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Amodiaquin Dihydrochloride Dihydrate

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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ACTIVE PHARMA INGREDIENTS

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Synopsis

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Chemistry

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Also known as: 6398-98-7, Amodiaquine hcl, Amodiaquine hydrochloride, Amodiaquine dihydrochloride dihydrate, 4-((7-chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenol dihydrochloride dihydrate, Amodiaquin hcl hydrate

Molecular Formula

C₂₀H₂₈Cl₃N₃O₃

Molecular Weight

464.8 g/mol

InChI Key

YVNAYSHNIILOJS-UHFFFAOYSA-N

FDA UNII

K6PW2S574L

A 4-aminoquinoline compound with anti-inflammatory properties.

1 2D Structure

Amodiaquin Dihydrochloride Dihydrate

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol;dihydrate;dihydrochloride

2.1.2 InChI

InChI=1S/C20H22ClN3O.2ClH.2H2O/c1-3-24(4-2)13-14-11-16(6-8-20(14)25)23-18-9-10-22-19-12-15(21)5-7-17(18)19;;;;/h5-12,25H,3-4,13H2,1-2H3,(H,22,23);2*1H;2*1H2

2.1.3 InChI Key

YVNAYSHNIILOJS-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCN(CC)CC1=C(C=CC(=C1)NC2=C3C=CC(=CC3=NC=C2)Cl)O.O.O.Cl.Cl

2.2 Other Identifiers

2.2.1 UNII

K6PW2S574L

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Amodiachin

2. Amodiaquin

3. Amodiaquine

4. Amodiaquine Hydrochloride

5. Camoquin

6. Camoquine

7. Flavoquine

8. Hydrochloride, Amodiaquine

2.3.2 Depositor-Supplied Synonyms

1. 6398-98-7

2. Amodiaquine Hcl

3. Amodiaquine Hydrochloride

4. Amodiaquine Dihydrochloride Dihydrate

5. 4-((7-chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenol Dihydrochloride Dihydrate

6. Amodiaquin Hcl Hydrate

7. K6pw2s574l

8. Amodiaquine Hydrochloride [usp]

9. 6398-98-7 (hcl Hydrate)

10. Amodiaquine (dihydrochloride Dihydrate)

11. Nsc-755863

12. Ncgc00017063-01

13. Cas-6398-98-7

14. 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol Dihydrate Dihydrochloride

15. 4-[(7-chloroquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol;dihydrate;dihydrochloride

16. Amodiaquine Hydrochloride (usp)

17. Camoquin Hydrochloride

18. Chebi:50652

19. Phenol, 4-((7-chloro-4-quinolinyl)amino)-2-((diethylamino)methyl)-, Dihydrochloride, Dihydrate

20. Cam-aq 1

21. Unii-k6pw2s574l

22. Amodiaquin Dihydrochlorid-2-wasser

23. Prestwick_677

24. Sn 10751

25. Amodiaquini Hydrochloridum

26. Amodiaquin Dihcl Dihydrate

27. Camoquin Hydrochloride (tn)

28. Dsstox_cid_25568

29. Dsstox_rid_80965

30. Dsstox_gsid_45568

31. Amodiaquindihydrochloridedihydrate

32. Chembl1357648

33. Dtxsid3045568

34. S4589 Amodiaquin (dihydrochlori

35. Hms1568n20

36. Hy-b1322

37. Tox21_110765

38. Mfcd09260307

39. S4589

40. Akos016339633

41. Ccg-220309

42. Cs-4895

43. Ks-1326

44. Ks-5250

45. Nsc 755863

46. 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-o-cresol Dihydrochloride Dihydrate

47. 4-(7-chloro-4-quinolinylamino)-2-(diethylaminomethyl)phenol Dihydrochloride Dihydrate

