DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

13 API Suppliers, 10 USDMF, 2 EU WC, 5 KDMF, 5 NDC API, 7 Listed Suppliers, $ API Reference Price

13 API Suppliers
10 USDMF
2 EU WC
5 KDMF
5 NDC API
7 Listed Suppliers
$ API Reference Price

INTERMEDIATES

4 Intermediates Suppliers

4 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

45 FDF Dossiers, 20 FDA Orange Book, 19 Europe, 2 Canada, 2 South Africa, 2 Listed Dossiers

45 FDF Dossiers
20 FDA Orange Book
19 Europe
2 Canada
2 South Africa
2 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 7 DKSH, 4 Faran Shimi Pharmaceutical, 8 Boai NKY Pharmaceuticals Ltd, 10 Gangwal Healthcare, 2 Nanjing Well Pharmaceutical, 4 ACG Worldwide, 1 Alcedo Pharmachem, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 15 BASF, 6 DFE Pharma, 1 Finar, 6 Gangwal Chemicals, 1 Ideal Cures Pvt Ltd, 1 Ingredion Pharma Solutions, 24 Kerry, 3 Lonza Capsugel, 12 Microlex e.U, 2 Novo Excipients, 3 Pharmatrans-Sanaq, 4 Pluviaendo, 3 Prachin Chemical, 1 Qualicaps, 10 Roquette, 1 Seppic, 4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 1 Shanghai Welltone Material Technology Co., Ltd, 10 Sigachi Industries, 2 Ulanqab Kema New Material, 1 Valens Pharmachem, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

61 Fillers, Diluents & Binders, 31 Direct Compression, 26 Disintegrants & Superdisintegrants, 20 Granulation, 18 Thickeners and Stabilizers, 16 Co-Processed Excipients, 11 Lubricants & Glidants, 11 Solubilizers, 9 Coating Systems & Additives, 8 Empty Capsules, 7 Controlled & Modified Release, 6 Film Formers & Plasticizers, 5 Chewable & Orodispersible Aids, 4 Parenteral, 3 Coloring Agents, 3 Topical, 3 Taste Masking, 2 Rheology Modifiers, 2 Emulsifying Agents, 1 API Stability Enhancers

DIGITAL CONTENT

6 NEWS #PharmaBuzz

media
6 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions, 19 Finished Drug Prices

globalSalesInformation
2 US Medicaid Prescriptions
19 Finished Drug Prices

MARKET PLACE

3 APIs, 5 FDF Dossiers

marketPlace
3 APIs
5 FDF Dossiers

REF. STANDARDS & IMPURITIES

3 USP , 17 Others

otherSolutions
3 USP
17 Others

ANALYTICAL

2 BioAnalytical Methods

otherMethods
2 BioAnalytical Methods

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 87,528

MARKET PLACE

API

FDF

4INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

10,311,147

Annual Reports (USD Million)

Finished Drug Prices

156 RELATED EXCIPIENT COMPANIES

247EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as:

Molecular Formula

C₁₀H₈Cl₃N₃O

Molecular Weight

292.5 g/mol

InChI Key

TVWRQCIPWUCNMI-UHFFFAOYSA-N

1 2D Structure

Anagrelide Hydrochloride

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one;hydrochloride

2.1.2 InChI

InChI=1S/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;/h1-2H,3-4H2,(H,13,14,16);1H

2.1.3 InChI Key

TVWRQCIPWUCNMI-UHFFFAOYSA-N

2.1.4 Canonical SMILES

C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl

2.1.5 Isomeric SMILES

C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl

2.2 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₁₀H₈Cl₃N₃O
Molecular Weight	292.5 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	0
Exact Mass	290.973295 g/mol
Monoisotopic Mass	290.973295 g/mol
Topological Polar Surface Area	44.7 A^2
Heavy Atom Count	17
Formal Charge	0
Complexity	360
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Agrylin
PubMed Health	Anagrelide (By mouth)
Drug Classes	Platelet Reducing Agent
Drug Label	Name: AGRYLIN (anagrelide hydrochloride)Dosage Form:0.5 mg capsules for oral administrationActive Ingredient:AGRYLIN Capsules contain 0.5 mg of anagrelide base (as anagrelide hydrochloride).Inactive Ingredients:Anhydrous Lactose NF, Crospov...
Active Ingredient	Anagrelide hydrochloride
Dosage Form	Capsule
Route	Oral
Strength	eq 0.5mg base
Market Status	Prescription
Company	Shire

2 of 4
Drug Name	Anagrelide hydrochloride
Drug Label	Anagrelide hydrochloride is an off white powder that is very slightly soluble in water and sparingly soluble in dimethyl sulfoxide and in dimethylformamide. Anagrelide hydrochloride is a platelet-reducing agent with a chemical name of 6,7-dichloro-1,...
Active Ingredient	Anagrelide hydrochloride
Dosage Form	Capsule
Route	Oral
Strength	eq 0.5mg base; eq 1mg base
Market Status	Prescription
Company	Mylan Pharms; Ivax Sub Teva Pharms; Mylan; Impax Labs; Barr

