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    Renejix: CDMO with expertise in small molecule oral dosage, delivery tech, and multi-modality manufacturing.

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    SPI Pharma has been solving formulation challenges using superior functional materials.

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    Ribobay has expertise in oligonucleotides from siRNA, Antisense Oligonucleotides, miRNAs, and aptamers & Oligonucleotides CXOs.

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    Chemistry

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    Also known as:
    Molecular Formula
    C18H14N4O5S
    Molecular Weight
    398.4  g/mol
    InChI Key
    OQANPHBRHBJGNZ-BKUYFWCQSA-N
    Sulfasalazine
    1 2D Structure

    Sulfasalazine

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (3Z)-6-oxo-3-[[4-(pyridin-2-ylsulfamoyl)phenyl]hydrazinylidene]cyclohexa-1,4-diene-1-carboxylic acid
    2.1.2 InChI
    InChI=1S/C18H14N4O5S/c23-16-9-6-13(11-15(16)18(24)25)21-20-12-4-7-14(8-5-12)28(26,27)22-17-3-1-2-10-19-17/h1-11,20H,(H,19,22)(H,24,25)/b21-13-
    2.1.3 InChI Key
    OQANPHBRHBJGNZ-BKUYFWCQSA-N
    2.1.4 Canonical SMILES
    C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)NN=C3C=CC(=O)C(=C3)C(=O)O
    2.1.5 Isomeric SMILES
    C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N/N=C\3/C=CC(=O)C(=C3)C(=O)O
    2.2 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 398.4 g/mol
    Molecular Formula C18H14N4O5S
    XLogP32.3
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count9
    Rotatable Bond Count6
    Exact Mass398.06849073 g/mol
    Monoisotopic Mass398.06849073 g/mol
    Topological Polar Surface Area146 A^2
    Heavy Atom Count28
    Formal Charge0
    Complexity804
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count1
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 6  
    Drug NameAzulfidine
    PubMed HealthSalicylate (Oral route, Rectal route)
    Drug ClassesAntirheumatic, Gastrointestinal Agent
    Drug LabelAZULFIDINE EN-tabs Tablets contain sulfasalazine, formulated in a delayed release tablet (enteric-coated), 500 mg, for oral administration.AZULFIDINE EN-tabs Tablets are film coated with cellulose acetate phthalate to retard disintegration of the tab...
    Active IngredientSulfasalazine
    Dosage FormTablet; Suspension
    RouteOral
    Strength500mg; 250mg/5ml
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    2 of 6  
    Drug NameAzulfidine en-tabs
    PubMed HealthSulfasalazine (By mouth)
    Drug LabelAZULFIDINE EN-tabs Tablets contain sulfasalazine, formulated in a delayed release tablet (enteric-coated), 500 mg, for oral administration.AZULFIDINE EN-tabs Tablets are film coated with cellulose acetate phthalate to retard disintegration of the tab...
    Active IngredientSulfasalazine
    Dosage FormTablet; Tablet, delayed release
    Routeoral; Oral
    Strength500mg
    Market StatusPrescription
    CompanyPharmacia Upjohn; Pharmacia And Upjohn

    3 of 6  
    Drug NameSulfasalazine
    Drug LabelSulfasalazine Tablets USP, 500 mg for Oral AdministrationTherapeutic classification: Anti-inflammatory agent.Chemical designation: 5-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid.Chemical Structure:The molecular weight of sulfasalazine is 398.39....
    Active IngredientSulfasalazine
    Dosage FormTablet; Tablet, delayed release
    RouteOral
    Strength500mg
    Market StatusPrescription
    CompanyVintage Pharms; Watson Labs

    4 of 6  
    Drug NameAzulfidine
    PubMed HealthSalicylate (Oral route, Rectal route)
    Drug ClassesAntirheumatic, Gastrointestinal Agent
    Drug LabelAZULFIDINE EN-tabs Tablets contain sulfasalazine, formulated in a delayed release tablet (enteric-coated), 500 mg, for oral administration.AZULFIDINE EN-tabs Tablets are film coated with cellulose acetate phthalate to retard disintegration of the tab...
    Active IngredientSulfasalazine
    Dosage FormTablet; Suspension
    RouteOral
    Strength500mg; 250mg/5ml
    Market StatusPrescription
    CompanyPharmacia And Upjohn

    5 of 6  
    Drug NameAzulfidine en-tabs
    PubMed HealthSulfasalazine (By mouth)
    Drug LabelAZULFIDINE EN-tabs Tablets contain sulfasalazine, formulated in a delayed release tablet (enteric-coated), 500 mg, for oral administration.AZULFIDINE EN-tabs Tablets are film coated with cellulose acetate phthalate to retard disintegration of the tab...
    Active IngredientSulfasalazine
    Dosage FormTablet; Tablet, delayed release
    Routeoral; Oral
    Strength500mg
    Market StatusPrescription
    CompanyPharmacia Upjohn; Pharmacia And Upjohn

    6 of 6  
    Drug NameSulfasalazine
    Drug LabelSulfasalazine Tablets USP, 500 mg for Oral AdministrationTherapeutic classification: Anti-inflammatory agent.Chemical designation: 5-[[p-(2-Pyridylsulfamoyl)phenyl]azo]salicylic acid.Chemical Structure:The molecular weight of sulfasalazine is 398.39....
    Active IngredientSulfasalazine
    Dosage FormTablet; Tablet, delayed release
    RouteOral
    Strength500mg
    Market StatusPrescription
    CompanyVintage Pharms; Watson Labs

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    15-Jan-2021
    27-Sep-2024
    KGS
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