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ACTIVE PHARMA INGREDIENTS

18 API Suppliers, 18 USDMF, 1 CEP/COS, 5 NDC API

18 API Suppliers
18 USDMF
1 CEP/COS
5 NDC API

DEVELOPMENTS

3 Drugs in Development

3 Drugs in Development

INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

308 FDF Dossiers, 166 FDA Orange Book, 42 Europe, 99 South Africa, 1 Listed Dossiers

308 FDF Dossiers
166 FDA Orange Book
42 Europe
99 South Africa
1 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

INJECTABLE;INJECTION - 10% (10GM/100ML), INJECTABLE;INJECTION - 6% (6GM/100ML), EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1440ML), EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1920ML), EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML ;105MG/100ML;3.5GM/100ML (2400ML), EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML ;147MG/100ML;3.9GM/100ML (1026ML), EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (1540ML), EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2053ML), EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2566ML)

drugProductComposition
INJECTABLE;INJECTION - 10% (10GM/100ML)
INJECTABLE;INJECTION - 6% (6GM/100ML)
EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1440ML)
EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1920ML)
EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML ;105MG/100ML;3.5GM/100ML (2400ML)
EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML ;147MG/100ML;3.9GM/100ML (1026ML)
EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (1540ML)
EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2053ML)
EMULSION;INTRAVENOUS - 3.3%;29MG/100ML;9.8GM/100ML;96MG/100ML;174MG/100ML;239MG/100ML;147MG/100ML;3.9GM/100ML (2566ML)

DIGITAL CONTENT

1 DATA COMPILATION #PharmaFlow, 10 NEWS #PharmaBuzz

media
1 DATA COMPILATION #PharmaFlow
10 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

42 Finished Drug Prices

globalSalesInformation
42 Finished Drug Prices

REF. STANDARDS & IMPURITIES

1 EDQM

otherSolutions
1 EDQM

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

1INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

308

FDF Dossiers

166

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

3DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as: Amino acids, essential, Amino acids, essential-, E500000000

Molecular Formula

C₅₂H₉₄N₁₀O₁₇S

Molecular Weight

1163.4 g/mol

InChI Key

CSARAUHTYFKILW-HGFMUWJKSA-N

Amino acids that are not synthesized by the human body in amounts sufficient to carry out physiological functions. They are obtained from dietary foodstuffs.

1 2D Structure

Amino Acids Mixture

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S,3R)-2-amino-3-hydroxybutanoic acid;(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid;(2S)-2-amino-3-methylbutanoic acid;(2S)-2-amino-4-methylpentanoic acid;(2S,3S)-2-amino-3-methylpentanoic acid;(2S)-2-amino-4-methylsulfanylbutanoic acid;(2S)-2-amino-3-phenylpropanoic acid;(2S)-2,6-diaminohexanoic acid

2.1.2 InChI

InChI=1S/C11H12N2O2.C9H11NO2.C6H14N2O2.2C6H13NO2.C5H11NO2S.C5H11NO2.C4H9NO3/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10;10-8(9(11)12)6-7-4-2-1-3-5-7;7-4-2-1-3-5(8)6(9)10;1-4(2)3-5(7)6(8)9;1-3-4(2)5(7)6(8)9;1-9-3-2-4(6)5(7)8;1-3(2)4(6)5(7)8;1-2(6)3(5)4(7)8/h1-4,6,9,13H,5,12H2,(H,14,15);1-5,8H,6,10H2,(H,11,12);5H,1-4,7-8H2,(H,9,10);2*4-5H,3,7H2,1-2H3,(H,8,9);4H,2-3,6H2,1H3,(H,7,8);3-4H,6H2,1-2H3,(H,7,8);2-3,6H,5H2,1H3,(H,7,8)/t9-;8-;2*5-;4-,5-;2*4-;2-,3+/m00000001/s1

2.1.3 InChI Key

CSARAUHTYFKILW-HGFMUWJKSA-N

2.1.4 Canonical SMILES

CCC(C)C(C(=O)O)N.CC(C)CC(C(=O)O)N.CC(C)C(C(=O)O)N.CC(C(C(=O)O)N)O.CSCCC(C(=O)O)N.C1=CC=C(C=C1)CC(C(=O)O)N.C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)N.C(CCN)CC(C(=O)O)N

2.1.5 Isomeric SMILES

CC[C@H](C)[C@@H](C(=O)O)N.C[C@H]([C@@H](C(=O)O)N)O.CC(C)C[C@@H](C(=O)O)N.CC(C)[C@@H](C(=O)O)N.CSCC[C@@H](C(=O)O)N.C1=CC=C(C=C1)C[C@@H](C(=O)O)N.C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)O)N.C(CCN)C[C@@H](C(=O)O)N

2.2 Synonyms

2.2.1 MeSH Synonyms

1. Acid, Essential Amino

2. Acids, Essential Amino

3. Amino Acid, Essential

4. Amino Acids, Essential

5. Essential Amino Acid

2.2.2 Depositor-Supplied Synonyms

1. Amino Acids, Essential

2. Amino Acids, Essential-

3. E500000000

2.3 Create Date

2012-03-21

3 Chemical and Physical Properties

Molecular Formula	C₅₂H₉₄N₁₀O₁₇S
Molecular Weight	1163.4 g/mol
Hydrogen Bond Donor Count	19
Hydrogen Bond Acceptor Count	27
Rotatable Bond Count	25
Exact Mass	1162.65191274 g/mol
Monoisotopic Mass	1162.65191274 g/mol
Topological Polar Surface Area	594 Å²
Heavy Atom Count	80
Formal Charge	0
Complexity	988
Isotope Atom Count	0
Defined Atom Stereocenter Count	10
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	8

API SUPPLIERS

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USDMF

01

Ajinomoto Co Inc

Japan

Discovery on Target

Not Confirmed

02

Kyowa Hakko Bio Co Ltd

Japan

Japan

Discovery on Target

Not Confirmed

Not Confirmed

Only 10 entries up to this point, click to access all

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CEP/COS

01

Ajinomoto Co., Inc. Tokyo JP

Japan

Discovery on Target

Not Confirmed

Japan

Discovery on Target

Not Confirmed

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Drugs in Development

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INTERMEDIATES SUPPLIERS

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FDF Dossiers

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FDA Orange Book

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Europe

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South Africa

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Listed Dossiers

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DRUG PRODUCT COMPOSITIONS

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DOSAGE - INJECTABLE;INJECTION - 10% (10GM/100...DOSAGE - INJECTABLE;INJECTION - 10% (10GM/100ML)

USFDA APPLICATION NUMBER - 19018

DOSAGE - INJECTABLE;INJECTION - 6% (6GM/100ML...DOSAGE - INJECTABLE;INJECTION - 6% (6GM/100ML)

USFDA APPLICATION NUMBER - 19018

DOSAGE - EMULSION;INTRAVENOUS - 2.4%;20MG/100...DOSAGE - EMULSION;INTRAVENOUS - 2.4%;20MG/100ML;6.8GM/100ML;68MG/100ML;124MG/100ML;170MG/100ML;105MG/100ML;3.5GM/100ML (1440ML)