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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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Europe

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Canada

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Australia

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South Africa

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Chemistry

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Also known as: 841301-32-4, Asp 2151, Asp2151, Amenamevir [inn], Asp-2151, 94x46kw4ae
Molecular Formula
C24H26N4O5S
Molecular Weight
482.6  g/mol
InChI Key
MNHNIVNAFBSLLX-UHFFFAOYSA-N
FDA UNII
94X46KW4AE

Amenamevir
Amenamevir is a novel helicase-primase inhibitor that is active against varicella-zoster virus and herpes simplex virus types 1 and 2. Amenamenir stabilizes the interaction between the helicase-primase and its DNA substrates, preventing the progression through helicase or primase catalytic cycles, thus interfering with viral DNA replication and viral growth.
1 2D Structure

Amenamevir

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-(2,6-dimethylphenyl)-N-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxoethyl]-1,1-dioxothiane-4-carboxamide
2.1.2 InChI
InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)
2.1.3 InChI Key
MNHNIVNAFBSLLX-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C(=CC=C1)C)N(CC(=O)NC2=CC=C(C=C2)C3=NOC=N3)C(=O)C4CCS(=O)(=O)CC4
2.2 Other Identifiers
2.2.1 UNII
94X46KW4AE
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Asp2151

2.3.2 Depositor-Supplied Synonyms

1. 841301-32-4

2. Asp 2151

3. Asp2151

4. Amenamevir [inn]

5. Asp-2151

6. 94x46kw4ae

7. N-(2-((4-(1,2,4-oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-n-(2,6-dimethylphenyl)tetrahydro-2h-thiopyran-4-carboxamide 1,1-dioxide

8. N-(2,6-dimethylphenyl)-n-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxoethyl]-1,1-dioxothiane-4-carboxamide

9. Unii-94x46kw4ae

10. Amenalief (tn)

11. Amenamevir [mi]

12. Amenamevir (jan/inn)

13. Amenamevir [jan]

14. Amenamevir [who-dd]

15. Schembl2238614

16. Chembl4297592

17. Dtxsid101027753

18. Bcp29135

19. Ex-a1700

20. S5552

21. Ccg-269570

22. Cs-8093

23. Db11701

24. Sb19732

25. Ncgc00538163-01

26. Ac-35855

27. Bs-17608

28. Hy-14809

29. D10564

30. D84108

31. Q27271708

32. 2-[n-(2,6-dimethylphenyl)-n-[(tetrahydro-2h-thiopyran 1,1-dioxide)-4-ylcarbonyl]amino]-4'-(1,2,4-oxadiazole-3-yl)acetoanilide

33. N-(2,6-dimethylphenyl)-n-(2-((4-(1,2,4-oxadiazol-3-yl)phenyl)amino)-2-oxoethyl)-1,1-dioxothiane-4-carboxamide

34. N-(2,6-dimethylphenyl)-n-(2-{[4-(1,2,4-oxadiazol-3-yl)phenyl]amino}-2-oxoethyl)tetrahydro-2h-thiopyran-4-carboxamide 1,1-dioxide

35. N-(2,6-dimethylphenyl)-n-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxo-ethyl]-1,1-dioxo-thiane-4-carboxamide

2.4 Create Date
2006-10-26
3 Chemical and Physical Properties
Molecular Weight 482.6 g/mol
Molecular Formula C24H26N4O5S
XLogP32.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass482.16239112 g/mol
Monoisotopic Mass482.16239112 g/mol
Topological Polar Surface Area131 Ų
Heavy Atom Count34
Formal Charge0
Complexity800
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

J - Antiinfectives for systemic use

J05 - Antivirals for systemic use

J05A - Direct acting antivirals

J05AX - Other antivirals

J05AX26 - Amenamevir


API SUPPLIERS

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01

Jinan Tantu Chemicals

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
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Virtual BoothJinan Tantu Chemicals offers customized R&D services & production of small molecule APIs & pharmaceutical intermediates.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Jinan Tantu Chemicals

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CF Pharma

Hungary

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
  • fda
  • EDQM
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Virtual BoothCF Pharma- skilled & highly experienced European API producer based in Hungary.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
CF Pharma

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Shandong Loncom Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
  • fda
  • EDQM
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Virtual BoothShandong Loncom is an R&D-focused manufacturer of Anti-cancer APIs.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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J&H CHEM

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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J&H CHEM

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Shenzhen Tianyuan Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Pharma, Lab & Chemical Expo
Not Confirmed
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Shenzhen Tianyuan Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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INTERMEDIATES SUPPLIERS

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  • fda
  • EDQM
  • WHO-GMP

Virtual BoothJinan Tantu Chemicals offers customized R&D services & production of small molecule APIs & pharmaceutical intermediates.

CAS Number : 89489-53-2

End Use API : Amenamevir

About The Company : Jinan Tantu Chemicals Co., Ltd. operates as a Contract Development and Manufacturing Organization (CDMO) that serves pharmaceutical companies worldwide. Our cor...

Jinan Tantu Chemicals

02

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothJinan Tantu Chemicals offers customized R&D services & production of small molecule APIs & pharmaceutical intermediates.

CAS Number : 64096-87-3

End Use API : Amenamevir

About The Company : Jinan Tantu Chemicals Co., Ltd. operates as a Contract Development and Manufacturing Organization (CDMO) that serves pharmaceutical companies worldwide. Our cor...

Jinan Tantu Chemicals

03

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothJinan Tantu Chemicals offers customized R&D services & production of small molecule APIs & pharmaceutical intermediates.

CAS Number : 59908-70-2

End Use API : Amenamevir

About The Company : Jinan Tantu Chemicals Co., Ltd. operates as a Contract Development and Manufacturing Organization (CDMO) that serves pharmaceutical companies worldwide. Our cor...

Jinan Tantu Chemicals

04

BIO Partnering at JPM
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BIO Partnering at JPM
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CAS Number : 64096-87-3

End Use API : Amenamevir

About The Company : Eyougene was incubated in Fudan Chemical and has grown into a leader in the field of chemical research and development, now based in the dynamic Lingang area of...

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FDF Dossiers

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Maruho

Japan
Biotech Showcase
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Maruho

Japan
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Amenamevir

Brand Name : Amenalief

Dosage Form : Tablet

Dosage Strength : 200MG

Packaging :

Approval Date :

Application Number :

Regulatory Info :

Registration Country : Japan

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ABOUT THIS PAGE

Amenamevir Manufacturers

A Amenamevir manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Amenamevir, including repackagers and relabelers. The FDA regulates Amenamevir manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Amenamevir API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Amenamevir manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Amenamevir Suppliers

A Amenamevir supplier is an individual or a company that provides Amenamevir active pharmaceutical ingredient (API) or Amenamevir finished formulations upon request. The Amenamevir suppliers may include Amenamevir API manufacturers, exporters, distributors and traders.

click here to find a list of Amenamevir suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Amenamevir GMP

Amenamevir Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Amenamevir GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Amenamevir GMP manufacturer or Amenamevir GMP API supplier for your needs.

Amenamevir CoA

A Amenamevir CoA (Certificate of Analysis) is a formal document that attests to Amenamevir's compliance with Amenamevir specifications and serves as a tool for batch-level quality control.

Amenamevir CoA mostly includes findings from lab analyses of a specific batch. For each Amenamevir CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Amenamevir may be tested according to a variety of international standards, such as European Pharmacopoeia (Amenamevir EP), Amenamevir JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Amenamevir USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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