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Chemistry

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Also known as: 17199-58-5, Alphacemethadone, .alpha.-d-acetylmethadol, Bxf83s0hel, Acscn-9603, Ids-na-008
Molecular Formula
C23H31NO2
Molecular Weight
353.5  g/mol
InChI Key
XBMIVRRWGCYBTQ-XMSQKQJNSA-N
FDA UNII
BXF83S0HEL

Alphacetylmethadol
A narcotic analgesic with a long onset and duration of action.
1 2D Structure

Alphacetylmethadol

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(3R,6R)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate
2.1.2 InChI
InChI=1S/C23H31NO2/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h7-16,18,22H,6,17H2,1-5H3/t18-,22-/m1/s1
2.1.3 InChI Key
XBMIVRRWGCYBTQ-XMSQKQJNSA-N
2.1.4 Canonical SMILES
CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C
2.1.5 Isomeric SMILES
CC[C@H](C(C[C@@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C
2.2 Other Identifiers
2.2.1 UNII
BXF83S0HEL
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (3r,6r)-3-acetoxy-6-dimethylamino-4,4-diphenylheptane

2. 6-(dimethylamino)-4,4-diphenyl-3-heptanol Acetate

3. Acemethadone

4. Acetylmethadol

5. Amidolacetate

6. Dimepheptanol

7. Laam

8. Levo Alpha Acetylmethadol

9. Levo-alpha-acetylmethadol

10. Levoacetylmethadol

11. Levomethadyl

12. Levomethadyl Acetate

13. Levomethadyl Acetate Hydrochloride

14. Methadol

15. Methadyl Acetate

16. Orlaam

2.3.2 Depositor-Supplied Synonyms

1. 17199-58-5

2. Alphacemethadone

3. .alpha.-d-acetylmethadol

4. Bxf83s0hel

5. Acscn-9603

6. Ids-na-008

7. (3r,6r)-3-acetoxy-6-dimethylamino-4,4-diphenylheptane

8. Alfacetilmetadol

9. Alfacetilmetadolo

10. Alfacetimethadone

11. Alphacetylmethadolum

12. Alpha-d-acetylmethadol

13. Alfacetilmetadolo [dcit]

14. Unii-bxf83s0hel

15. Alfacetilmetadol [inn-spanish]

16. Alphacetylmethadolum [inn-latin]

17. Alphacetylmethadol [inn:ban:dcf]

18. Schembl518398

19. Alpha-3-acetoxy-6-dimethylamino-4,4-diphenylheptane

20. Alphacetylmethadol [inn]

21. Dea No. 9603

22. (3r,6r)-6-dimethylamino-4,4-diphenyl-3-heptyl Acetat

23. Alpha-1-ethyl-4-dimethylamino-2,2-diphenylpentylacetat

24. Chembl2107793

25. Dtxsid70169198

26. [(3r,6r)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] Acetate

27. Zinc2007680

28. Bdbm50223637

29. Db01555

30. Benzeneethanol, Beta-((2r)-2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, Acetate (ester), (alphar)-

31. Benzeneethanol, Beta-(2-(dimethylamino)propyl)-alpha-ethyl-beta-phenyl-, Acetate (ester), (r-(r*,r*))-

32. Q4735230

33. .alpha.-3-acetoxy-6-dimethylamino-4,4-diphenylheptane

34. 3-heptanol, 6-(dimethylamino)-4,4-diphenyl-, Acetate (ester), (3r,6r)-(+)-

35. Alpha-cetylmethadol (except Levo-alpha-cetylmethadol Also Known As Levo-alpha-acetylmethadol, Levomethadyl Acetate, Or Laam)

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 353.5 g/mol
Molecular Formula C23H31NO2
XLogP34.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count9
Exact Mass353.235479232 g/mol
Monoisotopic Mass353.235479232 g/mol
Topological Polar Surface Area29.5 Ų
Heavy Atom Count26
Formal Charge0
Complexity404
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Analgesics, Opioid

Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)


4.2 Metabolism/Metabolites

Alphacetylmethadol has known human metabolites that include norLAAM.

S73 | METXBIODB | Metabolite Reaction Database from BioTransformer | DOI:10.5281/zenodo.4056560


ABOUT THIS PAGE

Alphacetylmethadol Manufacturers

A Alphacetylmethadol manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Alphacetylmethadol, including repackagers and relabelers. The FDA regulates Alphacetylmethadol manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Alphacetylmethadol API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Alphacetylmethadol Suppliers

A Alphacetylmethadol supplier is an individual or a company that provides Alphacetylmethadol active pharmaceutical ingredient (API) or Alphacetylmethadol finished formulations upon request. The Alphacetylmethadol suppliers may include Alphacetylmethadol API manufacturers, exporters, distributors and traders.

click here to find a list of Alphacetylmethadol suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Alphacetylmethadol USDMF

A Alphacetylmethadol DMF (Drug Master File) is a document detailing the whole manufacturing process of Alphacetylmethadol active pharmaceutical ingredient (API) in detail. Different forms of Alphacetylmethadol DMFs exist exist since differing nations have different regulations, such as Alphacetylmethadol USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Alphacetylmethadol DMF submitted to regulatory agencies in the US is known as a USDMF. Alphacetylmethadol USDMF includes data on Alphacetylmethadol's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Alphacetylmethadol USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Alphacetylmethadol suppliers with USDMF on PharmaCompass.

Alphacetylmethadol GMP

Alphacetylmethadol Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Alphacetylmethadol GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Alphacetylmethadol GMP manufacturer or Alphacetylmethadol GMP API supplier for your needs.

Alphacetylmethadol CoA

A Alphacetylmethadol CoA (Certificate of Analysis) is a formal document that attests to Alphacetylmethadol's compliance with Alphacetylmethadol specifications and serves as a tool for batch-level quality control.

Alphacetylmethadol CoA mostly includes findings from lab analyses of a specific batch. For each Alphacetylmethadol CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Alphacetylmethadol may be tested according to a variety of international standards, such as European Pharmacopoeia (Alphacetylmethadol EP), Alphacetylmethadol JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Alphacetylmethadol USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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