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Also known as: 246852-12-0, 3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate methanesulfonate, Amlodipine mesilate, 291y33ezha, 246852-12-0 (mesylate), 3,5-pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester methanesulfonate (1:1)
Molecular Formula
C21H29ClN2O8S
Molecular Weight
505.0  g/mol
InChI Key
MUVFCHUBATVFPP-UHFFFAOYSA-N
FDA UNII
291Y33EZHA

Amlodipine Mesylate
1 2D Structure

Amlodipine Mesylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;methanesulfonic acid
2.1.2 InChI
InChI=1S/C20H25ClN2O5.CH4O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;1-5(2,3)4/h5-8,17,23H,4,9-11,22H2,1-3H3;1H3,(H,2,3,4)
2.1.3 InChI Key
MUVFCHUBATVFPP-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.CS(=O)(=O)O
2.2 Other Identifiers
2.2.1 UNII
291Y33EZHA
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 246852-12-0

2. 3-ethyl 5-methyl 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Methanesulfonate

3. Amlodipine Mesilate

4. 291y33ezha

5. 246852-12-0 (mesylate)

6. 3,5-pyridinedicarboxylic Acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl Ester Methanesulfonate (1:1)

7. 3-o-ethyl 5-o-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate;methanesulfonic Acid

8. 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; Methanesulfonic Acid

9. Unii-291y33ezha

10. Amlodipine (mesylate)

11. Schembl1164621

12. Amlodipine (as Mesilate)

13. Hy-b0317c

14. Amy7135

15. Bcp11874

16. Wja85212

17. Amlodipine Mesilate [who-dd]

18. As-75125

19. D93316

20. Q27254365

21. 3-ethyl5-methyl2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylatemethanesulfonate

2.3.2 Other Synonyms

1. Amilostad

2. Amlodipine Mesylate Monohydrate

3. Amlodipine Mesilate Monohydrate

4. Cardilopina

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 505.0 g/mol
Molecular Formula C21H29ClN2O8S
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count10
Rotatable Bond Count10
Exact Mass504.1333148 g/mol
Monoisotopic Mass504.1333148 g/mol
Topological Polar Surface Area163 Ų
Heavy Atom Count33
Formal Charge0
Complexity739
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2

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