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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

21 API Suppliers, 4 USDMF, 7 NDC API, 17 Listed Suppliers, $ API Reference Price

21 API Suppliers
4 USDMF
7 NDC API
17 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

97 Drugs in Development

97 Drugs in Development

INTERMEDIATES

16 Intermediates Suppliers

16 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

145 FDF Dossiers, 10 FDA Orange Book, 46 Europe, 10 Canada, 20 Australia, 17 South Africa, 42 Listed Dossiers

145 FDF Dossiers
10 FDA Orange Book
46 Europe
10 Canada
20 Australia
17 South Africa
42 Listed Dossiers

DIGITAL CONTENT

6 DATA COMPILATION #PharmaFlow, 114 NEWS #PharmaBuzz

media
6 DATA COMPILATION #PharmaFlow
114 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 40 Finished Drug Prices, 10 Annual Reports

globalSalesInformation
1 US Medicaid Prescriptions
40 Finished Drug Prices
10 Annual Reports

MARKET PLACE

6 APIs, 14 FDF Dossiers, 1 Intermediates

marketPlace
6 APIs
14 FDF Dossiers
1 Intermediates

PATENTS & EXCLUSIVITIES

2 US Patents, 8 Health Canada Patents

patents
2 US Patents
8 Health Canada Patents

REF. STANDARDS & IMPURITIES

1 USP , 5 Others

otherSolutions
1 USP
5 Others

Rochem Pemetrexed popup

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

145

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

114

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

7,434,149

Annual Reports (USD Million)

16,927

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Click the button for full data set

Also known as:

Molecular Formula

C₂₀H₂₁N₅O₆

Molecular Weight

427.4 g/mol

InChI Key

WBXPDJSOTKVWSJ-CYBMUJFWSA-N

1 2D Structure

Pemetrexed

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioic acid

2.1.2 InChI

InChI=1S/C20H21N5O6/c21-20-24-16-15(18(29)25-20)12(9-22-16)6-3-10-1-4-11(5-2-10)17(28)23-13(19(30)31)7-8-14(26)27/h1-2,4-5,9,13H,3,6-8H2,(H,23,28)(H,26,27)(H,30,31)(H4,21,22,24,25,29)/t13-/m1/s1

2.1.3 InChI Key

WBXPDJSOTKVWSJ-CYBMUJFWSA-N

2.1.4 Canonical SMILES

C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)NC(CCC(=O)O)C(=O)O

2.1.5 Isomeric SMILES

C1=CC(=CC=C1CCC2=CNC3=C2C(=O)N=C(N3)N)C(=O)N[C@H](CCC(=O)O)C(=O)O

2.2 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₂₁N₅O₆
Molecular Weight	427.4 g/mol
XLogP3	0.2
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Exact Mass	427.14918341 g/mol
Monoisotopic Mass	427.14918341 g/mol
Topological Polar Surface Area	187 A^2
Heavy Atom Count	31
Formal Charge	0
Complexity	748
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Information

1 of 2
Drug Name	Alimta
PubMed Health	Pemetrexed (Injection)
Drug Classes	Antineoplastic Agent
Drug Label	Pemetrexed disodium heptahydrate has the chemical name L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. It is a white to almost-white solid with a molecular formula of C...
Active Ingredient	Pemetrexed; Pemetrexed disodium
Dosage Form	Injectable
Route	injection; Iv (infusion)
Strength	eq 500mg base/vial; 500mg; eq 100mg base/vial
Market Status	Prescription
Company	Lilly

2 of 2
Drug Name	Alimta
PubMed Health	Pemetrexed (Injection)
Drug Classes	Antineoplastic Agent
Drug Label	Pemetrexed disodium heptahydrate has the chemical name L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. It is a white to almost-white solid with a molecular formula of C...
Active Ingredient	Pemetrexed; Pemetrexed disodium
Dosage Form	Injectable
Route	injection; Iv (infusion)
Strength	eq 500mg base/vial; 500mg; eq 100mg base/vial
Market Status	Prescription
Company	Lilly

API SUPPLIERS

01

Rochem International Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3F18

Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

02

Shandong Boyuan Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3A142 & #3B136

Shandong Boyuan is a Chinese manufacturer of GMP & CEP APIs & pharmaceutical intermediates.

