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Chemistry

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Also known as:
Molecular Formula
C10H8Cl3N3O
Molecular Weight
292.5  g/mol
InChI Key
TVWRQCIPWUCNMI-UHFFFAOYSA-N

Anagrelide Hydrochloride
1 2D Structure

Anagrelide Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
6,7-dichloro-5,10-dihydro-3H-imidazo[2,1-b]quinazolin-2-one;hydrochloride
2.1.2 InChI
InChI=1S/C10H7Cl2N3O.ClH/c11-6-1-2-7-5(9(6)12)3-15-4-8(16)14-10(15)13-7;/h1-2H,3-4H2,(H,13,14,16);1H
2.1.3 InChI Key
TVWRQCIPWUCNMI-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl
2.1.5 Isomeric SMILES
C1C2=C(C=CC(=C2Cl)Cl)NC3=NC(=O)CN31.Cl
2.2 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 292.5 g/mol
Molecular Formula C10H8Cl3N3O
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count0
Exact Mass290.973295 g/mol
Monoisotopic Mass290.973295 g/mol
Topological Polar Surface Area44.7 A^2
Heavy Atom Count17
Formal Charge0
Complexity360
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 4  
Drug NameAgrylin
PubMed HealthAnagrelide (By mouth)
Drug ClassesPlatelet Reducing Agent
Drug LabelName: AGRYLIN (anagrelide hydrochloride)Dosage Form:0.5 mg capsules for oral administrationActive Ingredient:AGRYLIN Capsules contain 0.5 mg of anagrelide base (as anagrelide hydrochloride).Inactive Ingredients:Anhydrous Lactose NF, Crospov...
Active IngredientAnagrelide hydrochloride
Dosage FormCapsule
RouteOral
Strengtheq 0.5mg base
Market StatusPrescription
CompanyShire

2 of 4  
Drug NameAnagrelide hydrochloride
Drug LabelAnagrelide hydrochloride is an off white powder that is very slightly soluble in water and sparingly soluble in dimethyl sulfoxide and in dimethylformamide. Anagrelide hydrochloride is a platelet-reducing agent with a chemical name of 6,7-dichloro-1,...
Active IngredientAnagrelide hydrochloride
Dosage FormCapsule
RouteOral
Strengtheq 0.5mg base; eq 1mg base
Market StatusPrescription
CompanyMylan Pharms; Ivax Sub Teva Pharms; Mylan; Impax Labs; Barr

3 of 4  
Drug NameAgrylin
PubMed HealthAnagrelide (By mouth)
Drug ClassesPlatelet Reducing Agent
Drug LabelName: AGRYLIN (anagrelide hydrochloride)Dosage Form:0.5 mg capsules for oral administrationActive Ingredient:AGRYLIN Capsules contain 0.5 mg of anagrelide base (as anagrelide hydrochloride).Inactive Ingredients:Anhydrous Lactose NF, Crospov...
Active IngredientAnagrelide hydrochloride
Dosage FormCapsule
RouteOral
Strengtheq 0.5mg base
Market StatusPrescription
CompanyShire

4 of 4  
Drug NameAnagrelide hydrochloride
Drug LabelAnagrelide hydrochloride is an off white powder that is very slightly soluble in water and sparingly soluble in dimethyl sulfoxide and in dimethylformamide. Anagrelide hydrochloride is a platelet-reducing agent with a chemical name of 6,7-dichloro-1,...
Active IngredientAnagrelide hydrochloride
Dosage FormCapsule
RouteOral
Strengtheq 0.5mg base; eq 1mg base
Market StatusPrescription
CompanyMylan Pharms; Ivax Sub Teva Pharms; Mylan; Impax Labs; Barr

API SUPPLIERS

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ChemWerth Inc

U.S.A

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HRV Global Life Sciences

India

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Virtual BoothHRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

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Olpha

Latvia

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Pharma, Lab & Chemical Expo
Not Confirmed
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Virtual BoothOlpha, a JSC AB City subsidiary, is a leading Baltic firm with 50 years of experience in medicines & chemical pharmaceuticals.

