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Also known as: Ammonium glycyrrhizinate, 53956-04-0, 1407-03-0, Monoammonium glycyrrhizinate, Glycamil, Glycyrram
Molecular Formula
C42H65NO16
Molecular Weight
840.0  g/mol
InChI Key
ILRKKHJEINIICQ-OOFFSTKBSA-N
FDA UNII
3VRD35U26C

Ammonium Glycyrrhizinate
An oleanolic acid from GLYCYRRHIZA that has some antiallergic, antibacterial, and antiviral properties. It is used topically for allergic or infectious skin inflammation and orally for its aldosterone effects in electrolyte regulation.
1 2D Structure

Ammonium Glycyrrhizinate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3S,4S,5R,6R)-6-[(2S,3R,4S,5S,6S)-2-[[(3S,4aR,6aR,6bS,8aS,11S,12aR,14aR,14bS)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1H-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid;azane
2.1.2 InChI
InChI=1S/C42H62O16.H3N/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50;/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54);1H3/t19-,21-,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+;/m0./s1
2.1.3 InChI Key
ILRKKHJEINIICQ-OOFFSTKBSA-N
2.1.4 Canonical SMILES
CC1(C2CCC3(C(C2(CCC1OC4C(C(C(C(O4)C(=O)O)O)O)OC5C(C(C(C(O5)C(=O)O)O)O)O)C)C(=O)C=C6C3(CCC7(C6CC(CC7)(C)C(=O)O)C)C)C)C.N
2.1.5 Isomeric SMILES
C[C@]12CC[C@](C[C@H]1C3=CC(=O)[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O[C@@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O)O[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)C(=O)O)O)O)O)C)(C)C(=O)O.N
2.2 Other Identifiers
2.2.1 UNII
3VRD35U26C
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 12, Po

2. Acid, Glycyrrhetic

3. Acid, Glycyrrhetinic

4. Acid, Rhetinic

5. Acid, Uralenic

6. Arthrodont

7. Enoxolone

8. Glyciram

9. Glycyram

10. Glycyrrhetic Acid

11. Glycyrrhetinic Acid

12. Jintan

13. Po 12

14. Rhetinic Acid

15. Uralenic Acid

2.3.2 Depositor-Supplied Synonyms

1. Ammonium Glycyrrhizinate

2. 53956-04-0

3. 1407-03-0

4. Monoammonium Glycyrrhizinate

5. Glycamil

6. Glycyrram

7. Monoammonium Glycyrrhizate

8. Amgz

9. Ammoniated Glycyrrhizin

10. Glycyrrhizic Acid Ammonium Salt

11. Glycyrrhizic Acid, Monoammonium Salt

12. Glycyrrhizinic Acid, Ammonium Salt (1:1)

13. Glycyrrhizic Acid, Ammonium Salt

14. Glycyrrhizin, Ammoniated

15. 3vrd35u26c

16. Nsc 2800

17. Ammonium Glycyrrhizinate (amgz)

18. Glycyram

19. (2s,3s,4s,5r,6r)-6-[(2s,3r,4s,5s,6s)-2-[[(3s,4ar,6ar,6bs,8as,11s,12ar,14ar,14bs)-11-carboxy-4,4,6a,6b,8a,11,14b-heptamethyl-14-oxo-2,3,4a,5,6,7,8,9,10,12,12a,14a-dodecahydro-1h-picen-3-yl]oxy]-6-carboxy-4,5-dihydroxyoxan-3-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic Acid;azane

20. Monoammonium Glycyrrhizinate Hydrate

21. Monoammoniumglycyrrhizinate

22. .alpha.-d-glucopyranosiduronic Acid, (3.beta.,20.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-.beta.-d-glucopyranuronosyl-, Monoammonium Salt

23. Monoammonium Glycyrrhizinate (jan)

24. Monoammonium Glycyrrhizinate [jan]

25. Fema No. 2528

26. Ccris 1897

27. Einecs 258-887-7

28. Unii-3vrd35u26c

29. Magnasweet

30. Nsc-2800

31. Glycyrrhizin, Ammoniated (glycyrrhiza Spp.)

32. Nsc-35348

33. Amgz;glycyram

34. Mfcd00167400

35. Glycyrrhizin Ammoniacal

36. Glycyron No.1 (tn)

37. Ammonium Glycyrrhizate (nf)

38. Alpha-d-glucopyranosiduronic Acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-beta-d-glucopyranuronosyl-,

39. Monoammonium (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-beta-d-glucopyranuronosyl-alpha-d-glucopyranosidu

