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    Chemistry

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    Also known as: 64-75-5, Tetracycline hcl, Achromycin hydrochloride, Bristacycline, Sustamycin, Tetracycline.hcl
    Molecular Formula
    C22H25ClN2O8
    Molecular Weight
    480.9  g/mol
    InChI Key
    YCIHPQHVWDULOY-FMZCEJRJSA-N
    FDA UNII
    P6R62377KV
    Tetracycline Hydrochloride
    A naphthacene antibiotic that inhibits AMINO ACYL TRNA binding during protein synthesis.
    1 2D Structure

    Tetracycline Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (4S,4aS,5aS,6S,12aR)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride
    2.1.2 InChI
    InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25-26,29,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
    2.1.3 InChI Key
    YCIHPQHVWDULOY-FMZCEJRJSA-N
    2.1.4 Canonical SMILES
    CC1(C2CC3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
    2.1.5 Isomeric SMILES
    C[C@@]1([C@H]2C[C@H]3[C@@H](C(=O)C(=C([C@]3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    P6R62377KV
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 4 Epitetracycline

    2. 4-epitetracycline

    3. Achromycin

    4. Achromycin V

    5. Hostacyclin

    6. Sustamycin

    7. Tetrabid

    8. Tetracycline

    9. Tetracycline Monohydrochloride

    10. Topicycline

    2.3.2 Depositor-Supplied Synonyms

    1. 64-75-5

    2. Tetracycline Hcl

    3. Achromycin Hydrochloride

    4. Bristacycline

    5. Sustamycin

    6. Tetracycline.hcl

    7. Cyclopar

    8. Sumycin

    9. Tetracycline (hydrochloride)

    10. Achromycin V

    11. Neocycline B

    12. Vetquamycin 324

    13. Achromycin

    14. Supramycin

    15. Telotrex

    16. Nci-c55561

    17. Nsc-757338

    18. Quatrex

    19. P6r62377kv

    20. Dumocyclin

    21. (4s,4as,5as,6s,12as)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide Hydrochloride

    22. 64-75-5 (hcl)

    23. Dsstox_cid_1321

    24. Dsstox_rid_76081

    25. Dsstox_gsid_21321

    26. (4s,4as,5as,6s,12as)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrochloride

    27. Hostacycline

    28. Mephacyclin

    29. Quadracycline

    30. Remicyclin

    31. Stilciclina

    32. Tetrabakat

    33. Tetracompren

    34. Tetralution

    35. Tetramavan

    36. Topicycline

    37. Triphacyclin

    38. Actisite

    39. Artomycin

    40. Diacycine

    41. Partrex

    42. Piracaps

    43. Ricycline

    44. Subamycin

    45. Tefilin

    46. Tetrabid

    47. Tetrablet

    48. Tetracaps

    49. Tetrakap

    50. Tetramed

    51. Tetrosol

    52. Paltet

    53. Qidtet

    54. Retet

    55. Teline

    56. Unicin

    57. Tetra-wedel

    58. Neocyclin B

    59. Ro-cycline

    60. Polyotic Ointment

    61. Tetrasure

    62. Tet-cy

    63. Tetra-d

    64. Vetquamycin-324

    65. Cancycline-250

    66. (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

    67. 2-naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride,(4s,4as,5as,6s,12as)-

    68. Cefracycline Tablets

    69. Tetracycline Chloride

    70. Panmycin Hydrochloride

    71. Sentry Av Ornacycline

    72. T-250 Capsules

    73. Tetracyn Hydrochloride

    74. Tetraciclina Cloridrato

    75. Ala Tet

    76. Polycycline Hydrochloride

    77. Chlorowodorku Tetracykliny

    78. Mfcd00078142

    79. Chlorhydrate De Tetracycline

    80. Unii-p6r62377kv

    81. Ccris 2351

    82. Sr-01000000212

    83. Sr-05000001723

    84. (-)-tetrahcycline Hydrochloride

    85. Tetracycline Hydrochloride [jan]

    86. Tetraciclina Cloridrato [italian]

    87. Chlorowodorku Tetracykliny [polish]

    88. (4s,4as,5as,6s,12as)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide;hydrochloride

