Find Angiotensin III manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Angiotensin iii, human, 12687-51-3, Angiotensin iii, human, mouse, 13602-53-4, Chebi:89666, (2s)-2-[[(2s)-1-[(2s)-2-[[(2s,3s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1h-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Molecular Formula
C46H66N12O9
Molecular Weight
931.1  g/mol
InChI Key
QMMRCKSBBNJCMR-KMZPNFOHSA-N

Angiotensin III
A heptapeptide formed from ANGIOTENSIN II after the removal of an amino acid at the N-terminal by AMINOPEPTIDASE A. Angiotensin III has the same efficacy as ANGIOTENSIN II in promoting ALDOSTERONE secretion and modifying renal blood flow, but less vasopressor activity (about 40%).
1 2D Structure

Angiotensin III

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
2.1.2 InChI
InChI=1S/C46H66N12O9/c1-5-27(4)38(57-40(61)33(21-29-15-17-31(59)18-16-29)53-42(63)37(26(2)3)56-39(60)32(47)13-9-19-51-46(48)49)43(64)54-34(23-30-24-50-25-52-30)44(65)58-20-10-14-36(58)41(62)55-35(45(66)67)22-28-11-7-6-8-12-28/h6-8,11-12,15-18,24-27,32-38,59H,5,9-10,13-14,19-23,47H2,1-4H3,(H,50,52)(H,53,63)(H,54,64)(H,55,62)(H,56,60)(H,57,61)(H,66,67)(H4,48,49,51)/t27-,32-,33-,34-,35-,36-,37-,38-/m0/s1
2.1.3 InChI Key
QMMRCKSBBNJCMR-KMZPNFOHSA-N
2.1.4 Canonical SMILES
CCC(C)C(C(=O)NC(CC1=CN=CN1)C(=O)N2CCCC2C(=O)NC(CC3=CC=CC=C3)C(=O)O)NC(=O)C(CC4=CC=C(C=C4)O)NC(=O)C(C(C)C)NC(=O)C(CCCN=C(N)N)N
2.1.5 Isomeric SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC3=CC=CC=C3)C(=O)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCCN=C(N)N)N
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Angiotensin Ii, Des-asp

2. Des Asp Angiotensin Ii

3. Des Aspartyl Angiotensin Ii

4. Des-asp Angiotensin Ii

5. Des-aspartyl-angiotensin Ii

2.2.2 Depositor-Supplied Synonyms

1. Angiotensin Iii, Human

2. 12687-51-3

3. Angiotensin Iii, Human, Mouse

4. 13602-53-4

5. Chebi:89666

6. (2s)-2-[[(2s)-1-[(2s)-2-[[(2s,3s)-2-[[(2s)-2-[[(2s)-2-[[(2s)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1h-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic Acid

7. 5-ile-angiotensin Iii

8. Unii-xh7f04lxtf

9. Angiotensin Iii, 5-ile-

10. 1-desaspartyl-5-isoleucine Angiotensin Ii

11. Des-asp(1)-(ile(5))-angiotensin Ii

12. Angiotensin Ii, 1-desaspartyl-5-isoleucine-

13. Xh7f04lxtf

14. Des-asp-1-angiotensin Ii

15. Schembl9010604

16. Chembl1702539

17. Bdbm85557

18. Hy-p1540

19. Mfcd00167500

20. Akos024456669

21. Zinc169289390

22. Ncgc00167131-01

23. Cas_12687-51-3

24. Angiotensin Iii Trifluoroacetate Salt Hydrate

25. Cs-0044838

26. 1-de-l-aspartic Acid-5-l-isoleucine-angiotensin Ii

27. Angiotensin Iii (h-l-arg-l-val-l-tyr-l-ile-l-his-l-pro-l-phe-oh)

28. (2s)-2-{[(2s)-1-[(2s)-2-[(2s,3s)-2-[(2s)-2-[(2s)-2-[(2s)-2-amino-5-[(diaminomethylidene)amino]pentanamido]-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-methylpentanamido]-3-(1h-imidazol-5-yl)propanoyl]pyrrolidin-2-yl]formamido}-3-phenylpropanoic Acid

29. (s)-2-((s)-1-((6s,9s,12s,15s,18s)-18-((1h-imidazol-4-yl)methyl)-1,6-diamino-15-sec-butyl-12-(4-hydroxybenzyl)-1-imino-9-isopropyl-7,10,13,16-tetraoxo-2,8,11,14,17-pentaazanonadecane)pyrrolidine-2-carboxamido)-3-phenylpropanoic Acid

2.3 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 931.1 g/mol
Molecular Formula C46H66N12O9
XLogP3-0.5
Hydrogen Bond Donor Count11
Hydrogen Bond Acceptor Count12
Rotatable Bond Count25
Exact Mass930.50757173 g/mol
Monoisotopic Mass930.50757173 g/mol
Topological Polar Surface Area342 Ų
Heavy Atom Count67
Formal Charge0
Complexity1680
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ANALYTICAL

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ABOUT THIS PAGE

Angiotensin III Manufacturers

A Angiotensin III manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Angiotensin III, including repackagers and relabelers. The FDA regulates Angiotensin III manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Angiotensin III API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Angiotensin III Suppliers

A Angiotensin III supplier is an individual or a company that provides Angiotensin III active pharmaceutical ingredient (API) or Angiotensin III finished formulations upon request. The Angiotensin III suppliers may include Angiotensin III API manufacturers, exporters, distributors and traders.

Angiotensin III GMP

Angiotensin III Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Angiotensin III GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Angiotensin III GMP manufacturer or Angiotensin III GMP API supplier for your needs.

Angiotensin III CoA

A Angiotensin III CoA (Certificate of Analysis) is a formal document that attests to Angiotensin III's compliance with Angiotensin III specifications and serves as a tool for batch-level quality control.

Angiotensin III CoA mostly includes findings from lab analyses of a specific batch. For each Angiotensin III CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Angiotensin III may be tested according to a variety of international standards, such as European Pharmacopoeia (Angiotensin III EP), Angiotensin III JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Angiotensin III USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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