-6-yl-2-trifluoromethyl Benzamide

7. Benzamide, N-(1,3-dihydro-1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-4-fluoro-2-(trifluoromethyl)-

8. Unii-2ior2oo3gw

9. Acoziborole [inn]

10. Acoziborole [who-dd]

11. Schembl1164186

12. Chembl2347704

13. Sctx-7158

14. Chebi:183111

15. Dtxsid301336035

16. An5568

17. Mfcd30532746

18. Akos037644970

19. Db13086

20. 4-fluoro-n-(1-hydroxy-3,3-dimethyl-1,3-dihydro-2,1-benzoxaborol-6-yl)-2-(trifluoromethyl)benzamide

21. Ac-36374

22. As-55745

23. Hy-19910

24. Cs-0016944

25. J3.511.276f

26. W19688

27. A937430

28. Q27254793

29. 4-luoro-n-(1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-2-(triluoromethyl)benzamide

30. 4-fluoro-n-(1-hydroxy-3,3-dimethyl-1,3-dihydro-benzo[c][1,2]oxaborol-6-yl)-2-trifluoromethyl Benzamide

31. N-(1,3-dihydro-1-hydroxy-3,3-dimethyl-2,1-benzoxaborol-6-yl)-4-fluoro-2-(trifluoromethyl)benzamide

2.4 Create Date
2009-08-31
3 Chemical and Physical Properties
Molecular Weight 367.1 g/mol
Molecular Formula C17H14BF4NO3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count2
Exact Mass367.1002861 g/mol
Monoisotopic Mass367.1002861 g/mol
Topological Polar Surface Area58.6 Ų
Heavy Atom Count26
Formal Charge0
Complexity545
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Acoziborole Manufacturers

A Acoziborole manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Acoziborole, including repackagers and relabelers. The FDA regulates Acoziborole manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Acoziborole API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Acoziborole Suppliers

A Acoziborole supplier is an individual or a company that provides Acoziborole active pharmaceutical ingredient (API) or Acoziborole finished formulations upon request. The Acoziborole suppliers may include Acoziborole API manufacturers, exporters, distributors and traders.

Acoziborole GMP

Acoziborole Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Acoziborole GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Acoziborole GMP manufacturer or Acoziborole GMP API supplier for your needs.

Acoziborole CoA

A Acoziborole CoA (Certificate of Analysis) is a formal document that attests to Acoziborole's compliance with Acoziborole specifications and serves as a tool for batch-level quality control.

Acoziborole CoA mostly includes findings from lab analyses of a specific batch. For each Acoziborole CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Acoziborole may be tested according to a variety of international standards, such as European Pharmacopoeia (Acoziborole EP), Acoziborole JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Acoziborole USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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