40. Schembl152097

41. Glycyrrhizin Acid Ammonium Salt

42. Chebi:81864

43. Hy-n0184b

44. Monoammonium 18

45. A-glycyrrhizinate

46. Ammonium Glycyrrhizate [ii]

47. Cs-m0783

48. Ammonium Glycyrrhizate [inci]

49. S2376

50. S9143

51. Akos022168214

52. Ammonium Glycyrrhizate [usp-rs]

53. Ccg-270522

54. Ccg-270523

55. Alpha-d-glucopyranosiduronic Acid, (3-beta,20-beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-beta-d-glucopyranuronosyl-, Ammoniate

56. Alpha-d-glucopyranosiduronic Acid, (3beta,20beta)-20-carboxy-11-oxo-30-norlean-12-en-3-yl-2-o-beta-d- -glucopyranuronosyl-, Ammoniate

57. Alpha-d-glucopyranosiduronic Acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-beta-d-glucopyranuronosyl-, Monoammonium Salt

58. Ammonium Dihydrogen Glycyrrhizinate

59. Hy-76225

60. Ammonium Glycyrrhizate [ep Monograph]

61. Cs-0027757

62. N1944

63. C18610

64. D04987

65. Rdx013 Component Ammonium Glycyrrhizate

66. Rdx-013 Component Ammonium Glycyrrhizate

67. Ammonium Glycyrrhizate Component Of Rdx013

68. Glycyrrhizic Acid, Ammonium Salt [who-dd]

69. 53956-04-0 1407-03-0(base)

70. Ammonium Glycyrrhizate Component Of Rdx-013

71. Q-201173

72. Q27155631

73. Glycyrrhizic Acid Ammonium Salt, Analytical Standard, For Hplc

74. Ammonium Glycyrrhizate, European Pharmacopoeia (ep) Reference Standard

75. Ammonium Glycyrrhizate, United States Pharmacopeia (usp) Reference Standard

76. Glycyrrhizate Monoammonium, European Pharmacopoeia (ep) Reference Standard

77. Glycyrrhizic Acid Ammonium Salt, Primary Pharmaceutical Reference Standard

78. Ammonium Glycyrrhizate, Pharmaceutical Secondary Standard; Certified Reference Material

79. Glycyrrhizic Acid Ammonium Salt From Glycyrrhiza Root (licorice), >=70% (hplc)

80. Glycyrrhizic Acid Ammonium Salt From Glycyrrhiza Root (licorice), >=95.0% (nt)

81. .alpha.-d-glucopyranosiduronic Acid, (3-.beta.,20-.beta.)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-.beta.-d-glucopyranuronosyl-, Ammoniate

82. Alpha-d-glucopyranosiduronic Acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-o-beta-d-glucopyranuronosyl-, Ammonium Salt (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 840.0 g/mol
Molecular Formula C42H65NO16
Hydrogen Bond Donor Count9
Hydrogen Bond Acceptor Count17
Rotatable Bond Count7
Exact Mass839.43033499 g/mol
Monoisotopic Mass839.43033499 g/mol
Topological Polar Surface Area268 Ų
Heavy Atom Count59
Formal Charge0
Complexity1730
Isotope Atom Count0
Defined Atom Stereocenter Count19
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents

Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)


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29-Apr-2021
13-Dec-2024
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Looking for 53956-04-0 / Monoammonium Glycyrrhizinate API manufacturers, exporters & distributors?

Monoammonium Glycyrrhizinate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Monoammonium Glycyrrhizinate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Monoammonium Glycyrrhizinate manufacturer or Monoammonium Glycyrrhizinate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Monoammonium Glycyrrhizinate manufacturer or Monoammonium Glycyrrhizinate supplier.