    89. Prestwick_434

    90. Einecs 200-593-8

    91. Bristacycline (tn)

    92. Chlorhydrate De Tetracycline [french]

    93. Tetracycline Hydrochloride [usp:jan]

    94. Tetracycline Hydrochloride (internal Use)

    95. Ai3-50120

    96. Cas-64-75-5

    97. Ncgc00016291-01

    98. Tetracyclini Hydrochloridum

    99. Ec 200-593-8

    100. U-5965

    101. Schembl34248

    102. Spectrum1500566

    103. Chembl454950

    104. Dtxsid6021321

    105. Nci-c55561;tetracycline Hcl

    106. Tetracycline Hydrochloride, Powder

    107. Hms1568k22

    108. Hms1921c19

    109. Pharmakon1600-01500566

    110. Hy-b0474

    111. Tox21_110355

    112. Tox21_200516

    113. Ccg-39267

    114. Nsc757338

    115. S2574

    116. Akos015951263

    117. Tox21_110355_1

    118. Bcp9000227

    119. Ks-1431

    120. Nsc 757338

    121. Tetracycline Hydrochloride (jp17/usp)

    122. Tetracycline Hydrochloride [mi]

    123. Ncgc00017323-08

    124. Ncgc00180907-01

    125. Ncgc00180907-02

    126. Ncgc00258070-01

    127. (4s,6s,12as,4as,5as)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,1 1-dioxo-4,5,6,12a,4a,5a-hexahydronaphthacene-2-carboxamide, Chloride

    128. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s,4as,5as,6s,12as)-

    129. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s-(4alpha,4aalpha,5aalpha,6beta,12aalpha))-

    130. Tetracycline Hydrochloride [mart.]

    131. Tetracycline Hydrochloride [vandf]

    132. Bcp0726000161

    133. Tetracycline Hydrochloride [usp-rs]

    134. Tetracycline Hydrochloride [who-dd]

    135. Tetracycline Hydrochloride [who-ip]

    136. Sw196293-4

    137. D02122

    138. D92606

    139. Tetracycline Hydrochloride [green Book]

    140. Tetracycline Hydrochloride [orange Book]

    141. Tetracycline Hydrochloride [ep Monograph]

    142. Apt T3x Component Tetracycline Tetracycline

    143. Apt-t3x Component Tetracycline Tetracycline

    144. Helidac Component Tetracycline Hydrochloride

    145. Tetracycline Hydrochloride [usp Monograph]

    146. Tetracyclini Hydrochloridum [who-ip Latin]

    147. Sr-01000000212-4

    148. Sr-05000001723-2

    149. Q27286287

    150. Tetracycline Hydrochloride 1000 Microg/ml In Ethanol

    151. Tetracycline Hydrochloride Component Of Helidac

    152. Tetracycline Tetracycline Component Of Apt T3x

    153. Tetracycline Hydrochloride 100 Microg/ml In Acetonitrile

    154. Tetracycline Hydrochloride, Meets Usp Testing Specifications

    155. Tetracycline Hydrochloride, Vetranal(tm), Analytical Standard

    156. Tetracycline Hydrochloride, >=95% (european Pharmacopoeia Hplc Assay)

    157. Tetracycline Hydrochloride, British Pharmacopoeia (bp) Reference Standard

    158. Tetracycline Hydrochloride, European Pharmacopoeia (ep) Reference Standard

    159. Tetracycline Hydrochloride, Powder, Bioreagent, Suitable For Cell Culture

    160. Tetracycline Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material

    161. Tetracycline Hydrochloride, United States Pharmacopeia (usp) Reference Standard

    162. (4s,4as,5as,6s,12ar)-4-(dimethylamino)-1,6,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-3,4,4a,5,5a,6,12,12a-octahydrotetracene-2-carboxamide Hydrochloride

    163. (4s,4as,5as,6s,12as)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamidehydrochloride

    164. (4s,4as,5as,6s,12as)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4,4a,5,5a-tetrahydrotetracene-2-carboxamide Hydrochloride

    165. (4s,4as,5as,6s,12as,z)-2-(amino(hydroxy)methylene)-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2h,4h,5h)-trione Hydrochloride

    166. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Hydrochloride (1:1), (4s,4as,5as,6s,12as)-

    167. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s-(4.alpha.,4a.alpha.,5a.alpha.,6.beta.,12a.alpha.))-

    168. 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, Monohydrochloride, (4s-(4alpha,4aalpha,5aalpha,6beta,12alpha))-

