Find Anlotinib Hydrochloride manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Anlotinib hcl, 1360460-82-7, Anlotinib hydrochloride, Al3818 dihydrochloride, Catequentinib hydrochloride, Catequentinib dihydrochloride
Molecular Formula
C23H24Cl2FN3O3
Molecular Weight
480.4  g/mol
InChI Key
UUAKQNIPIXQZFN-UHFFFAOYSA-N
FDA UNII
A3749M6582

Anlotinib Hydrochloride
CATEQUENTINIB HYDROCHLORIDE is a small molecule drug with a maximum clinical trial phase of I and has 1 investigational indication.
1 2D Structure

Anlotinib Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinolin-7-yl]oxymethyl]cyclopropan-1-amine;dihydrochloride
2.1.2 InChI
InChI=1S/C23H22FN3O3.2ClH/c1-13-9-15-16(27-13)3-4-19(22(15)24)30-18-5-8-26-17-11-21(20(28-2)10-14(17)18)29-12-23(25)6-7-23;;/h3-5,8-11,27H,6-7,12,25H2,1-2H3;2*1H
2.1.3 InChI Key
UUAKQNIPIXQZFN-UHFFFAOYSA-N
2.2 Other Identifiers
2.2.1 UNII
A3749M6582
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. Anlotinib Hcl

2. 1360460-82-7

3. Anlotinib Hydrochloride

4. Al3818 Dihydrochloride

5. Catequentinib Hydrochloride

6. Catequentinib Dihydrochloride

7. A3749m6582

8. 1360460-82-7 (hcl)

9. 1-[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-6-methoxyquinolin-7-yl]oxymethyl]cyclopropan-1-amine;dihydrochloride

10. Catequentinib Hydrochloride (usan)

11. Anlotinib 2hcl

12. 1-(((4-((4-fluoro-2-methyl-1h-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropan-1-amine Dihydrochloride

13. 1-[({4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-6-methoxyquinolin-7-yl}oxy)methyl]cyclopropan-1-amine Dihydrochloride

14. Catequentinib Hydrochloride [usan]

15. 1-[[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]cyclopropanamine Hydrochloride (1:2); Al3818 Dihydrochloride

16. Chembl5314570

17. Schembl18691323

18. Al-3818 Dihydrochloride

19. Unii-a3749m6582

20. Bcp19682

21. Anlotinib (al3818) Dihydrochloride

22. Hy-19716a

23. S8726

24. Ccg-269545

25. Catequentinib Hydrochloride [who-dd]

26. Cs-0040093

27. D12537

28. D72434

29. 1-((4-((4-fluoro-2-methyl-1h-indol-5-yl)oxy)-6-methoxy-7-quinolyl)oxymethyl)cyclopropanamine, Dihydrochloride

30. 1-[[[4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yl]oxy]methyl]cyclopropanamine Dihydrochloride

31. Cyclopropanamine, 1-(((4-((4-fluoro-2-methyl-1h-indol-5-yl)oxy)-6-methoxy-7-quinolinyl)oxy)methyl)-, Hydrochloride (1:2)

32. Cyclopropanamine, 1-[[[4-[(4-fluoro-2-methyl-1h-indol-5-yl)oxy]-6-methoxy-7-quinoliny]oxy]methyl]-, Hydrochloride (1:2)

2.3.2 Other Synonyms

1. 1058156-90-3

2. Anlotinib

2.4 Create Date
2012-07-16
3 Chemical and Physical Properties
Molecular Weight 480.4 g/mol
Molecular Formula C23H24Cl2FN3O3
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area82.4
Heavy Atom Count32
Formal Charge0
Complexity606
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3

Drugs in Development

read-more
read-more

Details:

AK105 (penpulimab) is a differentiated PD-1 monoclonal antibody, which is being evaluated in combination with Anlotinib HCl for the first-line (1L) treatment of advanced hepatocellular carcinoma.


Lead Product(s): Penpulimab,Anlotinib Hydrochloride

Therapeutic Area: Oncology Brand Name: AK105

Study Phase: Phase IIIProduct Type: Large molecule

Sponsor: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable November 22, 2024

blank

01

Akeso

China
arrow
BIO Partnering at JPM
Not Confirmed

Akeso

China
arrow
BIO Partnering at JPM
Not Confirmed

Details : AK105 (penpulimab) is a differentiated PD-1 monoclonal antibody, which is being evaluated in combination with Anlotinib HCl for the first-line (1L) treatment of advanced hepatocellular carcinoma.

Brand Name : AK105

Molecule Type : Large molecule

Upfront Cash : Not Applicable

November 22, 2024

blank
Full Screen ViewFULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty