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1. 2-allyl-1-(6-(2-hydroxy-2-propanyl)-2-pyridinyl)-6-((4-(4-methyl-1-piperazinyl)phenyl)amino)-1,2-dihydro-3h-pyrazolo(3,4-d)pyrimidin-3-one
2. 3h-pyrazolo(3,4-d)pyrimidin-3-one, 1,2-dihydro-1-(6-(1-hydroxy-1-methylethyl)-2-pyridinyl)-6-((4-(4-methyl-1-piperazinyl)phenyl)amino)-2-(2-propen-1-yl)-
3. Azd 1775
4. Azd-1775
5. Azd1775
6. Mk 1775
7. Mk-1775
8. Mk1775
1. Mk-1775
2. 955365-80-7
3. Mk1775
4. Mk 1775
5. Azd1775
6. Azd-1775
7. Azd 1775
8. 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one
9. 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1h-pyrazolo[3,4-d]pyrimidin-3(2h)-one
10. 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1h-pyrazolo[3,4-d]pyrimidin-3(2h)-one
11. K2t6hjx3i3
12. Mfcd17215200
13. Adavosertib (usan)
14. 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)pyrazolo[3,4-d]pyrimidin-3-one
15. Adavosertib [usan]
16. 3h-pyrazolo(3,4-d)pyrimidin-3-one, 1,2-dihydro-1-(6-(1-hydroxy-1-methylethyl)-2-pyridinyl)-6-((4-(4-methyl-1-piperazinyl)phenyl)amino)-2-(2-propen-1-yl)-
17. 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-{[4-(4-methylpiperazin-1-yl)phenyl]amino}-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one
18. 3h-pyrazolo[3,4-d]pyrimidin-3-one, 1,2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)-
19. Unii-k2t6hjx3i3
20. 8x7
21. Kinome_2656
22. Adavosertib [inn]
23. Adavosertib (mk-1775)
24. Adavosertib [who-dd]
25. Mls006011025
26. Gtpl7702
27. Schembl1504444
28. Chembl1976040
29. Chebi:91414
30. Dtxsid30241868
31. Ex-a331
32. Hms3295k03
33. Hms3654h20
34. Hms3744i13
35. Bcp01928
36. Bdbm50240826
37. Mk-1775 (wee-1)
38. Nsc754352
39. Nsc800793
40. S1525
41. Zinc63539231
42. Akos024259153
43. Mk-1775(azd-1775,adavosertib)
44. Adavosertib Pound Mk-1775 Pound(c)
45. Am90274
46. Bcp9000937
47. Ccg-264905
48. Cs-0105
49. Db11740
50. Nsc-754352
51. Nsc-800793
52. Sb16663
53. Ncgc00263183-01
54. Ncgc00263183-09
55. Ncgc00263183-10
56. 2-allyl-1-(6-(2-hydroxy-2-propanyl)-2-pyridinyl)-6-((4-(4-methyl-1-piperazinyl)phenyl)amino)-1,2-dihydro-3h-pyrazolo(3,4-d)pyrimidin-3-one
57. 2-allyl-1-[6-(2-hydroxy-2-propyl)-2-pyridyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrazolo[3,4-d]pyrimidin-3(2h)-one
58. Ac-28416
59. As-17001
60. Bm161385
61. Hy-10993
62. Smr004702820
63. Sy258875
64. Ft-0699265
65. Sw218122-2
66. D11361
67. Brd-k54256913-001-01-2
68. Q27074716
69. 1,2-dihydro-1-(6-(1-hydroxy-1-methylethyl)-2-pyridinyl)-6-((4-(4-methyl-1-piperazinyl)phenyl)amino)-2-(2-propen-1-yl)-3h-pyrazolo(3,4-d)pyrimidin-3-one
70. 1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)anilino)-2-(prop-2-en-1-yl)-1,2-dihydro-3h-pyrazolo(3,4-d)pyrimidin-3-one
71. 1075739-30-8
72. 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1h-pyrazo
73. 2-allyl-1-[6-(1-hydroxy-1-methyl-ethyl)-pyridin-2-yl]-6-[4-(4-methyl-piperazin-1-yl)-phenylamino]-1,2-dihydro-pyrazolo[3,4-d]pyrimidin-3-one
74. 2-allyl-1-[6-(1-hydroxy-1-methylethyl)pyridin-2-yl]-6-[[4-(4-methylpiperazin-1-yl)phenyl]amino]-1,2-dihydro-3h-pyrazolo[3,4-d]pyrimidin-3-one
Molecular Weight | 500.6 g/mol |
---|---|
Molecular Formula | C27H32N8O2 |
XLogP3 | 3.1 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 9 |
Rotatable Bond Count | 7 |
Exact Mass | 500.26482229 g/mol |
Monoisotopic Mass | 500.26482229 g/mol |
Topological Polar Surface Area | 101 Ų |
Heavy Atom Count | 37 |
Formal Charge | 0 |
Complexity | 795 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Enzyme Inhibitors
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)
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PharmaCompass offers a list of Adavosertib API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Adavosertib manufacturer or Adavosertib supplier for your needs.
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A Adavosertib manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Adavosertib, including repackagers and relabelers. The FDA regulates Adavosertib manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Adavosertib API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Adavosertib supplier is an individual or a company that provides Adavosertib active pharmaceutical ingredient (API) or Adavosertib finished formulations upon request. The Adavosertib suppliers may include Adavosertib API manufacturers, exporters, distributors and traders.
Adavosertib Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Adavosertib GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Adavosertib GMP manufacturer or Adavosertib GMP API supplier for your needs.
A Adavosertib CoA (Certificate of Analysis) is a formal document that attests to Adavosertib's compliance with Adavosertib specifications and serves as a tool for batch-level quality control.
Adavosertib CoA mostly includes findings from lab analyses of a specific batch. For each Adavosertib CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Adavosertib may be tested according to a variety of international standards, such as European Pharmacopoeia (Adavosertib EP), Adavosertib JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Adavosertib USP).