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Chemistry

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Also known as: 7784-30-7, Aluminum monophosphate, Phosphaljel, Aluminium phosphate, Monoaluminum phosphate, Aluminumphosphate
Molecular Formula
AlO4P
Molecular Weight
121.953  g/mol
InChI Key
ILRRQNADMUWWFW-UHFFFAOYSA-K
FDA UNII
F92V3S521O

Aluminum Phosphate
1 2D Structure

Aluminum Phosphate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
aluminum;phosphate
2.1.2 InChI
InChI=1S/Al.H3O4P/c;1-5(2,3)4/h;(H3,1,2,3,4)/q+3;/p-3
2.1.3 InChI Key
ILRRQNADMUWWFW-UHFFFAOYSA-K
2.1.4 Canonical SMILES
[O-]P(=O)([O-])[O-].[Al+3]
2.2 Other Identifiers
2.2.1 UNII
F92V3S521O
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Aluminum Monophosphate

2. Aluminum Phosphate (3:1)

3. Aluminum Phosphate (3:2)

4. Aluminum Phosphate Dihydrate

5. Phosphalugel

2.3.2 Depositor-Supplied Synonyms

1. 7784-30-7

2. Aluminum Monophosphate

3. Phosphaljel

4. Aluminium Phosphate

5. Monoaluminum Phosphate

6. Aluminumphosphate

7. Aluminum Phosphate (1:1)

8. Phosphoric Acid, Aluminum Salt (1:1)

9. Aluminum Phosphate Gel

10. Aluminium Phosphate Gel

11. Aluminum Phosphate [usp]

12. Phosphalugel

13. F92v3s521o

14. Aluminum Acid Phosphate

15. Aluphos

16. Aluminum Phosphate (usp)

17. 56574-68-6

18. 98499-64-0

19. Aluminophosphoric Acid

20. Aluminum Phosphoric Acid

21. Aluminiumphosphat

22. Mfcd00003430

23. Aluminiumphosphat [german]

24. Aluminum Monophosphate; Aluminum Orthophosphate;phosphalutab; Phosphaluvet; Rehydraphos

25. Ffb 32

26. Aluminium Orthophosphate

27. Aluminium Phosphate, Pure

28. Einecs 232-056-9

29. Unii-f92v3s521o

30. Aluminium Orthophosphate, Natural

31. Phosphaljel (tn)

32. Phosphoric Acid, Aluminium Salt (1:1)

33. Aluminum Phosphate Powder

34. Aluminum Phosphate B111

35. Aluminum Phosphate B210

36. Ec 232-056-9

37. Aluminum Phosphate Suspension

38. Aluminum Phosphate, Puratronic

39. Aluminum Phosphate [mi]

40. Chembl3833315

41. Dtxsid5064839

42. Aluminum Phosphate [vandf]

43. Aluminium Phosphate (1:1)

44. Aluminium Phosphate [mart.]

45. Aluminium Phosphate [who-dd]

46. Akos015856690

47. Db14517

48. Aluminium Phosphate Gel [who-dd]

49. Aluminum Phosphate [usp Impurity]

50. Ft-0622223

51. Aluminium Phosphate Gel [ep Monograph]

52. D02862

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 121.953 g/mol
Molecular Formula AlO4P
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass121.9349589 g/mol
Monoisotopic Mass121.9349589 g/mol
Topological Polar Surface Area86.2 Ų
Heavy Atom Count6
Formal Charge0
Complexity36.8
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adjuvants, Immunologic

Substances that augment, stimulate, activate, potentiate, or modulate the immune response at either the cellular or humoral level. The classical agents (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contain bacterial antigens. Some are endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Their mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy of many biological response modifiers is related to their antigen-specific immunoadjuvanticity. (See all compounds classified as Adjuvants, Immunologic.)


Antacids

Substances that counteract or neutralize acidity of the GASTROINTESTINAL TRACT. (See all compounds classified as Antacids.)


4.2 ATC Code

A - Alimentary tract and metabolism

A02 - Drugs for acid related disorders

A02A - Antacids

A02AB - Aluminium compounds

A02AB03 - Aluminium phosphate


4.3 Mechanism of Action

Aluminum Acetate is an astringent. An astrignent is a chemical that tends to shrink or constrict body tissues, usually locally after topical medicinal application. The shrinkage or constriction is through osmotic flow of water (or other fluids) away from the area where the astringent was applied. Astringent medicines cause shrinkage of mucous membranes or exposed tissues and are often used internally to check discharge of blood serum or mucous secretions. This can happen with a sore throat, hemorrhages, diarrhea, or with peptic ulcers. Externally applied astringents, which cause mild coagulation of skin proteins, dry, harden, and protect the skin. Acne sufferers are often advised to use astringents if they have oily skin. Astringents also help heal stretch marks and other scars. Mild astringent solutions are used in the relief of such minor skin irritations as those resulting from superficial cuts, allergies, insect bites, or fungal infections such as athlete's foot.


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