Find Ambazone manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

0INTERMEDIATES

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

API REF. PRICE (USD/KG)

$
$ 0

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Regulatory FDF Prices

NA

API/FDF Prices: Book a Demo to
explore the features and consider
upgrading later

MARKET PLACE

0

FDF

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: 539-21-9, Faringosept, Ambazon, Anginon, Primal, Ambazona
Molecular Formula
C8H11N7S
Molecular Weight
237.29  g/mol
InChI Key
ANZIOUQAFBXNHU-UHFFFAOYSA-N
FDA UNII
BYK4592A3Q

Ambazone
Ambazone is an antiseptic agent with potential antibacterial and antileukemic activity. Although the exact mechanism of action remains to be fully elucidated, ambazone appears to interfere with the membrane-bound nucleotide system by increasing the intracellular concentration of cAMP in leukemia cells and macrophages, which potentially contributes to this agent's antineoplastic activity. Furthermore, this agent's affinity for various cellular targets, i.e. membranes, nucleic acids and proteins, may contribute to the overall antibacterial effect.
1 2D Structure

Ambazone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[4-[2-(diaminomethylidene)hydrazinyl]phenyl]iminothiourea
2.1.2 InChI
InChI=1S/C8H11N7S/c9-7(10)14-12-5-1-3-6(4-2-5)13-15-8(11)16/h1-4,12H,(H2,11,16)(H4,9,10,14)
2.1.3 InChI Key
ANZIOUQAFBXNHU-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1NN=C(N)N)N=NC(=S)N
2.2 Other Identifiers
2.2.1 UNII
BYK4592A3Q
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1,4-benzoquinone Guanylhydrazone Thiosemicarbazone

