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Chemistry

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Also known as: 84380-01-8, 4-hydroxyphenyl a-d-glucopyranoside, Alpha arbutin, 4-hydroxyphenyl alpha-d-glucopyranoside, (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol, Alpha-d-glucopyranoside, 4-hydroxyphenyl
Molecular Formula
C12H16O7
Molecular Weight
272.25  g/mol
InChI Key
BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
FDA UNII
72VUP07IT5

Alpha-Arbutin
-arbutin is a natural product found in Rhodiola chrysanthemifolia, Rhodiola sacra, and other organisms with data available.
1 2D Structure

Alpha-Arbutin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol
2.1.2 InChI
InChI=1S/C12H16O7/c13-5-8-9(15)10(16)11(17)12(19-8)18-7-3-1-6(14)2-4-7/h1-4,8-17H,5H2/t8-,9-,10+,11-,12+/m1/s1
2.1.3 InChI Key
BJRNKVDFDLYUGJ-ZIQFBCGOSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1O)OC2C(C(C(C(O2)CO)O)O)O
2.1.5 Isomeric SMILES
C1=CC(=CC=C1O)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
2.2 Other Identifiers
2.2.1 UNII
72VUP07IT5
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 84380-01-8

2. 4-hydroxyphenyl A-d-glucopyranoside

3. Alpha Arbutin

4. 4-hydroxyphenyl Alpha-d-glucopyranoside

5. (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)oxane-3,4,5-triol

6. Alpha-d-glucopyranoside, 4-hydroxyphenyl

7. 72vup07it5

8. Chebi:29710

9. Pubchem16460

10. Ac1l4kbi

11. 4-hydroxyphenyl-alpha-d-glucopyranoside

12. Unii-72vup07it5

13. Alpha-arbutoside

14. A-arbutin

15. Mfcd09838262

16. I+/--arbutin

17. Oristar Aat

18. .alpha.-arbutin

19. Alpha-arbutin [inci]

20. Schembl435261

21. Chembl226495

22. Alpha-arbutin [who-dd]

23. 4-hydroxyphenyl-d-lucopyranoside

24. F Inverted Question Mark-arbutin

25. Dtxsid20233358

26. Alpha-arbutin, Analytical Standard

27. Amy22497

28. Hy-n3002

29. Zinc4102324

30. A-d-glucopyranoside, 4-hydroxyphenyl

31. S5112

32. Akos015905235

33. Ccg-267174

34. Db14109

35. N-cyclopropyl-n-hydroxyguanidine

36. (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydro-2h-pyran-3,4,5-triol

37. (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol

38. Ac-34884

39. As-15466

40. Cs-0022901

41. P-hydroxyphenyl-.alpha.-d-glucopyranoside

42. 4-hydroxyphenyl-.alpha.-d-glucopyranoside

43. A840768

44. W-203913

45. Q27110235

46. (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-(4-hydroxyphenoxy)tetrahydropyran-3,4,5-triol;alpha-arbutin

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 272.25 g/mol
Molecular Formula C12H16O7
XLogP3-0.7
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass272.08960285 g/mol
Monoisotopic Mass272.08960285 g/mol
Topological Polar Surface Area120 Ų
Heavy Atom Count19
Formal Charge0
Complexity279
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Alpha-Arbutin Manufacturers

A Alpha-Arbutin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Alpha-Arbutin, including repackagers and relabelers. The FDA regulates Alpha-Arbutin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Alpha-Arbutin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Alpha-Arbutin Suppliers

A Alpha-Arbutin supplier is an individual or a company that provides Alpha-Arbutin active pharmaceutical ingredient (API) or Alpha-Arbutin finished formulations upon request. The Alpha-Arbutin suppliers may include Alpha-Arbutin API manufacturers, exporters, distributors and traders.

Alpha-Arbutin GMP

Alpha-Arbutin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Alpha-Arbutin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Alpha-Arbutin GMP manufacturer or Alpha-Arbutin GMP API supplier for your needs.

Alpha-Arbutin CoA

A Alpha-Arbutin CoA (Certificate of Analysis) is a formal document that attests to Alpha-Arbutin's compliance with Alpha-Arbutin specifications and serves as a tool for batch-level quality control.

Alpha-Arbutin CoA mostly includes findings from lab analyses of a specific batch. For each Alpha-Arbutin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Alpha-Arbutin may be tested according to a variety of international standards, such as European Pharmacopoeia (Alpha-Arbutin EP), Alpha-Arbutin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Alpha-Arbutin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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