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Chemistry

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Also known as: Pteramina, 4-aminopteroylglutamic acid, 4-aminofolic acid; apga, 2-(4-((2,4-diaminopteridin-6-yl)methylamino)-benzamido)pentanedioic acid, 4-amino-4-deoxypteroylglutamate, Folic acid, 4-amino-
Molecular Formula
C19H20N8O5
Molecular Weight
440.4  g/mol
InChI Key
TVZGACDUOSZQKY-UHFFFAOYSA-N

Aminopterin
1 2D Structure

Aminopterin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
2.1.2 InChI
InChI=1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)
2.1.3 InChI Key
TVZGACDUOSZQKY-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1C(=O)NC(CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N
2.2 Synonyms
2.2.1 Depositor-Supplied Synonyms

1. Pteramina

2. 4-aminopteroylglutamic Acid

3. 4-aminofolic Acid; Apga

4. 2-(4-((2,4-diaminopteridin-6-yl)methylamino)-benzamido)pentanedioic Acid

5. 4-amino-4-deoxypteroylglutamate

6. Folic Acid, 4-amino-

7. N-[(4-{[(2,4-diaminopteridin-6-yl)methyl]amino}phenyl)carbonyl]glutamic Acid

8. 1236566-87-2

9. N-[4-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]glutamic Acid

10. 4-aminopteroyl-glutamic Acid

11. Aminofolic Acid, 4-

12. Sr-01000075636

13. Nsc739

14. 4-aminofolate

15. Ncgc00015038-03

16. 4-aminopteroylglutamate

17. Spectrum_001874

18. Specplus_000899

19. Spectrum2_000893

20. Spectrum3_001386

21. Spectrum4_000917

22. Spectrum5_000931

23. A 1784

24. Schembl8887

25. Lopac0_000034

26. Bspbio_002972

27. Kbiogr_001414

28. Kbioss_002396

29. Mls002153337

30. Divk1c_006995

31. Spectrum1500679

32. Spbio_000706

33. Chembl274619

34. Schembl8161477

35. Kbio1_001939

36. Kbio2_002391

37. Kbio2_004959

38. Kbio2_007527

39. Kbio3_002192

40. Dtxsid10858993

41. Hms1921c08

42. Hms3260g09

43. Pharmakon1600-01500679

44. Tox21_500034

45. Ccg-39745

46. Nsc757427

47. Stl477234

48. Akos015854984

49. Lp00034

50. Nsc-757427

51. Sb17355

52. Sdccgsbi-0050023.p004

53. Ncgc00015038-02

54. Ncgc00015038-04

55. Ncgc00015038-05

56. Ncgc00015038-06

57. Ncgc00015038-07

58. Ncgc00015038-08

59. Ncgc00015038-09

60. Ncgc00015038-10

61. Ncgc00015038-12

62. Ncgc00093553-01

63. Ncgc00093553-02

64. Ncgc00093553-03

65. Ncgc00093553-04

66. Ncgc00093553-05

67. Ncgc00093553-06

68. Ncgc00260719-01

69. As-75721

70. Smr001230749

71. Sbi-0050023.p003

72. Db-052619

73. Eu-0100034

74. Ft-0622297

75. Ab00053283_04

76. Sr-01000075636-1

77. Sr-01000075636-5

78. Wln: T66 Bn Dn Gn Jnj Cz Ez H1mr Dvmyvq2vq

79. L-glutamic Acid,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-,

80. Glutamic Acid,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-, L-

81. 2-(4-(((2,4-diaminopteridin-6-yl)methyl)amino)benzamido)pentanedioicacid

82. L-n-[p-[[(2,4-diamino-6-pteridinyl)methyl]amino]benzoyl]-glutamic Acid

83. 2-[[4-[[(2,4-diaminopteridine-6-yl)methyl]amino]benzoyl]amino]pentanedioic Acid

2.3 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 440.4 g/mol
Molecular Formula C19H20N8O5
XLogP3-2
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count12
Rotatable Bond Count9
Exact Mass440.15566577 g/mol
Monoisotopic Mass440.15566577 g/mol
Topological Polar Surface Area219 Ų
Heavy Atom Count32
Formal Charge0
Complexity674
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Aminopterin Manufacturers

A Aminopterin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Aminopterin, including repackagers and relabelers. The FDA regulates Aminopterin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Aminopterin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Aminopterin Suppliers

A Aminopterin supplier is an individual or a company that provides Aminopterin active pharmaceutical ingredient (API) or Aminopterin finished formulations upon request. The Aminopterin suppliers may include Aminopterin API manufacturers, exporters, distributors and traders.

Aminopterin GMP

Aminopterin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Aminopterin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Aminopterin GMP manufacturer or Aminopterin GMP API supplier for your needs.

Aminopterin CoA

A Aminopterin CoA (Certificate of Analysis) is a formal document that attests to Aminopterin's compliance with Aminopterin specifications and serves as a tool for batch-level quality control.

Aminopterin CoA mostly includes findings from lab analyses of a specific batch. For each Aminopterin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Aminopterin may be tested according to a variety of international standards, such as European Pharmacopoeia (Aminopterin EP), Aminopterin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Aminopterin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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