48. Amodiaquine Hydrochloride [mart.]

49. Amodiaquine Hydrochloride [vandf]

50. Ncgc00017063-02

51. Ncgc00017063-03

52. Amodiaquine Hydrochloride [usp-rs]

53. Amodiaquine Hydrochloride [who-dd]

54. Amodiaquine Hydrochloride [who-ip]

55. Db-054591

56. Ft-0740309

57. A16405

58. Amodiaquine Hydrochloride [orange Book]

59. D02466

60. D95328

61. Amodiaquine Hydrochloride [usp Monograph]

62. Amodiaquini Hydrochloridum [who-ip Latin]

63. A834604

64. Amodiaquine Dihydrochloride Dihydrate [mi]

65. Amodiaquine Hydrochloride Dihydrate [who-dd]

66. Q27122169

67. Z1563146060

68. 4-[(7-chloranylquinolin-4-yl)amino]-2-(diethylaminomethyl)phenol Dihydrate Dihydrochloride

69. 4-[(7-chloro-4-quinolinyl)amino]-2-(diethylaminomethyl)phenol Dihydrate Dihydrochloride

70. O-cresol, 4-((7-chloro-4-quinolyl)amino)-alpha-(diethylamino)-, Dihydrochloride, Dihydrate

71. 4-((7-chloro-4-quinolyl)amino)-.alpha.-(diethylamino)-o-cresol Dihydrochloride Dihydrate

2.4 Create Date

2005-08-08

3 Chemical and Physical Properties

Molecular Formula	C₂₀H₂₈Cl₃N₃O₃
Molecular Weight	464.8 g/mol
Hydrogen Bond Donor Count	6
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	6
Exact Mass	463.119625 g/mol
Monoisotopic Mass	463.119625 g/mol
Topological Polar Surface Area	50.4 Å²
Heavy Atom Count	29
Formal Charge	0
Complexity	406
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	5

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antimalarials

Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585) (See all compounds classified as Antimalarials.)

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ABOUT THIS PAGE

Amodiaquin Dihydrochloride Dihydrate Manufacturers

A Amodiaquin Dihydrochloride Dihydrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Amodiaquin Dihydrochloride Dihydrate, including repackagers and relabelers. The FDA regulates Amodiaquin Dihydrochloride Dihydrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Amodiaquin Dihydrochloride Dihydrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Amodiaquin Dihydrochloride Dihydrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Amodiaquin Dihydrochloride Dihydrate Suppliers

A Amodiaquin Dihydrochloride Dihydrate supplier is an individual or a company that provides Amodiaquin Dihydrochloride Dihydrate active pharmaceutical ingredient (API) or Amodiaquin Dihydrochloride Dihydrate finished formulations upon request. The Amodiaquin Dihydrochloride Dihydrate suppliers may include Amodiaquin Dihydrochloride Dihydrate API manufacturers, exporters, distributors and traders.

click here to find a list of Amodiaquin Dihydrochloride Dihydrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Amodiaquin Dihydrochloride Dihydrate GMP

Amodiaquin Dihydrochloride Dihydrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Amodiaquin Dihydrochloride Dihydrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Amodiaquin Dihydrochloride Dihydrate GMP manufacturer or Amodiaquin Dihydrochloride Dihydrate GMP API supplier for your needs.

Amodiaquin Dihydrochloride Dihydrate CoA

A Amodiaquin Dihydrochloride Dihydrate CoA (Certificate of Analysis) is a formal document that attests to Amodiaquin Dihydrochloride Dihydrate's compliance with Amodiaquin Dihydrochloride Dihydrate specifications and serves as a tool for batch-level quality control.

Amodiaquin Dihydrochloride Dihydrate CoA mostly includes findings from lab analyses of a specific batch. For each Amodiaquin Dihydrochloride Dihydrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Amodiaquin Dihydrochloride Dihydrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Amodiaquin Dihydrochloride Dihydrate EP), Amodiaquin Dihydrochloride Dihydrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Amodiaquin Dihydrochloride Dihydrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.