3 of 4
Drug Name	Agrylin
PubMed Health	Anagrelide (By mouth)
Drug Classes	Platelet Reducing Agent
Drug Label	Name: AGRYLIN (anagrelide hydrochloride)Dosage Form:0.5 mg capsules for oral administrationActive Ingredient:AGRYLIN Capsules contain 0.5 mg of anagrelide base (as anagrelide hydrochloride).Inactive Ingredients:Anhydrous Lactose NF, Crospov...
Active Ingredient	Anagrelide hydrochloride
Dosage Form	Capsule
Route	Oral
Strength	eq 0.5mg base
Market Status	Prescription
Company	Shire

4 of 4
Drug Name	Anagrelide hydrochloride
Drug Label	Anagrelide hydrochloride is an off white powder that is very slightly soluble in water and sparingly soluble in dimethyl sulfoxide and in dimethylformamide. Anagrelide hydrochloride is a platelet-reducing agent with a chemical name of 6,7-dichloro-1,...
Active Ingredient	Anagrelide hydrochloride
Dosage Form	Capsule
Route	Oral
Strength	eq 0.5mg base; eq 1mg base
Market Status	Prescription
Company	Mylan Pharms; Ivax Sub Teva Pharms; Mylan; Impax Labs; Barr

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

01

Chemwerth Inc

U.S.A

CPhI WW Frankfurt

Booth #12.1F43

ChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

Contact Supplier

U.S.A

Virtual Booth

Digital Content

Anagrelide Hydrochloride Monohydrate

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 16440

Submission : 2003-02-25

Status : Active

Type : II

02

Olainfarm Jsc

Latvia

CPHI Middle east

Not Confirmed

Olpha, a JSC AB City subsidiary, is a leading Baltic firm with 50 years of experience in medicines & chemical pharmaceuticals.

Contact Supplier

Latvia

Virtual Booth

Digital Content

Anagrelide Hydrochloride

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 17041

Submission : 2003-12-16

Status : Active

Type : II

03

Amsa Anonima Materie Sintetiche And ...

Italy

CPHI Middle east

Not Confirmed

04

Ash Stevens Inc

U.S.A

CPHI Middle east

Not Confirmed

05

Cipla Ltd

India

Country

CPHI Middle east

Not Confirmed

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EU WC

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KDMF

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NDC API

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Listed Suppliers

01

HRV Global Life Sciences

India

CPHI Middle east

Attending

HRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

Contact Supplier

India

Virtual Booth

Digital Content

Anagrelide Hydrochloride

About the Company : HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It...

HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It offers services such as sourcing, manufacturing & supply, helping partners enter new markets worldwide. Its strong partnerships with major players in the pharma and food additive industries help HRV Global effectively promote projects and products. HRV Global represents over 30 large Indian drugmakers, primarily targeting Europe, the US & the Middle East markets. Headquartered in India, HRV Global has offices in the US, Switzerland, Dubai, Lithuania & Turkey.

02

Cipla

India

Medlab Asia & Asia Health

Not Confirmed

03

CPL Sachse

Germany

Medlab Asia & Asia Health

Not Confirmed

04

Mehta API

India

India

Medlab Asia & Asia Health

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

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Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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Lubricants & Glidants

Solubilizers

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Empty Capsules

Controlled & Modified Release

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ABOUT THIS PAGE

Find Anagrelide Hydrochloride manufacturers, exporters & distributors on PharmaCompass

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CHEMISTRY

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ACTIVE PHARMA INGREDIENTS

13 API Suppliers

10 USDMF

2 EU WC

5 KDMF

5 NDC API

7 Listed Suppliers

$ API Reference Price

INTERMEDIATES

4 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

45 FDF Dossiers

20 FDA Orange Book

19 Europe

2 Canada

2 South Africa

2 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 SPI Pharma

7 DKSH

4 Faran Shimi Pharmaceutical

8 Boai NKY Pharmaceuticals Ltd

10 Gangwal Healthcare

2 Nanjing Well Pharmaceutical

4 ACG Worldwide

1 Alcedo Pharmachem

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

15 BASF

6 DFE Pharma

1 Finar

6 Gangwal Chemicals

1 Ideal Cures Pvt Ltd

1 Ingredion Pharma Solutions

24 Kerry

3 Lonza Capsugel

12 Microlex e.U

2 Novo Excipients

3 Pharmatrans-Sanaq

4 Pluviaendo

3 Prachin Chemical

1 Qualicaps

10 Roquette

1 Seppic

4 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

1 Shanghai Welltone Material Technology Co., Ltd

10 Sigachi Industries

2 Ulanqab Kema New Material

1 Valens Pharmachem

3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

61 Fillers, Diluents & Binders

31 Direct Compression

26 Disintegrants & Superdisintegrants

20 Granulation

18 Thickeners and Stabilizers

16 Co-Processed Excipients

11 Lubricants & Glidants

11 Solubilizers

9 Coating Systems & Additives

8 Empty Capsules

7 Controlled & Modified Release

6 Film Formers & Plasticizers

5 Chewable & Orodispersible Aids

4 Parenteral

3 Coloring Agents

3 Topical

3 Taste Masking

2 Rheology Modifiers

2 Emulsifying Agents

1 API Stability Enhancers

DIGITAL CONTENT

6 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

2 US Medicaid Prescriptions

19 Finished Drug Prices