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Chemistry

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Also known as: 631-61-8, Acetic acid, ammonium salt, Ammoniumacetate, Azanium;acetate, Acetic acid ammonium salt, Ammonium ethanoate
Molecular Formula
C2H7NO2
Molecular Weight
77.08  g/mol
InChI Key
USFZMSVCRYTOJT-UHFFFAOYSA-N
FDA UNII
RRE756S6Q2

Ammonium Acetate
1 2D Structure

Ammonium Acetate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
azanium;acetate
2.1.2 InChI
InChI=1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3
2.1.3 InChI Key
USFZMSVCRYTOJT-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(=O)[O-].[NH4+]
2.2 Other Identifiers
2.2.1 UNII
RRE756S6Q2
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 631-61-8

2. Acetic Acid, Ammonium Salt

3. Ammoniumacetate

4. Azanium;acetate

5. Acetic Acid Ammonium Salt

6. Ammonium Ethanoate

7. Aconh4

8. Ch3coonh4

9. Ch3co2nh4

10. Rre756s6q2

11. Ammonia Acetate

12. Mfcd00013066

13. Azanium Acetate

14. Amoniumacetate

15. Unii-rre756s6q2

16. Ammonium-acetate

17. Hsdb 556

18. Acetic Acid Amine

19. Ammonium Acetate-

20. Ammonia Acetate Salt

21. Einecs 211-162-9

22. Acetic Acid Ammoniate

23. Ammonium Acetate Acs

24. Nh4oac

25. Ammonium Aceticum

26. Ai3-26540

27. Ec 211-162-9

28. Ammonium Acetate [ii]

29. Ammonium Acetate [mi]

30. Ammonium Acetate Solution, 5m

31. Ins No. 264

32. Ammonium Acetate [hsdb]

33. Ammonium Acetate [inci]

34. Ammonium Aceticum [hpus]

35. Dtxsid5023873

36. Chebi:62947

37. Ammonium Acetate [mart.]

38. Ammonium Acetate [who-dd]

39. Ammonium Acetate, Biochemical Grade

40. Acetic Acid, Ammonium Salt (1:1)

41. Akos015904610

42. Ammonium Acetate, 5m Aqueous Solution

43. E264

44. E 264

45. E-264

46. Ft-0622306

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 77.08 g/mol
Molecular Formula C2H7NO2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass77.047678466 g/mol
Monoisotopic Mass77.047678466 g/mol
Topological Polar Surface Area41.1 Ų
Heavy Atom Count5
Formal Charge0
Complexity25.5
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Therapeutic Uses

Diuretic

Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 82


MEDICATION (VET): AS NUTRIENT

Rossoff, I.S. Handbook of Veterinary Drugs. New York: Springer Publishing Company, 1974., p. 15


MEDICATION (VET): Formerly a diuretic, antipyretic

Budavari, S. (ed.). The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals. Rahway, NJ: Merck and Co., Inc., 1989., p. 82


5 Pharmacology and Biochemistry
5.1 Mechanism of Action

ALTHOUGH PRECISE MECHANISM OF SYSTEMIC AMMONIA INTOXICATION REMAINS TO BE ELUCIDATED, EVIDENCE EXISTS TO SUGGEST THAT AN INTERFERENCE WITH CEREBRAL OXIDATIVE ENERGY METABOLISM IS INVOLVED. IN RATS MADE COMATOSE WITH AMMONIUM ACETATE, SAMPLES OF BASILAR BRAIN STRUCTURES SHOWED SIGNIFICANT DECR IN GLYCOGEN, GLUCOSE, ATP, & ESPECIALLY IN PHOSPHOCREATINE.

Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. III-23


The effects of ammonium ions on the release of glutamic acid from the rat cerebral cortex were measured in vivo using cortical cups & multiple ion detection technique. The results indicate that ammonium ions increase the release & the formation of glutamic acid in the brain. The resulting increased concn of this amino acid in extracellular spaces may be one of the mechanisms of ammonia toxicity in vivo. /Ammonium ions/

PMID:6131108 Moroni F et al; J Neurochem 40 (3): 850-4 (1983)


API Reference Price

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08-Jan-2021
27-Nov-2024
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ABOUT THIS PAGE

Ammonium Acetate Manufacturers

A Ammonium Acetate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ammonium Acetate, including repackagers and relabelers. The FDA regulates Ammonium Acetate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ammonium Acetate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ammonium Acetate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ammonium Acetate Suppliers

A Ammonium Acetate supplier is an individual or a company that provides Ammonium Acetate active pharmaceutical ingredient (API) or Ammonium Acetate finished formulations upon request. The Ammonium Acetate suppliers may include Ammonium Acetate API manufacturers, exporters, distributors and traders.

click here to find a list of Ammonium Acetate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ammonium Acetate USDMF

A Ammonium Acetate DMF (Drug Master File) is a document detailing the whole manufacturing process of Ammonium Acetate active pharmaceutical ingredient (API) in detail. Different forms of Ammonium Acetate DMFs exist exist since differing nations have different regulations, such as Ammonium Acetate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Ammonium Acetate DMF submitted to regulatory agencies in the US is known as a USDMF. Ammonium Acetate USDMF includes data on Ammonium Acetate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ammonium Acetate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Ammonium Acetate suppliers with USDMF on PharmaCompass.

Ammonium Acetate GMP

Ammonium Acetate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ammonium Acetate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ammonium Acetate GMP manufacturer or Ammonium Acetate GMP API supplier for your needs.

Ammonium Acetate CoA

A Ammonium Acetate CoA (Certificate of Analysis) is a formal document that attests to Ammonium Acetate's compliance with Ammonium Acetate specifications and serves as a tool for batch-level quality control.

Ammonium Acetate CoA mostly includes findings from lab analyses of a specific batch. For each Ammonium Acetate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ammonium Acetate may be tested according to a variety of international standards, such as European Pharmacopoeia (Ammonium Acetate EP), Ammonium Acetate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ammonium Acetate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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