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1. 4,9(11)-pregnadien-17alpha,21-diol-3,20-dione-21-acetate
1. 7753-60-8
2. Retaane
3. Al 3789
4. Al-3789
5. Anecortave Acetate [usan]
6. Nsc 15475
7. Nsc 24345
8. Anecortave [inn]
9. Nsc-15475
10. Nsc-24345
11. 17,21-dihydroxypregna-4,9(11)-diene-3,20-dione 21-acetate
12. Y0pc411k4t
13. 21-(acetyloxy)-17-hydroxypregna-4,9(11)-diene-3,20-dione
14. [2-[(8s,10s,13s,14s,17r)-17-hydroxy-10,13-dimethyl-3-oxo-2,6,7,8,12,14,15,16-octahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] Acetate
15. 17-hydroxy-3,20-dioxopregna-4,9(11)-dien-21-yl Acetate
16. Anecortave Acetate (200 Mg)f0e2980.997mg/mg(ai)
17. Retaane Suspension
18. Unii-y0pc411k4t
19. Anecortave-acetate
20. Ncgc00181018-01
21. Einecs 231-812-5
22. Anecortave [mart.]
23. Dsstox_cid_26805
24. Dsstox_rid_81919
25. Dsstox_gsid_46805
26. Schembl94110
27. 17-hydroxy-3,20-dioxopregna-4,9(11)-dien-21-yl Acetate #
28. Anecortave Acetate [mi]
29. Anecortave Acetate (jan/usan)
30. Anecortave Acetate [jan]
31. Chembl2106613
32. Dtxsid5046805
33. Chebi:31215
34. Ex-a5253
35. Nsc15475
36. Nsc24345
37. Zinc3931050
38. Tox21_112668
39. 17-alpha,21-dihydroxypregna-4,9(11)-diene-3,20-dione 21-acetate
40. Akos015917580
41. Db05288
42. Cas-7753-60-8
43. Hy-116868
44. Cs-0066714
45. D01733
46. Q4761567
47. Hydrocortisone Acetate Impurity E [ep Impurity]
48. 21-acetoxy-17-hydroxy-4,9(11)-pregnadiene-3,20-dione
49. 17alpha-hydroxy-21-acetoxypregna-4,9(11)-diene-3,20-dione
50. 4,9(11)-pregnadien-17alpha,21-diol-3,20-dione-21-acetate
51. Pregn-4,9(11)-dien-17,21-diol-3,20-dione, Acetate(ester)
52. 17alpha-hydroxy-21 -acetoxy-pregna-4,9(11)-diene-3,20-dione
53. Pregna-4,9(11)-diene-3,20-dione, 21-(acetyloxy)-17-hydroxy-
| Molecular Weight | 386.5 g/mol |
|---|---|
| Molecular Formula | C23H30O5 |
| XLogP3 | 2.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 4 |
| Exact Mass | 386.20932405 g/mol |
| Monoisotopic Mass | 386.20932405 g/mol |
| Topological Polar Surface Area | 80.7 Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 808 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 5 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Investigated for use/treatment in glaucoma and macular degeneration.
Anecortave acetate functions as an antiangiogenic agent, inhibiting blood vessel growth by decreasing extracellular protease expression and inhibiting endothelial cell migration. Its angiostatic activity does not seem to be mediated through any of the commonly known pharmacological receptors. (Ophthalmology 2004;111:2316-7) RETAANE blocks signals from multiple growth factors because it acts downstream and independent of the initiating angiogenic stimuli and inhibits angiogenesis subsequent to the angiogenic stimulation.
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ABOUT THIS PAGE
A Anecortave Acetate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Anecortave Acetate, including repackagers and relabelers. The FDA regulates Anecortave Acetate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Anecortave Acetate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Anecortave Acetate supplier is an individual or a company that provides Anecortave Acetate active pharmaceutical ingredient (API) or Anecortave Acetate finished formulations upon request. The Anecortave Acetate suppliers may include Anecortave Acetate API manufacturers, exporters, distributors and traders.
click here to find a list of Anecortave Acetate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Anecortave Acetate DMF (Drug Master File) is a document detailing the whole manufacturing process of Anecortave Acetate active pharmaceutical ingredient (API) in detail. Different forms of Anecortave Acetate DMFs exist exist since differing nations have different regulations, such as Anecortave Acetate USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Anecortave Acetate DMF submitted to regulatory agencies in the US is known as a USDMF. Anecortave Acetate USDMF includes data on Anecortave Acetate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Anecortave Acetate USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Anecortave Acetate suppliers with USDMF on PharmaCompass.
Anecortave Acetate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Anecortave Acetate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Anecortave Acetate GMP manufacturer or Anecortave Acetate GMP API supplier for your needs.
A Anecortave Acetate CoA (Certificate of Analysis) is a formal document that attests to Anecortave Acetate's compliance with Anecortave Acetate specifications and serves as a tool for batch-level quality control.
Anecortave Acetate CoA mostly includes findings from lab analyses of a specific batch. For each Anecortave Acetate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Anecortave Acetate may be tested according to a variety of international standards, such as European Pharmacopoeia (Anecortave Acetate EP), Anecortave Acetate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Anecortave Acetate USP).
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