Find Apalutamide manufacturers, exporters & distributors on PharmaCompass

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

Virtual Booth

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

26 API Suppliers, 11 USDMF, 4 EU WC, 1 KDMF, 8 NDC API, 21 Listed Suppliers, $ API Reference Price

26 API Suppliers
11 USDMF
4 EU WC
1 KDMF
8 NDC API
21 Listed Suppliers
$ API Reference Price

DEVELOPMENTS

17 Drugs in Development

17 Drugs in Development

INTERMEDIATES

17 Intermediates Suppliers

17 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

10 FDF Dossiers, 2 FDA Orange Book, 2 Europe, 2 Canada, 2 Australia, 1 South Africa, 1 Listed Dossiers

10 FDF Dossiers
2 FDA Orange Book
2 Europe
2 Canada
2 Australia
1 South Africa
1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 2 Seqens, 4 DKSH, 2 Faran Shimi Pharmaceutical, 7 Gangwal Healthcare, 3 Actylis, 1 Aeon Procare, 5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 9 BASF, 5 Corel Pharma Chem, 3 DFE Pharma, 1 Finar, 7 Gangwal Chemicals, 3 Ideal Cures Pvt Ltd, 1 Ingredion Pharma Solutions, 6 Kerry, 7 Microlex e.U, 2 Nomisma Healthcare, 1 Novo Excipients, 1 Pharmatrans-Sanaq, 2 Pluviaendo, 3 Prachin Chemical, 10 Roquette, 3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 10 Sigachi Industries, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

22 Fillers, Diluents & Binders, 20 Coating Systems & Additives, 15 Thickeners and Stabilizers, 15 Disintegrants & Superdisintegrants, 14 Direct Compression, 13 Controlled & Modified Release, 13 Lubricants & Glidants, 8 Topical, 8 Co-Processed Excipients, 8 Granulation, 4 Film Formers & Plasticizers, 4 Solubilizers, 3 Coloring Agents, 3 Emulsifying Agents, 3 Parenteral, 3 Taste Masking, 2 Rheology Modifiers, 2 Chewable & Orodispersible Aids, 2 API Stability Enhancers

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow, 52 NEWS #PharmaBuzz

media
3 DATA COMPILATION #PharmaFlow
52 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 2 Finished Drug Prices, 4 Annual Reports

globalSalesInformation
1 US Medicaid Prescriptions
2 Finished Drug Prices
4 Annual Reports

MARKET PLACE

5 APIs, 5 FDF Dossiers

marketPlace
5 APIs
5 FDF Dossiers

PATENTS & EXCLUSIVITIES

28 US Patents

patents
28 US Patents

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 11,442

MARKET PLACE

API

FDF

17INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

17DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

877,671,428

Annual Reports (USD Million)

6,319

Finished Drug Prices

102 RELATED EXCIPIENT COMPANIES

162EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Arn-509, 956104-40-8, Erleada, Jnj-56021927, Arn 509, Apalutamide [inn]

Molecular Formula

C₂₁H₁₅F₄N₅O₂S

Molecular Weight

477.4 g/mol

InChI Key

HJBWBFZLDZWPHF-UHFFFAOYSA-N

FDA UNII

4T36H88UA7

Apalutamide is a small molecule and androgen receptor (AR) antagonist with potential antineoplastic activity. Apalutamide binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR-responsive genes. This ultimately inhibits the expression of genes that regulate prostate cancer cell proliferation and may lead to an inhibition of cell growth in AR-expressing tumor cells.