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Micro Labs Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Micro Labs Limited

India

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Torrent Pharmaceuticals Limited

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Torrent Pharmaceuticals Limited

India

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Cipla

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Cipla

India

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Zydus Lifesciences

India

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Zydus Lifesciences

India

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Piramal Pharma Solutions

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Piramal Pharma Solutions

U.S.A

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Ash Stevens

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Ash Stevens

U.S.A

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Amsa Spa

Italy

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Amsa Spa

Italy

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USDMF

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Virtual BoothChemWerth works in generic API development & supply, non-infringement patent strategy development and regulatory support.

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GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 16440

Submission : 2003-02-25

Status : Active

Type : II

Chemwerth Compnay Banner

02

Olainfarm Jsc

Latvia
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CPHI Middle east
Not Confirmed
  • fda
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Virtual BoothOlpha, a JSC AB City subsidiary, is a leading Baltic firm with 50 years of experience in medicines & chemical pharmaceuticals.

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DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 17041

Submission : 2003-12-16

Status : Active

Type : II

Olpha

03

CPHI Middle east
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04

Ash Stevens Inc

U.S.A

USDMF

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CPHI Middle east
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04

CPHI Middle east
Not Confirmed

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 15971

Submission : 2002-05-06

Status : Active

Type : II

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Cipla Ltd

India

USDMF

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CPHI Middle east
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Cipla Ltd

India
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CPHI Middle east
Not Confirmed

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DMF Review : N/A

Rev. Date :

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DMF Number : 16024

Submission : 2002-06-24

Status : Active

Type : II

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Micro Labs Ltd

India

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CPHI Middle east
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CPHI Middle east
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DMF Review : Complete

Rev. Date : 2022-06-23

Pay. Date : 2022-06-08

DMF Number : 37180

Submission : 2022-06-01

Status : Active

Type : II

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Piramal Pharma Ltd

U.S.A

USDMF

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08

CPHI Middle east
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CPHI Middle east
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GDUFA

DMF Review : Complete

Rev. Date : 2015-10-02

Pay. Date : 2015-06-30

DMF Number : 29475

Submission : 2015-07-13

Status : Active

Type : II

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CPHI Middle east
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CPHI Middle east
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DMF Review : Complete

Rev. Date : 2014-11-14

Pay. Date : 2014-06-11

DMF Number : 16531

Submission : 2003-03-30

Status : Active

Type : II

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Chemisch Pharmazeutisches Labor Rolf...

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DMF Review : N/A

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DMF Number : 18240

Submission : 2005-02-25

Status : Inactive

Type : II

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Listed Suppliers

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01

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Virtual BoothHRV Global Life Sciences - Market Expansion Leader in Pharmaceuticals.

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Anagrelide Hydrochloride

About the Company : HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It...

HRV Global is a leading global manufacturer, seller & exporter of a wide range of APIs, advanced intermediates, pellets, food grade chemicals, food additives & food ingredients. It offers services such as sourcing, manufacturing & supply, helping partners enter new markets worldwide. Its strong partnerships with major players in the pharma and food additive industries help HRV Global effectively promote projects and products. HRV Global represents over 30 large Indian drugmakers, primarily targeting Europe, the US & the Middle East markets. Headquartered in India, HRV Global has offices in the US, Switzerland, Dubai, Lithuania & Turkey.
HRV Global Life Sciences

02

Cipla

India
Medlab Asia & Asia Health
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Cipla

India
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Anagrelide

About the Company : Cipla is a global pharmaceutical company whose goal is ensuring no patient shall be denied access to high quality & affordable medicine and support. Mission: Cipla’s mission i...

