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Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

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PATENTS & EXCLUSIVITIES

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Chemistry

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Also known as: Verbascoside, Kusaginin, 61276-17-3, Tjc 160, Acetoside, Verbacoside

Molecular Formula

C₂₉H₃₆O₁₅

Molecular Weight

624.6 g/mol

InChI Key

FBSKJMQYURKNSU-ZLSOWSIRSA-N

FDA UNII

3TGX09BD5B

verbascoside is a natural product found in Orobanche amethystea, Barleria lupulina, and other organisms with data available.

1 2D Structure

Acteoside

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

[(2R,3R,4R,5R,6R)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

2.1.2 InChI

InChI=1S/C29H36O15/c1-13-22(36)23(37)24(38)29(41-13)44-27-25(39)28(40-9-8-15-3-6-17(32)19(34)11-15)42-20(12-30)26(27)43-21(35)7-4-14-2-5-16(31)18(33)10-14/h2-7,10-11,13,20,22-34,36-39H,8-9,12H2,1H3/b7-4+/t13-,20+,22-,23+,24+,25+,26+,27+,28+,29-/m0/s1

2.1.3 InChI Key

FBSKJMQYURKNSU-ZLSOWSIRSA-N

2.1.4 Canonical SMILES

CC1C(C(C(C(O1)OC2C(C(OC(C2OC(=O)C=CC3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O

2.1.5 Isomeric SMILES

C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@H]2OC(=O)/C=C/C3=CC(=C(C=C3)O)O)CO)OCCC4=CC(=C(C=C4)O)O)O)O)O)O

2.2 Other Identifiers

2.2.1 UNII

3TGX09BD5B

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-o-(6-deoxy-alpha-l-mannopyranosyl)-, 4-(3-(3,4-dihydroxyphenyl)-2-propenoate), (e)-beta-d-

2. Kusaginin

3. Tjc 160

4. Tjc-160

5. Verbascoside

2.3.2 Depositor-Supplied Synonyms

1. Verbascoside

2. Kusaginin

3. 61276-17-3

4. Tjc 160

5. Acetoside

6. Verbacoside

7. Nsc 603831

8. 3tgx09bd5b

9. Mfcd00221751

10. [(2r,3r,4r,5r,6r)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-tetrahydropyran-3-yl] (e)-3-(3,4-dihydroxyphenyl)prop-2-enoate

11. 22323-52-0

12. Tjc-160

13. Unii-3tgx09bd5b

14. Nsc-603831

15. .beta.-d-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-o-(6-deoxy-.alpha.-l-mannopyranosyl)-, 4-((2e)-3-(3,4-dihydroxyphenyl)-2-propenoate)

16. .beta.-d-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-o-(6-deoxy-.alpha.-l-mannopyranosyl)-, 4-[(2e)-3-(3,4-dihydroxyphenyl)-2-propenoate]

17. Russetinol

18. Stereospermin

19. Acteoside; Verbascoside

20. Verbascoside [inci]

21. Glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-o-(6-deoxy-alpha-l-mannopyranosyl)-, 4-(3-(3,4-dihydroxyphenyl)-2-propenoate), (e)-beta-d-

22. Mls002473233

23. Schembl657970

24. Verbascoside [usp-rs]

25. Chebi:9953

26. Chembl231853

27. Chembl444478

28. Tjc160

29. Cid_5281800

30. Verbascoside, >=99% (hplc)

31. Chebi:132853

32. Cid_24978601

33. Dtxsid701021953

34. Hms2205k11

35. Hy-n0021

36. Zinc8234351

37. Bdbm50241867

38. S5458

39. Akos015897165

40. Ccg-270269

41. Db12996

42. Ncgc00378687-03

43. As-75167

44. Smr001397320

45. N1341

46. 276a173

47. B864379

48. Q411426

49. Q-100706

50. Verbascoside, Primary Pharmaceutical Reference Standard

51. Verbascoside, United States Pharmacopeia (usp) Reference Standard

52. ((2r,3r,4r,5r,6r)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yloxy)tetrahydro-2h-pyran-3-yl) 3-(3,4-dihydroxyphenyl)acrylate

53. ((2r,3r,4r,5r,6r)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-((2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yloxy)tetrahydro-2h-pyran-3-yl)3-(3,4-dihydroxyphenyl)acrylate

