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Chemistry

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Also known as: 187949-02-6, Ur-9825, W-0027, Ydw24y8iab, 7-chloro-3-((1r,2r)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl)quinazolin-4(3h)-one, W0027
Molecular Formula
C20H16ClF2N5O2
Molecular Weight
431.8  g/mol
InChI Key
UHIXWHUVLCAJQL-MPBGBICISA-N
FDA UNII
YDW24Y8IAB

Albaconazole
Albaconazole has been used in trials studying the basic science of Onychomycosis.
1 2D Structure

Albaconazole

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-chloro-3-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]quinazolin-4-one
2.1.2 InChI
InChI=1S/C20H16ClF2N5O2/c1-12(28-11-25-18-6-13(21)2-4-15(18)19(28)29)20(30,8-27-10-24-9-26-27)16-5-3-14(22)7-17(16)23/h2-7,9-12,30H,8H2,1H3/t12-,20-/m1/s1
2.1.3 InChI Key
UHIXWHUVLCAJQL-MPBGBICISA-N
2.1.4 Canonical SMILES
CC(C(CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3C=NC4=C(C3=O)C=CC(=C4)Cl
2.1.5 Isomeric SMILES
C[C@H]([C@](CN1C=NC=N1)(C2=C(C=C(C=C2)F)F)O)N3C=NC4=C(C3=O)C=CC(=C4)Cl
2.2 Other Identifiers
2.2.1 UNII
YDW24Y8IAB
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 7-chloro-3-(2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl)quinazolin-4(3h)-one

2. Ur 9825

3. Ur-9825

2.3.2 Depositor-Supplied Synonyms

1. 187949-02-6

2. Ur-9825

3. W-0027

4. Ydw24y8iab

5. 7-chloro-3-((1r,2r)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl)quinazolin-4(3h)-one

6. W0027

7. 4(3h)-quinazolinone, 7-chloro-3-((1r,2r)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl)-

8. 7-chloro-3-((2r,3r)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1h-1,2,4-triazol-1-yl)butan-2-yl)quinazolin-4(3h)-one

9. Albaconazol

10. Albaconazole [inn]

11. Ur 9825

12. Unii-ydw24y8iab

13. Albaconazole [usan:inn]

14. Albaconazol [inn-spanish]

15. 7-chloro-3-[(2r,3r)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]quinazolin-4-one

16. Albaconazole (usan/inn)

17. Albaconazole [usan]

18. Chembl298817

19. Schembl1262830

20. Dtxsid3058244

21. Zinc602086

22. Bdbm50011477

23. Mfcd09837823

24. Ur9825

25. Akos027327579

26. Db12073

27. 4(3h)-quinazolinone,7-chloro-3-[(1r,2r)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl]-

28. 7-chloro-3-(2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl)quinazolin-4(3h)-one

29. 7-chloro-3-[(1r,2r)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1,2,4-triazol-1-yl)propyl]quinazolin-4-one

30. D09702

31. W 0027

32. J-012103

33. Q4708967

34. (1r,2r)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2, 4-triazol-1-yl)propyl]quinazolin-4(3h)-one

35. (1r,2r)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1h-1,2,4-triazol-1-yl)propyl]quinazolin-4(3h)-one

36. 206350-10-9

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 431.8 g/mol
Molecular Formula C20H16ClF2N5O2
XLogP32.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass431.0960588 g/mol
Monoisotopic Mass431.0960588 g/mol
Topological Polar Surface Area83.6 Ų
Heavy Atom Count30
Formal Charge0
Complexity673
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antifungal Agents

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)


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ABOUT THIS PAGE

Albaconazole Manufacturers

A Albaconazole manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Albaconazole, including repackagers and relabelers. The FDA regulates Albaconazole manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Albaconazole API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Albaconazole Suppliers

A Albaconazole supplier is an individual or a company that provides Albaconazole active pharmaceutical ingredient (API) or Albaconazole finished formulations upon request. The Albaconazole suppliers may include Albaconazole API manufacturers, exporters, distributors and traders.

click here to find a list of Albaconazole suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Albaconazole USDMF

A Albaconazole DMF (Drug Master File) is a document detailing the whole manufacturing process of Albaconazole active pharmaceutical ingredient (API) in detail. Different forms of Albaconazole DMFs exist exist since differing nations have different regulations, such as Albaconazole USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Albaconazole DMF submitted to regulatory agencies in the US is known as a USDMF. Albaconazole USDMF includes data on Albaconazole's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Albaconazole USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Albaconazole suppliers with USDMF on PharmaCompass.

Albaconazole GMP

Albaconazole Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Albaconazole GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Albaconazole GMP manufacturer or Albaconazole GMP API supplier for your needs.

Albaconazole CoA

A Albaconazole CoA (Certificate of Analysis) is a formal document that attests to Albaconazole's compliance with Albaconazole specifications and serves as a tool for batch-level quality control.

Albaconazole CoA mostly includes findings from lab analyses of a specific batch. For each Albaconazole CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Albaconazole may be tested according to a variety of international standards, such as European Pharmacopoeia (Albaconazole EP), Albaconazole JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Albaconazole USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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