    2.4 Create Date
    2011-12-26
    3 Chemical and Physical Properties
    Molecular Weight 480.9 g/mol
    Molecular Formula C22H25ClN2O8
    Hydrogen Bond Donor Count7
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count2
    Exact Mass480.1299435 g/mol
    Monoisotopic Mass480.1299435 g/mol
    Topological Polar Surface Area182 Ų
    Heavy Atom Count33
    Formal Charge0
    Complexity971
    Isotope Atom Count0
    Defined Atom Stereocenter Count5
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameTetracycline hydrochloride
    Drug LabelTetracycline is a yellow, odorless, crystalline powder. Tetracycline is stable in air but exposure to strong sunlight causes it to darken. Its potency is affected in solutions of pH below 2 and is rapidly destroyed by alkali hydroxide solutions. Tetr...
    Active IngredientTetracycline hydrochloride
    Dosage FormCapsule
    RouteOral
    Strength250mg; 500mg; 100mg
    Market StatusPrescription
    CompanyWatson Labs; Ivax Sub Teva Pharms; Impax Labs

    2 of 2  
    Drug NameTetracycline hydrochloride
    Drug LabelTetracycline is a yellow, odorless, crystalline powder. Tetracycline is stable in air but exposure to strong sunlight causes it to darken. Its potency is affected in solutions of pH below 2 and is rapidly destroyed by alkali hydroxide solutions. Tetr...
    Active IngredientTetracycline hydrochloride
    Dosage FormCapsule
    RouteOral
    Strength250mg; 500mg; 100mg
    Market StatusPrescription
    CompanyWatson Labs; Ivax Sub Teva Pharms; Impax Labs

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Anti-Bacterial Agents

    Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)

    Protein Synthesis Inhibitors

    Compounds which inhibit the synthesis of proteins. They are usually ANTI-BACTERIAL AGENTS or toxins. Mechanism of the action of inhibition includes the interruption of peptide-chain elongation, the blocking the A site of ribosomes, the misreading of the genetic code or the prevention of the attachment of oligosaccharide side chains to glycoproteins. (See all compounds classified as Protein Synthesis Inhibitors.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Tetracyclines [CS]; Tetracycline-class Antimicrobial [EPC]