54. (2r,3r,4r,5r,6r)-6-(3,4-dihydroxyphenethoxy)-5-hydroxy-2-(hydroxymethyl)-4-(((2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yl)oxy)tetrahydro-2h-pyran-3-yl (e)-3-(3,4-dihydroxyphenyl)acrylate

55. (2r,3r,4r,5r,6r)-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-2-(hydroxymethyl)-4-{[(2s,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}oxan-3-yl (2e)-3-(3,4-dihydroxyphenyl)prop-2-enoate

56. (3,4-dihydroxyphenyl)ethyl O-.alpha.-rhamnopyranosyl(1->3)-4-o-caffeoyl-.beta.-d Glucopyranoside

57. .beta.-d-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl3-o-(6-deoxy-.alpha.-l-mannopyranosyl)-, 4-[(2e)-3-(3,4-dihydroxyphenyl)-2-propenoate]

58. 2-(3,4-dihydroxyphenyl)ethyl 3-o-(6-deoxy-alpha-l-mannopyranosyl)-4-o-[(2e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-d-glucopyranoside

59. 2-(3,4-dihydroxyphenyl)ethyl 3-o-(alpha-l-rhamnopyranosyl)-4-o-[(2e)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]-beta-d-glucopyranoside

60. 3,4-dihydroxyphenethyl 3-o-alpha-l-rhamnopyranosyl-4-o-[3-(3,4-dihydroxyphenyl)acryloyl]-beta-d-glucopyranoside

61. Beta-d-glucopyranoside, 2-(3,4-dihydroxyphenyl)ethyl 3-o-(6-deoxy-alpha-l-mannopyranosyl)-, 4-[(2e)-3-(3,4-dihydroxyphenyl)-2-propenoate]

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₉H₃₆O₁₅
Molecular Weight	624.6 g/mol
XLogP3	-0.5
Hydrogen Bond Donor Count	9
Hydrogen Bond Acceptor Count	15
Rotatable Bond Count	11
Exact Mass	624.20542044 g/mol
Monoisotopic Mass	624.20542044 g/mol
Topological Polar Surface Area	245 Å²
Heavy Atom Count	44
Formal Charge	0
Complexity	936
Isotope Atom Count	0
Defined Atom Stereocenter Count	10
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Immunosuppressive Agents

Agents that suppress immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-CELLS or by inhibiting the activation of HELPER CELLS. While immunosuppression has been brought about in the past primarily to prevent rejection of transplanted organs, new applications involving mediation of the effects of INTERLEUKINS and other CYTOKINES are emerging. (See all compounds classified as Immunosuppressive Agents.)

Antineoplastic Agents, Phytogenic

Agents obtained from higher plants that have demonstrable cytostatic or antineoplastic activity. (See all compounds classified as Antineoplastic Agents, Phytogenic.)

Chelating Agents

Chemicals that bind to and remove ions from solutions. Many chelating agents function through the formation of COORDINATION COMPLEXES with METALS. (See all compounds classified as Chelating Agents.)

Anti-Infective Agents

Substances that prevent infectious agents or organisms from spreading or kill infectious agents in order to prevent the spread of infection. (See all compounds classified as Anti-Infective Agents.)

Antioxidants

Naturally occurring or synthetic substances that inhibit or retard oxidation reactions. They counteract the damaging effects of oxidation in animal tissues. (See all compounds classified as Antioxidants.)

REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

Acteoside Manufacturers

A Acteoside manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Acteoside, including repackagers and relabelers. The FDA regulates Acteoside manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Acteoside API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Acteoside Suppliers

A Acteoside supplier is an individual or a company that provides Acteoside active pharmaceutical ingredient (API) or Acteoside finished formulations upon request. The Acteoside suppliers may include Acteoside API manufacturers, exporters, distributors and traders.

Acteoside GMP

Acteoside Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Acteoside GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Acteoside GMP manufacturer or Acteoside GMP API supplier for your needs.

Acteoside CoA

A Acteoside CoA (Certificate of Analysis) is a formal document that attests to Acteoside's compliance with Acteoside specifications and serves as a tool for batch-level quality control.

Acteoside CoA mostly includes findings from lab analyses of a specific batch. For each Acteoside CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Acteoside may be tested according to a variety of international standards, such as European Pharmacopoeia (Acteoside EP), Acteoside JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Acteoside USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.