2. 1,4-benzoquinone Guanylhydrazone Thiosemicarbazone Monohydrochloride

2.3.2 Depositor-Supplied Synonyms

1. 539-21-9

2. Faringosept

3. Ambazon

4. Anginon

5. Primal

6. Ambazona

7. Ambazone [inn:ban:dcf]

8. Ambazone (inn)

9. Mls001240207

10. Inversal

11. Ivertol

12. 1,4-benzoquinone Guanylhydrazone Thiosemicarbazone

13. [4-[2-(diaminomethylidene)hydrazinyl]phenyl]iminothiourea

14. Byk4592a3q

15. Guanothiazon

16. ((4-oxo-2,5-cyclohexadien-1-ylidene)amino)guanidine Thiosemicarbazone

17. Ncgc00164514-01

18. Ambazonum

19. Promassol

20. Smr000674566

21. Ambazone [inn]

22. Ambazonum [inn-latin]

23. Ambazona [inn-spanish]

24. Hydrazinecarbothioamide, 2-(4-((aminoiminomethyl)hydrazono)-2,5-cyclohexadien-1-ylidene)-

25. Ccris 1926

26. Benzoquinone Guanylhydrazone Thiosemicarbazone

27. Hydrazinecarbothioamide, 2-[4-[(aminoiminomethyl)hydrazono]-2,5-cyclohexadien-1-ylidene]-

28. P-benzoquinone Amidinohydrazone Thiosemicarbazone

29. Dc 0572

30. Einecs 208-713-0

31. Unii-byk4592a3q

32. Faringosept (tn)

33. 1-amidinohydrazono-4-thiosemicarbazono-2,5-cyclohexadiene

34. 4-amidinohydrazono-2,5-cyclohexadien-1-on-thiosemicarbazon

35. Ambazone [mi]

36. P-benzoquinoneamidinohydrazonethiosemicarbazone

37. Ambazone [mart.]

38. Ambazone [who-dd]

39. Dsstox_cid_26407

40. Dsstox_rid_81587

41. Dsstox_gsid_46407

42. Schembl457920

43. Schembl1649608

44. Chembl1414870

45. Chembl2103762

46. Chembl3198213

47. Dtxsid3046407

48. Schembl11887782

49. Bdbm53352

50. Cid_1549158

51. Chebi:134962

52. Hms2231l21

53. Zinc1550965

54. Tox21_112149

55. Stl200147

56. Akos000622836

57. Akos002161802

58. Akos005197779

59. Guanidine, ((4-oxo-2,5-cyclohexadien-1-ylidene)amino)-, Thiosemicarbazone

60. Db13697

61. Ncgc00164514-02

62. Cas-539-21-9

63. Ft-0661544

64. D07376

65. 539a219

66. Q414317

67. Sr-01000799157

68. Sr-01000799157-2

69. [4-(2-(diaminomethylidene)hydrazino)phenyl]iminothiourea

70. [4-[n''-(diaminomethylene)hydrazino]phenyl]iminothiourea

71. [(4-{[(diaminomethylidene)amino]amino}phenyl)imino]thiourea

72. 1-[4-[2-[bis(azanyl)methylidene]hydrazinyl]phenyl]iminothiourea

73. {[4-(carbamimidamidoimino)cyclohexa-2,5-dien-1-ylidene]amino}thiourea

74. (2e)-2-{(4e)-4-[(aminocarbonothioyl)hydrazono]cyclohexa-2,5-dien-1-ylidene}hydrazinecarboximidamide

75. (2z)-2-[(4z)-4-(2-carbamimidoylhydrazinylidene)cyclohexa-2,5-dien-1-ylidene]hydrazinecarbothioamide

76. Hydrazinecarbothioamide, 2-(4-(2-(aminoiminomethyl)hydrazinylidene)-2,5-cyclohexadien-1-ylidene)-

77. N''-{(1z,4z)-4-[(aminocarbonothioyl)hydrazono]cyclohexa-2,5-dien-1-ylidene}carbonohydrazonic Diamide

2.4 Create Date
2005-07-11
3 Chemical and Physical Properties
Molecular Weight 237.29 g/mol
Molecular Formula C8H11N7S
XLogP30.7
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass237.07966455 g/mol
Monoisotopic Mass237.07966455 g/mol
Topological Polar Surface Area159 Ų
Heavy Atom Count16
Formal Charge0
Complexity289
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

R - Respiratory system

R02 - Throat preparations

R02A - Throat preparations

R02AA - Antiseptics

R02AA01 - Ambazone


Market Place

Do you need sourcing support? Ask us

ABOUT THIS PAGE

Looking for 539-21-9 / Ambazone API manufacturers, exporters & distributors?

Ambazone manufacturers, exporters & distributors 1

97

PharmaCompass offers a list of Ambazone API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Ambazone manufacturer or Ambazone supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Ambazone manufacturer or Ambazone supplier.

PharmaCompass also assists you with knowing the Ambazone API Price utilized in the formulation of products. Ambazone API Price is not always fixed or binding as the Ambazone Price is obtained through a variety of data sources. The Ambazone Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Ambazone

Synonyms

539-21-9, Faringosept, Ambazon, Anginon, Primal, Ambazona

Cas Number

539-21-9

Unique Ingredient Identifier (UNII)

BYK4592A3Q

About Ambazone

Ambazone is an antiseptic agent with potential antibacterial and antileukemic activity. Although the exact mechanism of action remains to be fully elucidated, ambazone appears to interfere with the membrane-bound nucleotide system by increasing the intracellular concentration of cAMP in leukemia cells and macrophages, which potentially contributes to this agent's antineoplastic activity. Furthermore, this agent's affinity for various cellular targets, i.e. membranes, nucleic acids and proteins, may contribute to the overall antibacterial effect.

Ambazone Manufacturers

A Ambazone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ambazone, including repackagers and relabelers. The FDA regulates Ambazone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ambazone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Ambazone Suppliers

A Ambazone supplier is an individual or a company that provides Ambazone active pharmaceutical ingredient (API) or Ambazone finished formulations upon request. The Ambazone suppliers may include Ambazone API manufacturers, exporters, distributors and traders.

Ambazone GMP

Ambazone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ambazone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ambazone GMP manufacturer or Ambazone GMP API supplier for your needs.

Ambazone CoA

A Ambazone CoA (Certificate of Analysis) is a formal document that attests to Ambazone's compliance with Ambazone specifications and serves as a tool for batch-level quality control.

Ambazone CoA mostly includes findings from lab analyses of a specific batch. For each Ambazone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ambazone may be tested according to a variety of international standards, such as European Pharmacopoeia (Ambazone EP), Ambazone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ambazone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty