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    Chemistry

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    Also known as:
    Molecular Formula
    C10H8Cl3N3O
    Molecular Weight
    292.5  g/mol
    InChI Key
    TVWRQCIPWUCNMI-UHFFFAOYSA-N
    Anagrelide Hydrochloride
    1 2D Structure

    Anagrelide Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one;hydrochloride
    2.1.2 InChI
    InChI=1S/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;/h1-2H,3-4H2,(H,13,14,16);1H
    2.1.3 InChI Key
    TVWRQCIPWUCNMI-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl
    2.1.5 Isomeric SMILES
    C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl
    2.2 Create Date
    2005-03-26
    3 Chemical and Physical Properties
    Molecular Weight 292.5 g/mol
    Molecular Formula C10H8Cl3N3O
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count0
    Exact Mass290.973295 g/mol
    Monoisotopic Mass290.973295 g/mol
    Topological Polar Surface Area44.7 A^2
    Heavy Atom Count17
    Formal Charge0
    Complexity360
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 4  
    Drug NameAgrylin
    PubMed HealthAnagrelide (By mouth)
    Drug ClassesPlatelet Reducing Agent
    Drug LabelName: AGRYLIN (anagrelide hydrochloride)Dosage Form:0.5 mg capsules for oral administrationActive Ingredient:AGRYLIN Capsules contain 0.5 mg of anagrelide base (as anagrelide hydrochloride).Inactive Ingredients:Anhydrous Lactose NF, Crospov...
    Active IngredientAnagrelide hydrochloride
    Dosage FormCapsule
    RouteOral
    Strengtheq 0.5mg base
    Market StatusPrescription
    CompanyShire

    2 of 4  
    Drug NameAnagrelide hydrochloride
    Drug LabelAnagrelide hydrochloride is an off white powder that is very slightly soluble in water and sparingly soluble in dimethyl sulfoxide and in dimethylformamide. Anagrelide hydrochloride is a platelet-reducing agent with a chemical name of 6,7-dichloro-1,...
    Active IngredientAnagrelide hydrochloride
    Dosage FormCapsule
    RouteOral
    Strengtheq 0.5mg base; eq 1mg base
    Market StatusPrescription
    CompanyMylan Pharms; Ivax Sub Teva Pharms; Mylan; Impax Labs; Barr

    3 of 4  
    Drug NameAgrylin
    PubMed HealthAnagrelide (By mouth)
    Drug ClassesPlatelet Reducing Agent
    Drug LabelName: AGRYLIN (anagrelide hydrochloride)Dosage Form:0.5 mg capsules for oral administrationActive Ingredient:AGRYLIN Capsules contain 0.5 mg of anagrelide base (as anagrelide hydrochloride).Inactive Ingredients:Anhydrous Lactose NF, Crospov...
    Active IngredientAnagrelide hydrochloride
    Dosage FormCapsule
    RouteOral
    Strengtheq 0.5mg base
    Market StatusPrescription
    CompanyShire

    4 of 4  
    Drug NameAnagrelide hydrochloride
    Drug LabelAnagrelide hydrochloride is an off white powder that is very slightly soluble in water and sparingly soluble in dimethyl sulfoxide and in dimethylformamide. Anagrelide hydrochloride is a platelet-reducing agent with a chemical name of 6,7-dichloro-1,...
    Active IngredientAnagrelide hydrochloride
    Dosage FormCapsule
    RouteOral
    Strengtheq 0.5mg base; eq 1mg base
    Market StatusPrescription
    CompanyMylan Pharms; Ivax Sub Teva Pharms; Mylan; Impax Labs; Barr