1 2D Structure

Apalutamide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-[7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-N-methylbenzamide

2.1.2 InChI

InChI=1S/C21H15F4N5O2S/c1-27-17(31)13-4-3-11(8-15(13)22)30-19(33)29(18(32)20(30)5-2-6-20)12-7-14(21(23,24)25)16(9-26)28-10-12/h3-4,7-8,10H,2,5-6H2,1H3,(H,27,31)

2.1.3 InChI Key

HJBWBFZLDZWPHF-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CC(=C(N=C4)C#N)C(F)(F)F)F

2.2 Other Identifiers

2.2.1 UNII

4T36H88UA7

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Arn-509

2. Erleada

2.3.2 Depositor-Supplied Synonyms

1. Arn-509

2. 956104-40-8

3. Erleada

4. Jnj-56021927

5. Arn 509

6. Apalutamide [inn]

7. Arn509

8. Apalutamide (arn-509)

9. 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro[3.4]octan-5-yl)-2-fluoro-n-methylbenzamide

10. 4t36h88ua7

11. 956104-40-8 (free Base)

12. 4-[7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl]-2-fluoro-n-methylbenzamide

13. 4-{7-[6-cyano-5-(trifluoromethyl)pyridin-3-yl]-8-oxo-6-sulfanylidene-5,7-diazaspiro[3.4]octan-5-yl}-2-fluoro-n-methylbenzamide

14. 4-(7-(6-cyano-5-(trifluoromethyl)pyridin-3-yl)-8-oxo-6-thioxo-5,7-diazaspiro(3.4)octan-5-yl)-2-fluoro-n-methylbenzamide

15. Unii-4t36h88ua7

16. Ar509

17. Apalutamidearn509

18. Erleada (tn)

19. Jnj 56021927

20. Apalutamide (jan/inn)

21. Apalutamide [mi]

22. Apalutamide [jan]

23. Apalutamide [who-dd]

24. Mls006011109

25. Schembl909297

26. Gtpl9043

27. Chembl3183409

28. Apalutamide [orange Book]

29. Dtxsid40241899

30. Ex-a089

31. Hms3656n12

32. Amy24182

33. Bcp05829

34. Ar509/ar-509

35. Bdbm50094975

36. Mfcd22380626

37. Nsc771649

38. Nsc794776

39. S2840

40. Zinc43174901

41. Akos025401932

42. Ccg-264760

43. Cs-0885

44. Db11901

45. Nsc-771649

46. Nsc-794776

47. Pb27306

48. Ncgc00346725-01

49. Ncgc00346725-02

50. Ncgc00346725-06

51. Ac-27403

52. As-35181

53. Hy-16060

54. Smr004702891

55. Sw220300-1

56. 24872560, Erleada, C21h15f4n5o2s

57. D11040

58. J-519596

59. Q21098975

60. Benzamide, 4-(7-(6-cyano-5-(trifluoromethyl)-3-pyridinyl)-8-oxo-6-thioxo-5,7-diazaspiro(3.4)oct-5-yl)-2-fluoro-n-methyl-

2.4 Create Date

2008-08-18

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₁₅F₄N₅O₂S
Molecular Weight	477.4 g/mol
XLogP3	3
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	3
Exact Mass	477.08825856 g/mol
Monoisotopic Mass	477.08825856 g/mol
Topological Polar Surface Area	121 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	886
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

Indicated for the treatment of patients with non-metastatic, castration-resistant prostate cancer (NM-CRPC).

FDA Label

Erleada is indicated:

in adult men for the treatment of non metastatic castration resistant prostate cancer (nmCRPC) who are at high risk of developing metastatic disease. in adult men for the treatment of metastatic hormone-sensitive prostate cancer (mHSPC) in combination with androgen deprivation therapy (ADT).

5 Pharmacology and Biochemistry

5.1 Pharmacology

In an open-label, uncontrolled, multi-center, single-arm dedicated QT study in 45 patients with CRPC, an exposure-QT analysis suggested a concentration-dependent increase in QTcF for apalutamide and its active metabolite. Apalutamide demonstrated an antitumor activity in the mouse xenograft models of prostate cancer, where it decreased tumor cell proliferation and reduced tumor volume.

