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Chemistry

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Also known as: 87344-06-7, 2-methoxyphenyl 2-(2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetamido)acetate, Artromed, Amtolmetin guacyl, St 679, St-679
Molecular Formula
C24H24N2O5
Molecular Weight
420.5  g/mol
InChI Key
CWJNMKKMGIAGDK-UHFFFAOYSA-N
FDA UNII
323A00CRO9

Amtolmetin Guacil
1 2D Structure

Amtolmetin Guacil

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2-methoxyphenyl) 2-[[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetyl]amino]acetate
2.1.2 InChI
InChI=1S/C24H24N2O5/c1-16-8-10-17(11-9-16)24(29)19-13-12-18(26(19)2)14-22(27)25-15-23(28)31-21-7-5-4-6-20(21)30-3/h4-13H,14-15H2,1-3H3,(H,25,27)
2.1.3 InChI Key
CWJNMKKMGIAGDK-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC=C(C=C1)C(=O)C2=CC=C(N2C)CC(=O)NCC(=O)OC3=CC=CC=C3OC
2.2 Other Identifiers
2.2.1 UNII
323A00CRO9
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-methoxyphenyl 1-methyl-5-(4-methylbenzoylpyrrol)-2-acetamidoacetate

2. Amtolmetin Guacyl

3. Amtolmetineguacil

4. Artromed

5. Med 15

6. Med-15

7. Med15

8. St 679

9. St-679

2.3.2 Depositor-Supplied Synonyms

1. 87344-06-7

2. 2-methoxyphenyl 2-(2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetamido)acetate

3. Artromed

4. Amtolmetin Guacyl

5. St 679

6. St-679

7. Med 15

8. Amtolmetin Guacil [inn]

9. Med-15

10. Finrid

11. Med15

12. 104076-16-6

13. 2-methoxyphenyl 1-methyl-5-p-methylbenzoylpyrrole-2-acetoamidoacetate

14. 323a00cro9

15. (2-methoxyphenyl) 2-[[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetyl]amino]acetate

16. Amtolmetin Guacil (inn)

17. N-((1-methyl-5-p-toluoylpyrrol-2-yl)acetyl)glycine O-methoxyphenyl Ester

18. 2-methoxyphenyl (2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetyl)glycinate

19. Eufans

20. Amtolmetine Guacil

21. Amtolmetina Guacilo

22. Amtolmetinum Guacilum

23. Amtolmetine Guacil [inn-french]

24. Amtolmetina Guacilo [inn-spanish]

25. Amtolmetinum Guacilum [inn-latin]

26. Unii-323a00cro9

27. Amtolmetin-guacil

28. Artromed (tn)

29. N-((1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetyl)glycine 2-methoxyphenyl Ester

30. Schembl24555

31. Mls006010220

32. Amtolmetin Guacil [mi]

33. Chembl1766570

34. Dtxsid50236291

35. Amtolmetin Guacil [mart.]

36. Chebi:135678

37. St679

38. Zinc596929

39. Amtolmetin Guacil [who-dd]

40. Bcp28767

41. Mfcd00866153

42. Stl451031

43. Akos015895070

44. Glycine, N-((1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl)acetyl)-, 2-methoxyphenyl Ester

45. Glycine, N-((5-benzoyl-1-methyl-1h-pyrrol-2-yl)acetyl)-, 2-methoxyphenyl Ester

46. N-[2-[1-methyl-5-(4-methylbenzoyl)-1h-pyrrol-2-yl]acetyl]glycine 2-methoxyphenyl Ester

47. As-30751

48. Smr004701308

49. Hy-107320

50. Cs-0028135

51. Ft-0659812

52. D07453

53. 344a067

54. A842102

55. Sr-01000945065

56. Q4748890

57. Sr-01000945065-1

58. (2-methoxyphenyl)2-[[2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetyl]amino] Acetate

59. 2-methoxyphenyl 2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrole-2-acetylamino)acetate

60. 2-methoxyphenyl 2-{2-[1-methyl-5-(4-methylbenzoyl)pyrrol-2-yl]acetamido}acetate

61. 2-methoxyphenyl N-({1-methyl-5-[(4-methylphenyl)carbonyl]-1h-pyrrol-2-yl}acetyl)glycinate

62. 2-methoxyphenyl2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrole-2-acetylamino)acetate

63. (2-methoxyphenyl) 2-[2-[1-methyl-5-(4-methylphenyl)carbonyl-pyrrol-2-yl]ethanoylamino]ethanoate

64. 2-[[2-[1-methyl-5-[(4-methylphenyl)-oxomethyl]-2-pyrrolyl]-1-oxoethyl]amino]acetic Acid (2-methoxyphenyl) Ester

65. Amtolmetin Guacil; 2-methoxyphenyl 2-(1-methyl-5-(4-methylbenzoyl)-1h-pyrrole-2-acetylamino)acetate

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 420.5 g/mol
Molecular Formula C24H24N2O5
XLogP34
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count9
Exact Mass420.16852187 g/mol
Monoisotopic Mass420.16852187 g/mol
Topological Polar Surface Area86.6 Ų
Heavy Atom Count31
Formal Charge0
Complexity632
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Inflammatory Agents, Non-Steroidal

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects. (See all compounds classified as Anti-Inflammatory Agents, Non-Steroidal.)


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Amtolmetin Guacil Manufacturers

A Amtolmetin Guacil manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Amtolmetin Guacil, including repackagers and relabelers. The FDA regulates Amtolmetin Guacil manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Amtolmetin Guacil API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Amtolmetin Guacil manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Amtolmetin Guacil Suppliers

A Amtolmetin Guacil supplier is an individual or a company that provides Amtolmetin Guacil active pharmaceutical ingredient (API) or Amtolmetin Guacil finished formulations upon request. The Amtolmetin Guacil suppliers may include Amtolmetin Guacil API manufacturers, exporters, distributors and traders.

click here to find a list of Amtolmetin Guacil suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Amtolmetin Guacil WC

A Amtolmetin Guacil written confirmation (Amtolmetin Guacil WC) is an official document issued by a regulatory agency to a Amtolmetin Guacil manufacturer, verifying that the manufacturing facility of a Amtolmetin Guacil active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Amtolmetin Guacil APIs or Amtolmetin Guacil finished pharmaceutical products to another nation, regulatory agencies frequently require a Amtolmetin Guacil WC (written confirmation) as part of the regulatory process.

click here to find a list of Amtolmetin Guacil suppliers with Written Confirmation (WC) on PharmaCompass.

Amtolmetin Guacil GMP

Amtolmetin Guacil Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Amtolmetin Guacil GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Amtolmetin Guacil GMP manufacturer or Amtolmetin Guacil GMP API supplier for your needs.

Amtolmetin Guacil CoA

A Amtolmetin Guacil CoA (Certificate of Analysis) is a formal document that attests to Amtolmetin Guacil's compliance with Amtolmetin Guacil specifications and serves as a tool for batch-level quality control.

Amtolmetin Guacil CoA mostly includes findings from lab analyses of a specific batch. For each Amtolmetin Guacil CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Amtolmetin Guacil may be tested according to a variety of international standards, such as European Pharmacopoeia (Amtolmetin Guacil EP), Amtolmetin Guacil JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Amtolmetin Guacil USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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