    API Reference Price

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LIMITED","supplierCountry":"INDIA","foreign_port":"GUARULHOS","customer":"EMS","customerCountry":"BRAZIL","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"250000","totalValueFC":"248761.6","currency":"USD","unitRateINR":20675000,"date":"01-Jan-2024","totalValueINR":"20675000","totalValueInUsd":"248761.6","indian_port":"Bombay Air","hs_no":"29334900","bill_no":"6460229","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BRAZIL","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H, AHMEDABAD,GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709145000,"product":"ANAGRELIDE HYDROCHLORIDE USP, BATCH NO:FWP240024, MFG DATE:JAN2024, EXP DATE:DEC2028","address":"MUMBAI CENTRAL,","city":"MUMBAI, MAHARASHTRA.","supplier":"CIPLA","supplierCountry":"INDIA","foreign_port":"SEOUL - INCHEON INT\\'","customer":"PHARMBIO KOREA CO. ","customerCountry":"KOREA, REPUBLIC OF","quantity":"0.29","actualQuantity":"290","unit":"GMS","unitRateFc":"80.8","totalValueFC":"23033.5","currency":"USD","unitRateINR":6590.2703103448275,"date":"29-Feb-2024","totalValueINR":"1911178.39","totalValueInUsd":"23033.5","indian_port":"Bangalore Air","hs_no":"29335990","bill_no":"7945687","productDescription":"API","marketType":"REGULATED MARKET","country":"KOREA,REPUBLIC OF","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"MUMBAI CENTRAL,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1719858600,"product":"ANAGRELIDE HYDROCHLORIDE USP BATCH NO :FWP240167 MFG DATE : JUN2024 RETEST DATE: MAY2026","address":"MUMBAI CENTRAL,","city":"MUMBAI, MAHARASHTRA.","supplier":"CIPLA","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"PHARMADA ILAC SAN. ","customerCountry":"TURKEY","quantity":"0.46","actualQuantity":"457","unit":"GMS","unitRateFc":"80","totalValueFC":"35982.4","currency":"USD","unitRateINR":6581.6435010940922,"date":"02-Jul-2024","totalValueINR":"3007811.08","totalValueInUsd":"35982.4","indian_port":"Bangalore Air","hs_no":"29333990","bill_no":"2120288","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"MUMBAI CENTRAL,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1719426600,"product":"(UNDELIVERED & RETURNED) ANAGRELIDE HCI","address":"65 VETRI GARDEN NSK VAISHNAVI,SCHO","city":"SALEM,TAMIL NADU","supplier":"CHARTWELL NJ","supplierCountry":"INDIA","foreign_port":"NEW YORK","customer":"GLOBESYNTH PHARMA TECH","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.002","unit":"KGS","unitRateFc":"20000","totalValueFC":"49","currency":"USD","unitRateINR":"2043535","date":"27-Jun-2024","totalValueINR":"4087.07","totalValueInUsd":"49","indian_port":"Bangalore Air","hs_no":"29309099","bill_no":"4217937","productDescription":"Re-Import","marketType":"REGULATED MARKET","country":"INDIA","selfForZScoreResived":"Pharma Grade","supplierPort":"NEW YORK","supplierAddress":"200 FAIREFIELD AVENUE,WEST CALDWELL, NJ 07006SDNF US","customerAddress":"65 VETRI GARDEN NSK VAISHNAVI,SCHO"}]
    08-Mar-2021
    02-Jul-2024
    KGS
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    ABOUT THIS PAGE

    Anagrelide Hydrochloride Manufacturers

    A Anagrelide Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Anagrelide Hydrochloride, including repackagers and relabelers. The FDA regulates Anagrelide Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Anagrelide Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Anagrelide Hydrochloride manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Anagrelide Hydrochloride Suppliers

    A Anagrelide Hydrochloride supplier is an individual or a company that provides Anagrelide Hydrochloride active pharmaceutical ingredient (API) or Anagrelide Hydrochloride finished formulations upon request. The Anagrelide Hydrochloride suppliers may include Anagrelide Hydrochloride API manufacturers, exporters, distributors and traders.

    click here to find a list of Anagrelide Hydrochloride suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Anagrelide Hydrochloride USDMF

    A Anagrelide Hydrochloride DMF (Drug Master File) is a document detailing the whole manufacturing process of Anagrelide Hydrochloride active pharmaceutical ingredient (API) in detail. Different forms of Anagrelide Hydrochloride DMFs exist exist since differing nations have different regulations, such as Anagrelide Hydrochloride USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Anagrelide Hydrochloride DMF submitted to regulatory agencies in the US is known as a USDMF. Anagrelide Hydrochloride USDMF includes data on Anagrelide Hydrochloride's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Anagrelide Hydrochloride USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Anagrelide Hydrochloride suppliers with USDMF on PharmaCompass.

    Anagrelide Hydrochloride KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Anagrelide Hydrochloride Drug Master File in Korea (Anagrelide Hydrochloride KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Anagrelide Hydrochloride. The MFDS reviews the Anagrelide Hydrochloride KDMF as part of the drug registration process and uses the information provided in the Anagrelide Hydrochloride KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Anagrelide Hydrochloride KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Anagrelide Hydrochloride API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Anagrelide Hydrochloride suppliers with KDMF on PharmaCompass.

    Anagrelide Hydrochloride WC

    A Anagrelide Hydrochloride written confirmation (Anagrelide Hydrochloride WC) is an official document issued by a regulatory agency to a Anagrelide Hydrochloride manufacturer, verifying that the manufacturing facility of a Anagrelide Hydrochloride active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Anagrelide Hydrochloride APIs or Anagrelide Hydrochloride finished pharmaceutical products to another nation, regulatory agencies frequently require a Anagrelide Hydrochloride WC (written confirmation) as part of the regulatory process.

    click here to find a list of Anagrelide Hydrochloride suppliers with Written Confirmation (WC) on PharmaCompass.

    Anagrelide Hydrochloride NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Anagrelide Hydrochloride as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Anagrelide Hydrochloride API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Anagrelide Hydrochloride as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Anagrelide Hydrochloride and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Anagrelide Hydrochloride NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Anagrelide Hydrochloride suppliers with NDC on PharmaCompass.

    Anagrelide Hydrochloride GMP

    Anagrelide Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Anagrelide Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Anagrelide Hydrochloride GMP manufacturer or Anagrelide Hydrochloride GMP API supplier for your needs.

    Anagrelide Hydrochloride CoA

    A Anagrelide Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Anagrelide Hydrochloride's compliance with Anagrelide Hydrochloride specifications and serves as a tool for batch-level quality control.

    Anagrelide Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Anagrelide Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Anagrelide Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Anagrelide Hydrochloride EP), Anagrelide Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Anagrelide Hydrochloride USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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