Find Aluminum Monostearate API manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 7047-84-9, Dibasic aluminum stearate, Dihydroxyaluminum stearate, Dihydroxy(stearato)aluminium, Dihydroxy(stearato)aluminum, Dihydroxyaluminium stearate, pure
Molecular Formula
C18H39AlO4
Molecular Weight
346.5  g/mol
InChI Key
OIPZNTLJVJGRCI-UHFFFAOYSA-M

Aluminum Monostearate API
Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics. While considered safe for use, extensive usage may result in aluminum accumulation.
1 2D Structure

Aluminum Monostearate API

2 Identification
2.1 Computed Descriptors
2.1.1 InChI
InChI=1S/C18H36O2.Al.2H2O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20;;;/h2-17H2,1H3,(H,19,20);;2*1H2/q;+1;;/p-1
2.1.2 InChI Key
OIPZNTLJVJGRCI-UHFFFAOYSA-M
2.1.3 Canonical SMILES
CCCCCCCCCCCCCCCCCC(=O)O[Al].O.O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Aluminum Tristearate

2. Ammonium Stearate

3. Calcium Stearate

4. Magnesium Stearate

5. Octadecanoic Acid

6. Sodium Stearate

7. Stearic Acid

8. Zinc Stearate

2.2.2 Depositor-Supplied Synonyms

1. 7047-84-9

2. Dibasic Aluminum Stearate

3. Dihydroxyaluminum Stearate

4. Dihydroxy(stearato)aluminium

5. Dihydroxy(stearato)aluminum

6. Dihydroxyaluminium Stearate, Pure

7. Chebi:31197

8. Ncgc00160596-02

9. Aluminum, Monostearate

10. Aluminum, Dihydroxide Stearate

11. Einecs 230-325-5

12. Aluminum, Dihydroxy(stearato)-

13. Aluminum Dihydroxide Stearate

14. Unii-p9bc99461e

15. Aluminum Dextran

16. Aluminum Monostearate [jan:nf]

17. Stearic Acid Aluminum Dihydroxide Salt

18. Aluminum, Dihydroxy(octadecanoato-kappao)-

19. Aluminum, Dihydroxy(octadecanoato-.kappa.o)-

20. Schembl4101

21. Dsstox_cid_28623

22. Dsstox_rid_82893

23. Dsstox_gsid_48697

24. Chembl3185220

25. Dtxsid9048697

26. Dihydroxido(octadecanoato)aluminium

27. Aluminum Monostearate (jp17/nf)

28. Tox21_113090

29. Akos024319334

30. Db01375

31. Ncgc00160596-01

32. Ncgc00160596-03

33. Cas-7047-84-9

34. D01867

35. F20724

36. Sr-01000945248

37. Q4119955

38. Sr-01000945248-1

39. Aluminum Monostearate, Technical, ~75% (al), Powder

2.3 Create Date
2007-08-23
3 Chemical and Physical Properties
Molecular Weight 346.5 g/mol
Molecular Formula C18H39AlO4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count18
Exact Mass346.2663731 g/mol
Monoisotopic Mass346.2663731 g/mol
Topological Polar Surface Area28.3 Ų
Heavy Atom Count23
Formal Charge0
Complexity225
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 Mechanism of Action

Antacids perform a neutralization reaction, ie. they buffer gastric acid, raising the pH to reduce acidity in the stomach. When gastric hydrochloric acid reaches the nerves in the gasitrointestinal mucosa, they signal pain to the central nervous system. This happens when these nerves are exposed, as in peptic ulcers. The gastric acid may also reach ulcers in the esophagus or the duodenum. Other mechanisms may contribute, such as the effect of aluminum ions inhibiting smooth muscle cell contraction and delaying gastric emptying. Aluminum is known to bind troponin C (a muscle protein) and to interfere with voltage-dependent calcium transport. Aluminum also binds to and inhibits the activity of mitochondrial voltage gated channels (VDAC).


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Looking for 7047-84-9 / Aluminum Monostearate API API manufacturers, exporters & distributors?

Aluminum Monostearate API manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Aluminum Monostearate API API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Aluminum Monostearate API manufacturer or Aluminum Monostearate API supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Aluminum Monostearate API manufacturer or Aluminum Monostearate API supplier.

PharmaCompass also assists you with knowing the Aluminum Monostearate API API Price utilized in the formulation of products. Aluminum Monostearate API API Price is not always fixed or binding as the Aluminum Monostearate API Price is obtained through a variety of data sources. The Aluminum Monostearate API Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Aluminum Monostearate API

Synonyms

7047-84-9, Dibasic aluminum stearate, Dihydroxyaluminum stearate, Dihydroxy(stearato)aluminium, Dihydroxy(stearato)aluminum, Dihydroxyaluminium stearate, pure

Cas Number

7047-84-9

About Aluminum Monostearate API

Aluminium monostearate is a salt of stearic acid and aluminium with the molecular formula Al(OH)2C18H35O2. Also known as dihydroxyaluminium or dihydroxy(stearato)aluminium, it is used to form gels in the packaging of pharmaceuticals and in the preparation of colors for cosmetics. While considered safe for use, extensive usage may result in aluminum accumulation.

Aluminum Monostearate API Manufacturers

A Aluminum Monostearate API manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Aluminum Monostearate API, including repackagers and relabelers. The FDA regulates Aluminum Monostearate API manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Aluminum Monostearate API API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Aluminum Monostearate API Suppliers

A Aluminum Monostearate API supplier is an individual or a company that provides Aluminum Monostearate API active pharmaceutical ingredient (API) or Aluminum Monostearate API finished formulations upon request. The Aluminum Monostearate API suppliers may include Aluminum Monostearate API API manufacturers, exporters, distributors and traders.

Aluminum Monostearate API GMP

Aluminum Monostearate API Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Aluminum Monostearate API GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Aluminum Monostearate API GMP manufacturer or Aluminum Monostearate API GMP API supplier for your needs.

Aluminum Monostearate API CoA

A Aluminum Monostearate API CoA (Certificate of Analysis) is a formal document that attests to Aluminum Monostearate API's compliance with Aluminum Monostearate API specifications and serves as a tool for batch-level quality control.

Aluminum Monostearate API CoA mostly includes findings from lab analyses of a specific batch. For each Aluminum Monostearate API CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Aluminum Monostearate API may be tested according to a variety of international standards, such as European Pharmacopoeia (Aluminum Monostearate API EP), Aluminum Monostearate API JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Aluminum Monostearate API USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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