EUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF, $ API Reference Price

1 API Suppliers
1 USDMF
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

99 FDF Dossiers, 76 Europe, 18 South Africa, 5 Listed Dossiers

99 FDF Dossiers
76 Europe
18 South Africa
5 Listed Dossiers

DIGITAL CONTENT

2 NEWS #PharmaBuzz

media
2 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

76 Finished Drug Prices, 3 Annual Reports

globalSalesInformation
76 Finished Drug Prices
3 Annual Reports

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 101

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

486

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 78tja4e8i9, 138624-11-0, Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-, monohydrate, Phosphonic acid, p,p'-(4-amino-1-hydroxybutylidene)bis-, hydrate (1:1), Unii-78tja4e8i9, Schembl167772

Molecular Formula

C₄H₁₅NO₈P₂

Molecular Weight

267.11 g/mol

InChI Key

AQAZLLYAEFBJMU-UHFFFAOYSA-N

FDA UNII

78TJA4E8I9

1 2D Structure

Alendronic Acid Monohydrate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid;hydrate

2.1.2 InChI

InChI=1S/C4H13NO7P2.H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);1H2

2.1.3 InChI Key

AQAZLLYAEFBJMU-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN.O

2.2 Other Identifiers

2.2.1 UNII

78TJA4E8I9

2.3 Synonyms

2.3.1 Depositor-Supplied Synonyms

1. 78tja4e8i9

2. 138624-11-0

3. Phosphonic Acid, (4-amino-1-hydroxybutylidene)bis-, Monohydrate

4. Phosphonic Acid, P,p'-(4-amino-1-hydroxybutylidene)bis-, Hydrate (1:1)

5. Unii-78tja4e8i9

6. Schembl167772

7. Dtxsid00160734

8. Q27266693

2.4 Create Date

2007-02-12

3 Chemical and Physical Properties

Molecular Formula	C₄H₁₅NO₈P₂
Molecular Weight	267.11 g/mol
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	5
Exact Mass	267.02729043 g/mol
Monoisotopic Mass	267.02729043 g/mol
Topological Polar Surface Area	162 Å²
Heavy Atom Count	15
Formal Charge	0
Complexity	257
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

[{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1627929000,"product":"ALENDRONIC ACID (GROUP-A) (INVOICE.NO:52 21500098 DT:02.08.2021","address":"7.1.77\/E\/1\/303, DHARAM KARAM ROADAMEERPET","city":"HYDERABAD,A.P.","supplier":"DIVIS LABORATORIES","supplierCountry":"INDIA","foreign_port":"DUBLIN","customer":"MERCK & CO","customerCountry":"IRELAND","quantity":"4030.00","actualQuantity":"4030","unit":"KGS","unitRateFc":"103.3","totalValueFC":"404464.5","currency":"USD","unitRateINR":7443.6999999999998,"date":"03-Aug-2021","totalValueINR":"29998111","totalValueInUsd":"404464.5","indian_port":"HYDERABAD AIR","hs_no":"29313900","bill_no":"3581762","productDescription":"API","marketType":"REGULATED MARKET","country":"IRELAND","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"7.1.77\/E\/1\/303, DHARAM KARAM ROADAMEERPET, HYDERABAD,A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1628706600,"product":"ALENDRONIC ACID (GROUP-A) (INVOICE.NO:52 21500109 DT:12.08.2021)","address":"7.1.77\/E\/1\/303, DHARAM KARAM ROADAMEERPET","city":"HYDERABAD,A.P.","supplier":"DIVIS LABORATORIES","supplierCountry":"INDIA","foreign_port":"DUBLIN","customer":"MERCK & CO","customerCountry":"IRELAND","quantity":"2170.00","actualQuantity":"2170","unit":"KGS","unitRateFc":"102.9","totalValueFC":"216902.1","currency":"USD","unitRateINR":7413.3999999999996,"date":"12-Aug-2021","totalValueINR":"16087078","totalValueInUsd":"216902.1","indian_port":"HYDERABAD AIR","hs_no":"29313900","bill_no":"3813805","productDescription":"API","marketType":"REGULATED MARKET","country":"IRELAND","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"7.1.77\/E\/1\/303, DHARAM KARAM ROADAMEERPET, HYDERABAD,A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1654021800,"product":"ALENDRONIC ACID ITEM NO. 40 A2120","address":"NO.189,MN PARK,SYNERGY SQUARE 1,,G ENOME VALLEY,TURKAPALLY VILLAGE,","city":"SHAMEERPET MANDAL MEDCHAL MALKAJGIR","supplier":"TOKYO CHEMICAL INDUSTRY","supplierCountry":"INDIA","foreign_port":"TOKYO","customer":"TOKYO CHEMICAL INDUSTRY","customerCountry":"JAPAN","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"58.5","totalValueFC":"179.5","currency":"USD","unitRateINR":4666.666666666667,"date":"01-Jun-2022","totalValueINR":"14000","totalValueInUsd":"179.5","indian_port":"MADRAS AIR","hs_no":"29349990","bill_no":"1826058","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRAS AIR","supplierAddress":"NO.189,MN PARK,SYNERGY SQUARE 1,,G ENOME VALLEY,TURKAPALLY VILLAGE,, SHAMEERPET MANDAL MEDCHAL MALKAJGIR","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1670437800,"product":"ALENDRONIC ACID (INVOICE NO: 5221500570,","address":"DIVI TOWERS, 1-72\/23 P\/DIVIS\/303 CYBER HILLS, GACHIBOWLI CONTACT NO","city":"HYDERABAD TELANGANA INDIA","supplier":"DIVIS LABORATORIES","supplierCountry":"INDIA","foreign_port":"DUBLIN","customer":"TO THE ORDER OF","customerCountry":"IRELAND","quantity":"4960.00","actualQuantity":"4960","unit":"KGS","unitRateFc":"103","totalValueFC":"497826.2","currency":"USD","unitRateINR":8270.967741935483,"date":"08-Dec-2022","totalValueINR":"41024000","totalValueInUsd":"497826.2","indian_port":"VIZAG SEA","hs_no":"29314400","bill_no":"6024130","productDescription":"API","marketType":"REGULATED MARKET","country":"IRELAND","selfForZScoreResived":"Pharma Grade","supplierPort":"VIZAG SEA","supplierAddress":"DIVI TOWERS, 1-72\/23 P\/DIVIS\/303 CYBER HILLS, GACHIBOWLI CONTACT NO, HYDERABAD TELANGANA INDIA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1688495400,"product":"ALENDRONIC ACID","address":"DIVI TOWERS, 1-72\/23 P\/DIVIS\/303 CYBER HILLS, GACHIBOWLI Contact No","city":"HYDERABAD TELANGANA INDIA","supplier":"DIVIS LABORATORIES","supplierCountry":"INDIA","foreign_port":"DUBLIN","customer":"TO THE ORDER OF","customerCountry":"IRELAND","quantity":"4960.00","actualQuantity":"4960","unit":"KGS","unitRateFc":"103","totalValueFC":"505660.5","currency":"USD","unitRateINR":8379.0323004032252,"date":"05-Jul-2023","totalValueINR":"41560000.21","totalValueInUsd":"505660.5","indian_port":"VIZAG SEA","hs_no":"29314400","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"IRELAND","selfForZScoreResived":"Pharma Grade","supplierPort":"VIZAG SEA","supplierAddress":"DIVI TOWERS, 1-72\/23 P\/DIVIS\/303 CYBER HILLS, GACHIBOWLI Contact No, HYDERABAD TELANGANA INDIA","customerAddress":""}]