All Manufacturers, Suppliers, Distributors and Exporters of Alimemazine with approved Health Canada of Finished Dosage Form listed on PharmaCompass.com

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ACTIVE PHARMA INGREDIENTS

8 API Suppliers, 3 USDMF, 1 CEP/COS, 1 JDMF, 8 NDC API, 2 VMF, 6 Listed Suppliers, $ API Reference Price

8 API Suppliers
3 USDMF
1 CEP/COS
1 JDMF
8 NDC API
2 VMF
6 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

1 Drugs in Development

1 Drugs in Development

FINISHED DOSAGE FORMULATIONS

14 FDF Dossiers, 5 FDA Orange Book, 5 Europe, 3 Canada, 1 South Africa

14 FDF Dossiers
5 FDA Orange Book
5 Europe
3 Canada
1 South Africa

GLOBAL SALES INFORMATION

3 Finished Drug Prices

globalSalesInformation
3 Finished Drug Prices

MARKET PLACE

3 APIs

marketPlace
3 APIs

REF. STANDARDS & IMPURITIES

1 USP , 3 Others

otherSolutions
1 USP
3 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Trimeprazine tartrate, 4330-99-8, Trimeprazine hemitartrate salt, Nsc-17475, Nsc-757358, Prestwick_144

Molecular Formula

C₄₀H₅₀N₄O₆S₂

Molecular Weight

747.0 g/mol

InChI Key

AJZJIYUOOJLBAU-UHFFFAOYSA-N

1 2D Structure

Alimemazine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2,3-dihydroxybutanedioic acid;N,N,2-trimethyl-3-phenothiazin-10-ylpropan-1-amine

2.1.2 InChI

InChI=1S/2C18H22N2S.C4H6O6/c2*1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20;5-1(3(7)8)2(6)4(9)10/h2*4-11,14H,12-13H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)

2.1.3 InChI Key

AJZJIYUOOJLBAU-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)CN(C)C.CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)CN(C)C.C(C(C(=O)O)O)(C(=O)O)O

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Temaril

2. Theralen

3. Theraline

4. Trimeprazine Tartrate

2.2.2 Depositor-Supplied Synonyms

1. Trimeprazine Tartrate

2. 4330-99-8

3. Trimeprazine Hemitartrate Salt

4. Nsc-17475

5. Nsc-757358

6. Prestwick_144

7. Chembl3989885

8. Hms1570j05

9. Hms3714j05

10. Trimeprazine Hemi-(+)-tartrate Salt

11. Ccg-220842

2.3 Create Date

2006-04-14

3 Chemical and Physical Properties

Molecular Formula	C₄₀H₅₀N₄O₆S₂
Molecular Weight	747.0 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	11
Exact Mass	746.31717767 g/mol
Monoisotopic Mass	746.31717767 g/mol
Topological Polar Surface Area	179 Å²
Heavy Atom Count	52
Formal Charge	0
Complexity	445
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	4
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	3

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Histamine H1 Antagonists

Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. (See all compounds classified as Histamine H1 Antagonists.)

API SUPPLIERS

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USDMF

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CEP/COS

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JDMF

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NDC API

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VMF

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Listed Suppliers

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API Reference Price

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