    API Reference Price

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ZHANGJIAGANG CITY, JIANGSU, CHINA","customerAddress":"213, LAXMI PLAZA, LAXMI INDL."},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730658600,"product":"OXYTETRACYCLINE HYDROCHLORIDE IP (200 DRM)(LONGCHEM INTERNATIONAL TRADING COMPANY LIMITED) IUPAC NAME: (4S,4AR,5S,5AR,6SOXYTETRACYCLINE HYDROCHLORIDE IP (200 DRM)(LONGCHEM INTERNAT","address":"DARABSHAW HOUSE LEVEL 1 SHOORJI","city":"MUMBAI","supplier":"SHANGHAI FINE CHEMICALS CO.,LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"NHAVA SHEVA BUSINESS PARK PRIVATE LIMITED","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"10.5","totalValueFC":"52849.5","currency":"USD","unitRateINR":"892","date":"04-Nov-2024","totalValueINR":"4459875","totalValueInUsd":"52849.5","indian_port":"JNPT SEZ\/MUMBAI","hs_no":"29413020","bill_no":"6477525","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"RM719, NO.8-9, MAX-MALL, LANE 1500 SOUTH LIANHUA ROAD, SHANGHAI Shangh ai, , CHINA CHINA","customerAddress":"DARABSHAW HOUSE LEVEL 1 SHOORJI"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1730917800,"product":"OXYTETRACYCLINE HYDROCHLORIDE VET IP","address":"501-502,AMBA SADAN,","city":"MUMBAI,MAHARASHTRA","supplier":"BRILLIANT PHARMACEUTICAL LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GENERAL IMPORT COMPANY (INDIA) PRIVATE LIMITED","customerCountry":"INDIA","quantity":"3000.00","actualQuantity":"3000","unit":"KGS","unitRateFc":"10.6","totalValueFC":"31889.9","currency":"USD","unitRateINR":"897","date":"07-Nov-2024","totalValueINR":"2691133.92","totalValueInUsd":"31889.9","indian_port":"JNPT","hs_no":"29413020","bill_no":"6551620","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"OFFICE,F,32\/F, PLAZA 88NO.88 YEUNG UK ROAD, TSUEN WAN,NT, HONG KONG SDNF CHINA","customerAddress":"501-502,AMBA SADAN,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731349800,"product":"TETRACYCLINE HYDROCHLORIDE (CAS: 64-75-5) TETRACYCLINE HYDROCHLORIDE (CAS: 64-75-5)","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"CBC (CHANGCHUN) PHARMACEUTICAL CO., LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"INDIA","quantity":"200.00","actualQuantity":"200","unit":"KGS","unitRateFc":"101.3","totalValueFC":"20454.9","currency":"USD","unitRateINR":"8630.8","date":"12-Nov-2024","totalValueINR":"1726152","totalValueInUsd":"20454.9","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29413090","bill_no":"6633412","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"ROOM 17163 , 17164 AND 17137 , 1 - (BUILDING), BLOCK B, WANDA PLAZA THE CROSS OF KAIXUAN ROAD AND TAIBE CN","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731436200,"product":"OXYTETRACYCLINE HYDROCHLORIDE IP (200 DRM)(LONGCHEM INTERNATIONAL TRADING COMPANY LIMITED) IUPAC NAME: (4S,4AR,5S,5AR,6SOXYTETRACYCLINE HYDROCHLORIDE IP (200 DRM)(LONGCHEM INTERNAT","address":"305 AGGARWAL CITY SQUARE","city":"DELHI","supplier":"LONGCHEM INTERNATIONALTRADING COMPANY LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SHAH TC DISTRIBUTION LLP","customerCountry":"INDIA","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"10.5","totalValueFC":"10601","currency":"USD","unitRateINR":"894.6","date":"13-Nov-2024","totalValueINR":"894600","totalValueInUsd":"10601","indian_port":"JNPT SEZ\/MUMBAI","hs_no":"29413020","bill_no":"6652421","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER, 61 MO DY ROAD, TSIM SHA TSUI, KOWLOON HON G KONG Kowloon, , HONG KONG HONG KONG","customerAddress":"305 AGGARWAL CITY SQUARE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731436200,"product":"OXYTETRACYCLINE HYDROCHLORIDE IP (200 DRM)(LONGCHEM INTERNATIONAL TRADING COMPANY LIMITED) IUPAC NAME: (4S,4AR,5S,5AR,6SOXYTETRACYCLINE HYDROCHLORIDE IP (200 DRM)(LONGCHEM INTERNAT","address":"305 AGGARWAL CITY SQUARE","city":"DELHI","supplier":"LONGCHEM INTERNATIONALTRADING COMPANY LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SHAH TC DISTRIBUTION LLP","customerCountry":"INDIA","quantity":"4000.00","actualQuantity":"4000","unit":"KGS","unitRateFc":"10.5","totalValueFC":"42404","currency":"USD","unitRateINR":"894.6","date":"13-Nov-2024","totalValueINR":"3578400","totalValueInUsd":"42404","indian_port":"JNPT SEZ\/MUMBAI","hs_no":"29413020","bill_no":"6655540","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"UNIT 2 OF LG 1, MIRROR TOWER, 61 MO DY ROAD, TSIM SHA TSUI, KOWLOON HON G KONG Kowloon, , HONG KONG HONG KONG","customerAddress":"305 AGGARWAL CITY SQUARE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732213800,"product":"TETRACYCLINE HYDROCHLORIDE IP","address":"PLOT NO 10-A, GIDC ESTATE,","city":"MAHESANA","supplier":"SINOBRIGHT PHARMACEUTICAL COMPANY LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"RISHABH LIFESCIENCE PRIVATE ","customerCountry":"INDIA","quantity":"2000.00","actualQuantity":"2000","unit":"KGS","unitRateFc":"20.8","totalValueFC":"42191.6","currency":"USD","unitRateINR":"1780.2","date":"22-Nov-2024","totalValueINR":"3560475.01","totalValueInUsd":"42191.6","indian_port":"JNPT","hs_no":"29413020","bill_no":"6812728","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"S LIMITED OFFICE F, 32\/F , PLAZA 88 NO.88 YEUNG UK ROAD, TSUEN WAN, NT, HONG KONG, CHINA","customerAddress":"PLOT NO 10-A, GIDC ESTATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732905000,"product":"TETRACYCLINE HYDROCHLORIDE","address":"L-4, PHASE-III,","city":"AKOLA. MAHARASHTRA","supplier":"ZHEJIANG UEASY BUSINESS ","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"LEBEN LABORATORIES PRIVATE ","customerCountry":"INDIA","quantity":"1500.00","actualQuantity":"1500","unit":"KGS","unitRateFc":"21","totalValueFC":"31859","currency":"USD","unitRateINR":"1792.4","date":"30-Nov-2024","totalValueINR":"2688525","totalValueInUsd":"31859","indian_port":"JNPT","hs_no":"29413020","bill_no":"6971143","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"LTD NO.22 GREAT WALL STREET XIACHEN G DISTRIC HANGZHOU CHINA CHINA","customerAddress":"L-4, PHASE-III,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732905000,"product":"TETRACYCLINE HYDROCHLORIDE BP\/USP (TETRACYCLINE HYDROCHLORIDE)","address":"25, 2ND PULIYUR MAIN ROAD,","city":"CHENNAI, TAMILNADU","supplier":"ZHEJIANG UEASY BUSINESS ","supplierCountry":"CHINA","foreign_port":"N\/A","customer":"MEDOPHARM PRIVATE LIMITED","customerCountry":"INDIA","quantity":"750.00","actualQuantity":"750","unit":"KGS","unitRateFc":"22","totalValueFC":"16688.1","currency":"USD","unitRateINR":"1877.7","date":"30-Nov-2024","totalValueINR":"1408275","totalValueInUsd":"16688.1","indian_port":"Madras Sea","hs_no":"29413020","bill_no":"6972204","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"NO 22 GREAT WALL STREET XIACHENG DI STRICT HANGZHOU China","customerAddress":"25, 2ND PULIYUR MAIN ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1733077800,"product":"TETRACYCLINE HYDROCHLORIDE (CAS: 64-75-5)","address":"882\/1-871, NEAR KANKAVATI ,VILLAGE-","city":"AHMEDABAD, GUJARAT","supplier":"N\/A","supplierCountry":"CHINA","foreign_port":"XIAMAN","customer":"AMNEAL PHARMACEUTICALS","customerCountry":"INDIA","quantity":"125.00","actualQuantity":"125","unit":"KGS","unitRateFc":"50","totalValueFC":"6278","currency":"USD","unitRateINR":"4267.5","date":"02-Dec-2024","totalValueINR":"533438","totalValueInUsd":"6278","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29413020","bill_no":"6998038","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"XIAMAN","supplierAddress":"N\/A","customerAddress":"882\/1-871, NEAR KANKAVATI ,VILLAGE-"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1733682600,"product":"TETRACYCLINE HYDROCHLORIDE IP TETRACYCLINE HYDROCHLORIDE IP","address":"48, CHANDRA GUPTA ESTATE,","city":"MUMBAI, MAHARASHTRA.","supplier":"BRILLIANT PHARMACEUTICAL LIMITED.","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GORANG INTERNATIONAL","customerCountry":"INDIA","quantity":"3000.00","actualQuantity":"3000","unit":"KGS","unitRateFc":"20.6","totalValueFC":"62357.4","currency":"USD","unitRateINR":"1766.1","date":"09-Dec-2024","totalValueINR":"5298443.9","totalValueInUsd":"62357.4","indian_port":"JNPT","hs_no":"29413020","bill_no":"7126390","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"OFFICE F, 32\/F, PLAZA 88 NO.88 YEUN G UK ROAD, TSUEN WAN NT, HONG KONG CHINA ., ., China China","customerAddress":"48, CHANDRA GUPTA ESTATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734546600,"product":"OXYTETRACYCLINE HYDROCHLORIDE IP. OXYTETRACYCLINE HYDROCHLORIDE IP.","address":"48, CHANDRA GUPTA ESTATE,","city":"MUMBAI, MAHARASHTRA.","supplier":"HEBEI HONGCHENG YAXIN TECHNOLOGY CO LTD","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"GORANG INTERNATIONAL","customerCountry":"INDIA","quantity":"10000.00","actualQuantity":"10000","unit":"KGS","unitRateFc":"12.3","totalValueFC":"124187.4","currency":"USD","unitRateINR":"1055.2","date":"19-Dec-2024","totalValueINR":"10552080","totalValueInUsd":"124187.4","indian_port":"JNPT","hs_no":"29413020","bill_no":"7327521","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"NO. 50 SHENGXUE ROAD LUANCHENG SHIJ IAZHUANG HEBEI PROVINCE CHINA CHIN A, , China China","customerAddress":"48, CHANDRA GUPTA ESTATE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1734892200,"product":"OXYTETRACYCLINE HYDROCHLORIDE VET IP OXYTETRACYCLINE HYDROCHLORIDE IP","address":"13,VITHALDAS ROAD,BULAKHIDAS","city":"MUMBAI,MAHARASHTRA","supplier":"BRILLIANT PHARMACEUTICAL LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"MEDI PHARMA DRUG ","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"10.6","totalValueFC":"53460.2","currency":"USD","unitRateINR":"908.5","date":"23-Dec-2024","totalValueINR":"4542457.5","totalValueInUsd":"53460.2","indian_port":"JNPT","hs_no":"29413020","bill_no":"7405940","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"6\/F MANULIFE PLACE 348 KWUN TONG RO AD KOWLOON HONG KONG SDNF CHINA","customerAddress":"13,VITHALDAS ROAD,BULAKHIDAS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1735237800,"product":"OXYTETRACYCLINE HYDROCHLORIDE VET IP OXYTETRACYCLINE HYDROCHLORIDE VET IP","address":"AGARWAL B2B CENTRE, 604 KANCHPADA","city":"MUMBAI","supplier":"BRILLIANT PHARMACEUTICAL LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI","customer":"SUN RISE ENTERPRISES","customerCountry":"INDIA","quantity":"5000.00","actualQuantity":"5000","unit":"KGS","unitRateFc":"10.6","totalValueFC":"53438.2","currency":"USD","unitRateINR":"908.1","date":"27-Dec-2024","totalValueINR":"4540587.5","totalValueInUsd":"53438.2","indian_port":"JNPT","hs_no":"29413020","bill_no":"7484013","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI","supplierAddress":"OFFICE F,32\/F, PLAZA 88 NO.88 YEUNG UK ROAD, TSUEN WAN, NT, HONG KONG, CN","customerAddress":"AGARWAL B2B CENTRE, 604 KANCHPADA"}]
    04-Jan-2021
    27-Dec-2024
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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - CAPSULE;ORAL - 250MG

