Find Alpha-Endorphin manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

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KDMF

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NDC API

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0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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DRUG PRODUCT COMPOSITIONS

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0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

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API REF. PRICE (USD/KG)

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Chemistry

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Also known as: 59004-96-5, 61512-76-3, Endorphin, alpha, Lipotropin 61-76, A-endorphin, Alpha -endorphin
Molecular Formula
C77H120N18O26S
Molecular Weight
1745.9  g/mol
InChI Key
NXSIJWJXMWBCBX-NWKQFZAZSA-N

Alpha-Endorphin
An endogenous opioid peptide derived from BETA-LIPOTROPIN of the pro-opiomelanocortin (POMC) system. It is the 16-amino acid sequence of the N-terminal of BETA-ENDORPHIN and differs from GAMMA-ENDORPHIN by one amino acid (beta-endorphin 1-17).
1 2D Structure

Alpha-Endorphin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4S)-5-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S,3R)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(1S,2R)-1-carboxy-2-hydroxypropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoic acid
2.1.2 InChI
InChI=1S/C77H120N18O26S/c1-38(2)31-51(70(113)91-60(39(3)4)74(117)94-63(42(7)100)77(120)121)88-73(116)55-18-14-29-95(55)76(119)62(41(6)99)93-67(110)48(23-25-56(80)102)85-71(114)53(36-96)89-65(108)47(17-12-13-28-78)84-66(109)49(24-26-59(105)106)86-72(115)54(37-97)90-75(118)61(40(5)98)92-68(111)50(27-30-122-8)87-69(112)52(33-43-15-10-9-11-16-43)83-58(104)35-81-57(103)34-82-64(107)46(79)32-44-19-21-45(101)22-20-44/h9-11,15-16,19-22,38-42,46-55,60-63,96-101H,12-14,17-18,23-37,78-79H2,1-8H3,(H2,80,102)(H,81,103)(H,82,107)(H,83,104)(H,84,109)(H,85,114)(H,86,115)(H,87,112)(H,88,116)(H,89,108)(H,90,118)(H,91,113)(H,92,111)(H,93,110)(H,94,117)(H,105,106)(H,120,121)/t40-,41-,42-,46+,47+,48+,49+,50+,51+,52+,53+,54+,55+,60+,61+,62+,63+/m1/s1
2.1.3 InChI Key
NXSIJWJXMWBCBX-NWKQFZAZSA-N
2.1.4 Canonical SMILES
CC(C)CC(C(=O)NC(C(C)C)C(=O)NC(C(C)O)C(=O)O)NC(=O)C1CCCN1C(=O)C(C(C)O)NC(=O)C(CCC(=O)N)NC(=O)C(CO)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C(CCSC)NC(=O)C(CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)C(CC3=CC=C(C=C3)O)N
2.1.5 Isomeric SMILES
C[C@H]([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)CNC(=O)CNC(=O)[C@H](CC3=CC=C(C=C3)O)N)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Alpha Endorphin

2. Beta-endorphin (1-16)

3. Endorphin, Alpha

2.2.2 Depositor-Supplied Synonyms

1. 59004-96-5

2. 61512-76-3

3. Endorphin, Alpha

4. Lipotropin 61-76

5. A-endorphin

6. Alpha -endorphin

7. Alpha-endorphin, Human

8. Chembl255300

9. Mfcd00076381

10. Akos037645059

11. Lph(61-76)

12. Alpha-endorphin Human, >=97% (hplc)

13. As-56652

14. Q4734927

15. H-tyr-gly-gly-phe-met-thr-ser-glu-lys-ser-gln-thr-pro-leu-val-thr-oh

2.3 Create Date
2007-07-04
3 Chemical and Physical Properties
Molecular Weight 1745.9 g/mol
Molecular Formula C77H120N18O26S
XLogP3-9.7
Hydrogen Bond Donor Count25
Hydrogen Bond Acceptor Count29
Rotatable Bond Count55
Exact Mass1744.83418718 g/mol
Monoisotopic Mass1744.83418718 g/mol
Topological Polar Surface Area744 Ų
Heavy Atom Count122
Formal Charge0
Complexity3520
Isotope Atom Count0
Defined Atom Stereocenter Count17
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Neurotransmitter Agents

Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function. (See all compounds classified as Neurotransmitter Agents.)


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Looking for 61512-76-3 / Alpha-Endorphin API manufacturers, exporters & distributors?

Alpha-Endorphin manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Alpha-Endorphin API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Alpha-Endorphin manufacturer or Alpha-Endorphin supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Alpha-Endorphin manufacturer or Alpha-Endorphin supplier.

PharmaCompass also assists you with knowing the Alpha-Endorphin API Price utilized in the formulation of products. Alpha-Endorphin API Price is not always fixed or binding as the Alpha-Endorphin Price is obtained through a variety of data sources. The Alpha-Endorphin Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Alpha-Endorphin

Synonyms

59004-96-5, 61512-76-3, Endorphin, alpha, Lipotropin 61-76, A-endorphin, Alpha -endorphin

Cas Number

61512-76-3

About Alpha-Endorphin

An endogenous opioid peptide derived from BETA-LIPOTROPIN of the pro-opiomelanocortin (POMC) system. It is the 16-amino acid sequence of the N-terminal of BETA-ENDORPHIN and differs from GAMMA-ENDORPHIN by one amino acid (beta-endorphin 1-17).

alpha Endorphin Manufacturers

A alpha Endorphin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of alpha Endorphin, including repackagers and relabelers. The FDA regulates alpha Endorphin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. alpha Endorphin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

alpha Endorphin Suppliers

A alpha Endorphin supplier is an individual or a company that provides alpha Endorphin active pharmaceutical ingredient (API) or alpha Endorphin finished formulations upon request. The alpha Endorphin suppliers may include alpha Endorphin API manufacturers, exporters, distributors and traders.

alpha Endorphin GMP

alpha Endorphin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of alpha Endorphin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right alpha Endorphin GMP manufacturer or alpha Endorphin GMP API supplier for your needs.

alpha Endorphin CoA

A alpha Endorphin CoA (Certificate of Analysis) is a formal document that attests to alpha Endorphin's compliance with alpha Endorphin specifications and serves as a tool for batch-level quality control.

alpha Endorphin CoA mostly includes findings from lab analyses of a specific batch. For each alpha Endorphin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

alpha Endorphin may be tested according to a variety of international standards, such as European Pharmacopoeia (alpha Endorphin EP), alpha Endorphin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (alpha Endorphin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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