Cipla is a global pharmaceutical company whose goal is ensuring no patient shall be denied access to high quality & affordable medicine and support. Mission: Cipla’s mission is to be a leading global healthcare company which uses technology and innovation to meet everyday needs of all patients. Since inception in 1935, caring has been at the core of everything we do at Cipla. For patients, caring is a promise that we will do whatever it takes to ensure they have continued access to the highest quality medicines at affordable prices; whether a disease affects millions or just a few hundreds.
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CPL Sachse

Germany
Medlab Asia & Asia Health
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CPL Sachse

Germany
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Medlab Asia & Asia Health
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Anagrelide Hydrochloride Monohydrate

About the Company : CPL Sachse is a contract development and manufacturing organization specializing in the production of organic pharmaceutical active ingredients for both human and veterinary medica...

CPL Sachse is a contract development and manufacturing organization specializing in the production of organic pharmaceutical active ingredients for both human and veterinary medical applications. Our manufacturing processes adhere to current Good Manufacturing Practices (cGMP) as outlined in the EU GMP Guide Part II (ICH Q7). We undergo regular monitoring by the relevant local authority, which issues us GMP certificates specifically for our active ingredients.
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Mehta API

India
Medlab Asia & Asia Health
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Mehta API

India
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Anagrelide

About the Company : Mehta API Pvt Ltd engaged in manufacturing and marketing of APIs & Advance Drug Intermediates.... Globally. Mehta Api has been inordinately proud of its achievements since its ince...

Mehta API Pvt Ltd engaged in manufacturing and marketing of APIs & Advance Drug Intermediates.... Globally. Mehta Api has been inordinately proud of its achievements since its inception .Our journey is paved with many success stories. Much of it has, in many ways, been unprecedented in the Pharma industry. Our success has been validated by what we hold the dearest - Product Excellence and Customer service. We believe that long-term business success is rooted in value. Business ethics are good business; they are like a long-term insurance policy. We are committed to Excellence in Product Quality and adherence to stringent delivery schedule.
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Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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Anagrelide Hydrochloride

About the Company : Micro Labs Limited is a diversified healthcare company with cutting-edge R&D, advanced manufacturing facilities, and a strong distribution network. It ranks among India's top pharm...

Micro Labs Limited is a diversified healthcare company with cutting-edge R&D, advanced manufacturing facilities, and a strong distribution network. It ranks among India's top pharmaceutical companies, with a leading presence in cardiology, diabetology, anti-infectives, ophthalmology, and pain management. The company is known for its high-quality medicines, including the popular fever management brand, Dolo. Micro Labs continues to grow through innovation, research, and global expansion, delivering healthcare solutions that meet international standards.
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Medlab Asia & Asia Health
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Medlab Asia & Asia Health
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Anagrelide Hydrochloride

About the Company : Torrent Pharma is part of 3 billion USD Torrent group; we are leading conglomerate from India, having presence across 40 countries including USA, Brazil, Europe, and Mexico & India...

Torrent Pharma is part of 3 billion USD Torrent group; we are leading conglomerate from India, having presence across 40 countries including USA, Brazil, Europe, and Mexico & India. Over the years, Torrent forayed into Dermatology & Oncology segment for which Torrent is actively looking for partners to provide Contract Manufacturing Services for India as well as Global markets. Torrent has state of the art manufacturing facility based in India and has capability to handle various types of Derma & Onco products with available capacity of more than 150 Mn units & 50 Mn units per Annum respectively.
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Medlab Asia & Asia Health
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Anagrelide

About the Company : Zydus Cadila is headquartered in Ahmedabad, India, and ranks 4th in the Indian pharmaceutical industry. The group has manufacturing sites and research facilities spread across five...

Zydus Cadila is headquartered in Ahmedabad, India, and ranks 4th in the Indian pharmaceutical industry. The group has manufacturing sites and research facilities spread across five states of Gujarat, Maharashtra, Goa, Himachal Pradesh and Sikkim in India and in the US and Brazil. Zydus’ global business has a strong presence in the regulated markets of the US, Europe (France and Spain) and in the high profile markets of Latin America and South Africa. It is also present in a big way in 25 other emerging markets worldwide.
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API Reference Price

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01-Apr-2021
31-Aug-2024
KGS
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Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

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