    USFDA APPLICATION NUMBER - 50278

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    DOSAGE - CAPSULE;ORAL - 500MG

    USFDA APPLICATION NUMBER - 50278

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    USP

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    ABOUT THIS PAGE

    Actisite Manufacturers

    A Actisite manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Actisite, including repackagers and relabelers. The FDA regulates Actisite manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Actisite API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Actisite manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Actisite Suppliers

    A Actisite supplier is an individual or a company that provides Actisite active pharmaceutical ingredient (API) or Actisite finished formulations upon request. The Actisite suppliers may include Actisite API manufacturers, exporters, distributors and traders.

    click here to find a list of Actisite suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Actisite USDMF

    A Actisite DMF (Drug Master File) is a document detailing the whole manufacturing process of Actisite active pharmaceutical ingredient (API) in detail. Different forms of Actisite DMFs exist exist since differing nations have different regulations, such as Actisite USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Actisite DMF submitted to regulatory agencies in the US is known as a USDMF. Actisite USDMF includes data on Actisite's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Actisite USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Actisite suppliers with USDMF on PharmaCompass.

    Actisite JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Actisite Drug Master File in Japan (Actisite JDMF) empowers Actisite API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Actisite JDMF during the approval evaluation for pharmaceutical products. At the time of Actisite JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Actisite suppliers with JDMF on PharmaCompass.

    Actisite CEP

    A Actisite CEP of the European Pharmacopoeia monograph is often referred to as a Actisite Certificate of Suitability (COS). The purpose of a Actisite CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Actisite EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Actisite to their clients by showing that a Actisite CEP has been issued for it. The manufacturer submits a Actisite CEP (COS) as part of the market authorization procedure, and it takes on the role of a Actisite CEP holder for the record. Additionally, the data presented in the Actisite CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Actisite DMF.

    A Actisite CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Actisite CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Actisite suppliers with CEP (COS) on PharmaCompass.

    Actisite NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Actisite as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Actisite API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Actisite as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Actisite and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Actisite NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Actisite suppliers with NDC on PharmaCompass.

    Actisite GMP

    Actisite Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Actisite GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Actisite GMP manufacturer or Actisite GMP API supplier for your needs.

    Actisite CoA

    A Actisite CoA (Certificate of Analysis) is a formal document that attests to Actisite's compliance with Actisite specifications and serves as a tool for batch-level quality control.

    Actisite CoA mostly includes findings from lab analyses of a specific batch. For each Actisite CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Actisite may be tested according to a variety of international standards, such as European Pharmacopoeia (Actisite EP), Actisite JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Actisite USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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