Contact Supplier

China

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

03

ChemWerth Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #1D3

ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

04

Gonane Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Attending

Gonane has API manufacturing expertise in new-age Corticosteroids, Hormones and other pharma raw materials.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT

05

HRV Global Life Sciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

CPhI Worldwide, Milan

Booth #3A25

HRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

Contact Supplier

India

Virtual Booth

Digital Content

USDMF CEP/COS JDMF EU-WC NDC KDMF VMF AU, ASMF

AUDIT

06

Teva API

Israel

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

07

Hansoh Pharma

China

Israel

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Discovery on Target

Not Confirmed

Only 10 entries up to this point, click to access all

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USDMF

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NDC API

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Listed Suppliers

01

Rochem International Inc

U.S.A

CPhI Worldwide, Milan

Booth #3F18

Rochem, your partner in developing, sourcing, and supplying pharmaceutical & animal health ingredients of Chinese origin.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

Pemetrexed

About the Company : Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quali...

Established in 1994, Rochem is a distributor of pharmaceutical, food, nutritional and animal health ingredients to some of the largest companies in the world. It sources high-quality ingredients manufactured in China. Headquartered in the Hauppauge, New York, Rochem has 16 offices spread across the globe to cater to the needs of its customers. Rochem’s operations are fully cGMP compliant and has been audited by the USFDA as well as several multinational organizations. It also trains and audits its partners to ensure all of their technologies and systems are FDA-compliant.

02

Shandong Boyuan Pharmaceutical

China

CPhI Worldwide, Milan

Booth #3A142 & #3B136

Shandong Boyuan is a Chinese manufacturer of GMP & CEP APIs & pharmaceutical intermediates.

Contact Supplier

China

Virtual Booth

Digital Content

Pemetrexed

About the Company : We are one of the well-known manufacturers of key APIs & intermediates in China, with 20 years of experience & presence in 20+ countries. At Boyuan, we are committed to providing h...

We are one of the well-known manufacturers of key APIs & intermediates in China, with 20 years of experience & presence in 20+ countries. At Boyuan, we are committed to providing high-quality products & services. Formerly known as “Jinan Boyuan Chemical Co., Ltd” & “Shandong Boyuan Chemical Co., Ltd.” Boyuan was founded in June 2001. We have 2 manufacturing plants in the cities of Jiyang & Yucheng in Shandong Province, China & both are in line with the GMP standard, following a strict quality system & conforming with international standards. Boyuan is dedicated to anti-cancer, anti-fungal & other APIs & intermediates associated.

03

ChemWerth Inc

U.S.A

CPhI Worldwide, Milan

Booth #1D3

ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

Pemetrexed

About the Company : Established in 1982, ChemWerth is a US-headquartered full-service generic active pharmaceutical ingredient (API) development and supply company. ChemWerth offers cGMP-quality APIs ...

Established in 1982, ChemWerth is a US-headquartered full-service generic active pharmaceutical ingredient (API) development and supply company. ChemWerth offers cGMP-quality APIs to regulated markets worldwide and has exclusive partnerships for new product development, compliance support and secure supply chain logistics. ChemWerth has access to over 500 APIs and more than 30 manufacturing facilities in the US, Europe, India and China. ChemWerth acts as a regulatory agent for over 25 FDA-approved facilities and sells more than 100 products. It has established its presence in 38 countries. In 2020, ChemWerth filed its 500th DMF with the FDA.

04

Gonane Pharma

India

CPhI Worldwide, Milan

Attending

Gonane has API manufacturing expertise in new-age Corticosteroids, Hormones and other pharma raw materials.

Contact Supplier

India

Virtual Booth

Digital Content

Pemetrexed

About the Company : Gonane Pharma, is a contract pharmaceutical company located in Gujarat, India, specializing in the manufacturing and marketing of Corticosteroids, Hormones, Antivirals, and Oncolog...

Gonane Pharma, is a contract pharmaceutical company located in Gujarat, India, specializing in the manufacturing and marketing of Corticosteroids, Hormones, Antivirals, and Oncology products. The company's core strength lies in its dedicated team, and its promoters bring over 25 years of experience in manufacturing, promoting products, and managing audits for regulated markets such as the EU, Mexico, China, Korea, and Russia. GONANE PHARMA is actively engaged in discussions with Japanese customers and anticipates further expansion into additional markets.

05

HRV Global Life Sciences

India

CPhI Worldwide, Milan

Booth #3A25

HRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

Contact Supplier

India

Virtual Booth

Digital Content

Pemetrexed

About the Company : HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It...

HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It offers services such as sourcing, manufacturing and supply, helping partners enter new markets worldwide. Its strong partnerships with major players in the pharma and food additive industries help HRV Global effectively promote projects and products. HRV Global represents over 30 large Indian drugmakers, primarily targeting Europe, the US and the Middle East markets. Headquartered in India, HRV Global has offices in the US, Switzerland, Dubai, Lithuania & Turkey.

Portfolio PDF

Product Web Link

India

Luxepack

Not Confirmed

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API Reference Price

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