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Chemistry

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Also known as: Altizide, 5588-16-9, (-)-altizide, Altizide, (+)-, (+)-altizide, Althiazide [usan]
Molecular Formula
C11H14ClN3O4S3
Molecular Weight
383.9  g/mol
InChI Key
VGLGVJVUHYTIIU-UHFFFAOYSA-N
FDA UNII
D9KLS88BLV

Althiazide
Althiazide is an agent, also known as altizide, belonging to the class of thiazide diuretics with antihypertensive activity.
1 2D Structure

Althiazide

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2H-16,2,4-benzothiadiazine-7-sulfonamide
2.1.2 InChI
InChI=1S/C11H14ClN3O4S3/c1-2-3-20-6-11-14-8-4-7(12)9(21(13,16)17)5-10(8)22(18,19)15-11/h2,4-5,11,14-15H,1,3,6H2,(H2,13,16,17)
2.1.3 InChI Key
VGLGVJVUHYTIIU-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C=CCSCC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
2.2 Other Identifiers
2.2.1 UNII
D9KLS88BLV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 3-((allylthio)methyl)-6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide-1,1-dioxide

2. Altizide

3. Altozide

2.3.2 Depositor-Supplied Synonyms

1. Altizide

2. 5588-16-9

3. (-)-altizide

4. Altizide, (+)-

5. (+)-altizide

6. Althiazide [usan]

7. Altizide, (-)-

8. 6-chloro-3,4-dihydro-3-[(2-propenylthio)methyl]-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

9. Altizide [inn]

10. 3-((allylthio)methyl)-6-chloro-3,4-dihydro-2h-benzo[e][1,2,4]thiadiazine-7-sulfonamide 1,1-dioxide

11. D9kls88blv

12. 133562-97-7

13. 133585-76-9

14. Nsc-757786

15. Gi8cb72b0d

16. Ji3zo158in

17. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propen-1-ylthio)methyl)-, 1,1-dioxide, (+)-

18. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propen-1-ylthio)methyl)-, 1,1-dioxide, (-)-

19. P-1779

20. Altizide (inn)

21. Althiazide (usan)

22. Ncgc00094855-01

23. Altizida

24. Dsstox_cid_25857

25. Dsstox_rid_81178

26. Dsstox_gsid_45857

27. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-((2-propenylthio)methyl)-, 1,1-dioxide

28. 3-((allylthio)methyl)-6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

29. 3-[(allylthio)methyl]-6-chloro-3,4-dihydro-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

30. Altizidum

31. Altizidum [inn-latin]

32. Sr-05000001753

33. Altizida [inn-spanish]

34. Unii-d9kls88blv

35. Unii-gi8cb72b0d

36. Unii-ji3zo158in

37. Althiazide-[d5]

38. Prestwick_43

39. 6-chloro-1,1-dioxo-3-(prop-2-enylsulfanylmethyl)-3,4-dihydro-2h-1lambda6,2,4-benzothiadiazine-7-sulfonamide

40. Cas-5588-16-9

41. Einecs 226-994-8

42. Cb 8093

43. Spectrum_001104

44. Starbld0016521

45. Specplus_000833

46. Prestwick0_000721

47. Prestwick1_000721

48. Prestwick2_000721

49. Prestwick3_000721

50. Spectrum2_001367

51. Spectrum3_000902

52. Spectrum4_000999

53. Spectrum5_001725

54. Altizide [mart.]

55. Altizide [who-dd]

56. P 1779

57. Bspbio_000642

58. Kbiogr_001437

59. Kbioss_001584

60. Mls002153973

61. Divk1c_001031

62. Divk1c_006929

63. Schembl124525

64. Spectrum1500804

65. Spbio_001294

66. Spbio_002581

67. Altizide [ep Impurity]

68. Bpbio1_000708

69. Chembl599870

70. Altizide [ep Monograph]

71. Dtxsid3045857

72. Chebi:91768

73. Hms503o03

74. Kbio1_001031

75. Kbio1_001873

76. Kbio2_001584

77. Kbio2_004152

78. Kbio2_006720

79. Kbio3_001844

80. Ninds_001031

81. Hms1570a04

82. Hms1921i12

83. Hms2092k18

84. Hms2097a04

85. Hms2233o21

86. Hms3373k04

87. Hms3714a04

88. Pharmakon1600-01500804

89. Hy-b1254

90. Tox21_111347

91. Ccg-38982

92. Nsc757786

93. Akos027381757

94. Tox21_111347_1

95. Nsc 757786

96. 3-allylthiomethyl-6-chlor-3,4-dihydro-2h-1,2,4-benzothiadiazin-7-sulfonamid 1,1-dioxid