PharmaCompass also assists you with knowing the Monoammonium Glycyrrhizinate API Price utilized in the formulation of products. Monoammonium Glycyrrhizinate API Price is not always fixed or binding as the Monoammonium Glycyrrhizinate Price is obtained through a variety of data sources. The Monoammonium Glycyrrhizinate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Monoammonium Glycyrrhizinate

Synonyms

Ammonium glycyrrhizinate, 53956-04-0, 1407-03-0, Glycamil, Glycyrram, Monoammonium glycyrrhizate

Cas Number

53956-04-0

Unique Ingredient Identifier (UNII)

3VRD35U26C

About Monoammonium Glycyrrhizinate

An oleanolic acid from GLYCYRRHIZA that has some antiallergic, antibacterial, and antiviral properties. It is used topically for allergic or infectious skin inflammation and orally for its aldosterone effects in electrolyte regulation.

Ammonium Glycyrrhizinate Manufacturers

A Ammonium Glycyrrhizinate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Ammonium Glycyrrhizinate, including repackagers and relabelers. The FDA regulates Ammonium Glycyrrhizinate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Ammonium Glycyrrhizinate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Ammonium Glycyrrhizinate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Ammonium Glycyrrhizinate Suppliers

A Ammonium Glycyrrhizinate supplier is an individual or a company that provides Ammonium Glycyrrhizinate active pharmaceutical ingredient (API) or Ammonium Glycyrrhizinate finished formulations upon request. The Ammonium Glycyrrhizinate suppliers may include Ammonium Glycyrrhizinate API manufacturers, exporters, distributors and traders.

click here to find a list of Ammonium Glycyrrhizinate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Ammonium Glycyrrhizinate USDMF

A Ammonium Glycyrrhizinate DMF (Drug Master File) is a document detailing the whole manufacturing process of Ammonium Glycyrrhizinate active pharmaceutical ingredient (API) in detail. Different forms of Ammonium Glycyrrhizinate DMFs exist exist since differing nations have different regulations, such as Ammonium Glycyrrhizinate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Ammonium Glycyrrhizinate DMF submitted to regulatory agencies in the US is known as a USDMF. Ammonium Glycyrrhizinate USDMF includes data on Ammonium Glycyrrhizinate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Ammonium Glycyrrhizinate USDMF is kept confidential to protect the manufacturer’s intellectual property.

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Ammonium Glycyrrhizinate JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Ammonium Glycyrrhizinate Drug Master File in Japan (Ammonium Glycyrrhizinate JDMF) empowers Ammonium Glycyrrhizinate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Ammonium Glycyrrhizinate JDMF during the approval evaluation for pharmaceutical products. At the time of Ammonium Glycyrrhizinate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Ammonium Glycyrrhizinate suppliers with JDMF on PharmaCompass.

Ammonium Glycyrrhizinate CEP

A Ammonium Glycyrrhizinate CEP of the European Pharmacopoeia monograph is often referred to as a Ammonium Glycyrrhizinate Certificate of Suitability (COS). The purpose of a Ammonium Glycyrrhizinate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Ammonium Glycyrrhizinate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Ammonium Glycyrrhizinate to their clients by showing that a Ammonium Glycyrrhizinate CEP has been issued for it. The manufacturer submits a Ammonium Glycyrrhizinate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Ammonium Glycyrrhizinate CEP holder for the record. Additionally, the data presented in the Ammonium Glycyrrhizinate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Ammonium Glycyrrhizinate DMF.

A Ammonium Glycyrrhizinate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Ammonium Glycyrrhizinate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

click here to find a list of Ammonium Glycyrrhizinate suppliers with CEP (COS) on PharmaCompass.

Ammonium Glycyrrhizinate GMP

Ammonium Glycyrrhizinate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Ammonium Glycyrrhizinate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Ammonium Glycyrrhizinate GMP manufacturer or Ammonium Glycyrrhizinate GMP API supplier for your needs.

Ammonium Glycyrrhizinate CoA

A Ammonium Glycyrrhizinate CoA (Certificate of Analysis) is a formal document that attests to Ammonium Glycyrrhizinate's compliance with Ammonium Glycyrrhizinate specifications and serves as a tool for batch-level quality control.

Ammonium Glycyrrhizinate CoA mostly includes findings from lab analyses of a specific batch. For each Ammonium Glycyrrhizinate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Ammonium Glycyrrhizinate may be tested according to a variety of international standards, such as European Pharmacopoeia (Ammonium Glycyrrhizinate EP), Ammonium Glycyrrhizinate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Ammonium Glycyrrhizinate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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