Synopsis
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1. 56287-74-2
2. Arofuto
3. 4(3h)-quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
4. Airomate
5. Hq-495
6. Co4u2c8orz
7. 6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4(3h)-one
8. 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one
9. 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3h)-quinazolinone
10. 6-amino-2-(fluoromethyl)-3-o-tolyl-4(3h)-quinazolinone
11. Afloqualon
12. 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
13. 6-amino-2-(fluoromethyl)-3-o-tolylquinazolin-4(3h)-one
14. Afloqualona
15. Afloqualonum
16. Afloqualone [inn:jan]
17. Afloqualonum [inn-latin]
18. Afloqualona [inn-spanish]
19. Unii-co4u2c8orz
20. Hq 495
21. Brn 0819769
22. Airomate (tn)
23. 6-amino-2-(fluoromethyl)-3-o-tolyl-4(3h)-chinazolinon
24. Afloqualone [mi]
25. 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4(3h)-one
26. Afloqualone [inn]
27. Afloqualone [jan]
28. 6-amino-3,4-dihydro-2-fluoromethyl-3-(2-methylphenyl)-4-chinazolinon
29. Dsstox_cid_2562
30. Afloqualone (jp17/inn)
31. Afloqualone [mart.]
32. Dsstox_rid_76631
33. Dsstox_gsid_22562
34. Afloqualone [who-dd]
35. Mls006010086
36. Schembl400184
37. Chembl2105918
38. Dtxsid5022562
39. Chebi:31177
40. 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-4-quinazolinone
41. Hms3885g19
42. Bcp13264
43. Hy-b1833
44. Tox21_112447
45. Mfcd00867693
46. S3663
47. Zinc13831145
48. Akos015842375
49. Ac-1608
50. Ccg-267278
51. Cs-5009
52. Ncgc00167443-02
53. As-11726
54. Smr004701231
55. Cas-56287-74-2
56. Ft-0653844
57. D01638
58. D95096
59. A830986
60. Q4689289
61. 2-fluoromethyl-3-(o-tolyl)-6-amino-4(3h)-quinazolinone
62. 6-azanyl-2-(fluoranylmethyl)-3-(2-methylphenyl)quinazolin-4-one
Molecular Weight | 283.30 g/mol |
---|---|
Molecular Formula | C16H14FN3O |
XLogP3 | 2.2 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 2 |
Exact Mass | 283.11209024 g/mol |
Monoisotopic Mass | 283.11209024 g/mol |
Topological Polar Surface Area | 58.7 Ų |
Heavy Atom Count | 21 |
Formal Charge | 0 |
Complexity | 439 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
Muscle Relaxants, Central
A heterogeneous group of drugs used to produce muscle relaxation, excepting the neuromuscular blocking agents. They have their primary clinical and therapeutic uses in the treatment of muscle spasm and immobility associated with strains, sprains, and injuries of the back and, to a lesser degree, injuries to the neck. They have been used also for the treatment of a variety of clinical conditions that have in common only the presence of skeletal muscle hyperactivity, for example, the muscle spasms that can occur in MULTIPLE SCLEROSIS. (From Smith and Reynard, Textbook of Pharmacology, 1991, p358) (See all compounds classified as Muscle Relaxants, Central.)
Photosensitizing Agents
Drugs that are pharmacologically inactive but when exposed to ultraviolet radiation or sunlight are converted to their active metabolite to produce a beneficial reaction affecting the diseased tissue. These compounds can be administered topically or systemically and have been used therapeutically to treat psoriasis and various types of neoplasms. (See all compounds classified as Photosensitizing Agents.)
Afloqualone has known human metabolites that include Afloqualone N-glucuronide.
S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560
ABOUT THIS PAGE
A Afloqualone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Afloqualone, including repackagers and relabelers. The FDA regulates Afloqualone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Afloqualone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Afloqualone manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Afloqualone supplier is an individual or a company that provides Afloqualone active pharmaceutical ingredient (API) or Afloqualone finished formulations upon request. The Afloqualone suppliers may include Afloqualone API manufacturers, exporters, distributors and traders.
click here to find a list of Afloqualone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.
Pharmaceutical companies submit a Afloqualone Drug Master File in Korea (Afloqualone KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Afloqualone. The MFDS reviews the Afloqualone KDMF as part of the drug registration process and uses the information provided in the Afloqualone KDMF to evaluate the safety and efficacy of the drug.
After submitting a Afloqualone KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Afloqualone API can apply through the Korea Drug Master File (KDMF).
click here to find a list of Afloqualone suppliers with KDMF on PharmaCompass.
Afloqualone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Afloqualone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Afloqualone GMP manufacturer or Afloqualone GMP API supplier for your needs.
A Afloqualone CoA (Certificate of Analysis) is a formal document that attests to Afloqualone's compliance with Afloqualone specifications and serves as a tool for batch-level quality control.
Afloqualone CoA mostly includes findings from lab analyses of a specific batch. For each Afloqualone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Afloqualone may be tested according to a variety of international standards, such as European Pharmacopoeia (Afloqualone EP), Afloqualone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Afloqualone USP).
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