97. Idi1_001031

98. Smp1_000012

99. Ncgc00094855-02

100. Ncgc00094855-03

101. Ncgc00094855-06

102. 2h-1,2,4-benzothiadiazine-7-sulfonamide,6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide

103. 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-2h-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

104. Smr001233310

105. Sbi-0052594.p002

106. Db-052814

107. Ab00053099

108. Cs-0013046

109. Ft-0635778

110. D02838

111. Ab00053099_08

112. Sr-05000001753-1

113. Sr-05000001753-3

114. Brd-a56675431-001-04-0

115. Brd-a56675431-001-07-3

116. Altizide, European Pharmacopoeia (ep) Reference Standard

117. 6-chloro-3,4-dihydro-3-((2-propenylthio)methyl)-2h-1,2,4-benzothiadiazine-7-sulfonamide

118. 2h-1,2,4-benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide

119. 6-chloro-1,1-dioxo-3-[(prop-2-enylthio)methyl]-3,4-dihydro-2h-1$l;{6},2,4-benzothiadiazine-7-sulfonamide

120. 6-chloro-3,4-dihydro-3-[(2-propenylthio)methyl]-2h-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 383.9 g/mol
Molecular Formula C11H14ClN3O4S3
XLogP30.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count8
Rotatable Bond Count5
Exact Mass382.9834972 g/mol
Monoisotopic Mass382.9834972 g/mol
Topological Polar Surface Area160 Ų
Heavy Atom Count22
Formal Charge0
Complexity614
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

C03EA04

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355


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Looking for 133562-97-7 / Althiazide API manufacturers, exporters & distributors?

Althiazide manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Althiazide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Althiazide manufacturer or Althiazide supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Althiazide manufacturer or Althiazide supplier.

PharmaCompass also assists you with knowing the Althiazide API Price utilized in the formulation of products. Althiazide API Price is not always fixed or binding as the Althiazide Price is obtained through a variety of data sources. The Althiazide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Althiazide

Synonyms

Altizide, 5588-16-9, (-)-altizide, Altizide, (+)-, (+)-altizide, Althiazide [usan]

Cas Number

133562-97-7

Unique Ingredient Identifier (UNII)

D9KLS88BLV

About Althiazide

Althiazide is an agent, also known as altizide, belonging to the class of thiazide diuretics with antihypertensive activity.

Althiazide Manufacturers

A Althiazide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Althiazide, including repackagers and relabelers. The FDA regulates Althiazide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Althiazide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Althiazide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Althiazide Suppliers

A Althiazide supplier is an individual or a company that provides Althiazide active pharmaceutical ingredient (API) or Althiazide finished formulations upon request. The Althiazide suppliers may include Althiazide API manufacturers, exporters, distributors and traders.

click here to find a list of Althiazide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Althiazide USDMF

A Althiazide DMF (Drug Master File) is a document detailing the whole manufacturing process of Althiazide active pharmaceutical ingredient (API) in detail. Different forms of Althiazide DMFs exist exist since differing nations have different regulations, such as Althiazide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Althiazide DMF submitted to regulatory agencies in the US is known as a USDMF. Althiazide USDMF includes data on Althiazide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Althiazide USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Althiazide suppliers with USDMF on PharmaCompass.

Althiazide GMP

Althiazide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Althiazide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Althiazide GMP manufacturer or Althiazide GMP API supplier for your needs.

Althiazide CoA

A Althiazide CoA (Certificate of Analysis) is a formal document that attests to Althiazide's compliance with Althiazide specifications and serves as a tool for batch-level quality control.

Althiazide CoA mostly includes findings from lab analyses of a specific batch. For each Althiazide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Althiazide may be tested according to a variety of international standards, such as European Pharmacopoeia (Althiazide EP), Althiazide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Althiazide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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