5.2 ATC Code

L02BB05

L - Antineoplastic and immunomodulating agents

L02 - Endocrine therapy

L02B - Hormone antagonists and related agents

L02BB - Anti-androgens

L02BB05 - Apalutamide

5.3 Absorption, Distribution and Excretion

Absorption

Mean absolute oral bioavailability was approximately 100%. Median time to achieve peak plasma concentration (tmax) was 2 hours (range: 1 to 5 hours). Median tmax may be increased with a high-fat meal. Administration of oral apalutamide at recommended dosages resulted in a steady state within 4 weeks with a maximum peak concentration (Cmax) and AUC of 6.0 mcg/mL and 100 mcgh/mL, respectively. Cmax and AUC of apalutamide is expected to increase in a dose-proportional manner. The mean mean peak-to-trough ratio was 1.63 indicating low daily fluctuations in the plasma concentrations of the drug. The major active metabolite N-desmethyl apalutamide Cmax was 5.9 mcg/mL (1.0) and AUC was 124 mcgh/mL (23) at steady-state after the recommended dosage.

Route of Elimination

Apalutamide and its main active metabolite are subject to both renal and focal elimination. Up to 70 days following a single oral administration of radiolabeled apalutamide, 65% of the dose was recovered in urine (1.2% of dose as unchanged apalutamide and 2.7% as N-desmethyl apalutamide) and 24% was recovered in feces (1.5% of dose as unchanged apalutamide and 2% as N-desmethyl apalutamide).

Volume of Distribution

The mean apparent volume of distribution at steady-state of apalutamide was approximately 276 L.

Clearance

The CL/F of apalutamide was 1.3 L/h after single dosing and increased to 2.0 L/h at steady-state after once-daily dosing. An increase in apparent clearance (CL/F) was observed with repeat dosing, likely due to induction of apalutamides own metabolism. The auto-induction effect likely reached its maximum at the recommended dosage because exposure of apalutamide across the dose range of 30 to 480 mg is dose-proportional.

5.4 Metabolism/Metabolites

Apalutamide primarily undergoes CYP2C8 and CYP3A4-mediated metabolism to its pharmacologically active metabolite, N-desmethyl apalutamide. The contribution of CYP2C8 and CYP3A4 in the total metabolism of apalutamide is approximately 58% and and 13% following single dose but changes to 40% and 37%, respectively at steady-state. The auto-induction of CYP3A4-mediated metabolism by apalutamide may explain the increase in CYP3A4 enzymatic activity at steady-state. Based on systemic exposure, relative potency, and pharmacokinetic properties, N-desmethyl apalutamide likely contributed to the clinical activity of apalutamide.

5.5 Biological Half-Life

The mean effective half-life for apalutamide in patients with NM-CRPC was approximately 3 days at steady-state.

5.6 Mechanism of Action

Persistent androgen receptor (AR) signaling is a common feature of castration-resistant prostate cancer (CRPC), attributed to AR gene-amplification, AR gene mutation, increased AR expression or increased androgen biosynthesis in prostate tumors. Apalutamide is an antagonist of AR that to the binding-site in the ligand-binding domain of the receptor with the IC50 of 16 nM. Upon binding, apalutamide disrupts AR signalling, inhibits DNA binding, and impedes AR-mediated gene transcription. Apalutamide impairs the translocation of AR from the cytoplasm to the nucleus thus reduces the concentrations of AR available to interact with the androgen response-elements (AREs). Upon treatment with apalutamide, AR was not recruited to the DNA promoter-regions. Its main metabolite, N-desmethyl apalutamide, is a less potent inhibitor of AR, and exhibited one-third the activity of apalutamide in an in vitro transcriptional reporter assay.

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

USDMF

01

Dr Reddys Laboratories Ltd

India

CPhI WW Frankfurt

Booth #9.1B48

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Contact Supplier

India

Virtual Booth

Digital Content

APALUTAMIDE

GDUFA

DMF Review : Complete

Rev. Date : 2020-10-28

Pay. Date : 2020-09-30

DMF Number : 34667

Submission : 2020-03-24

Status : Active

Type : II

02

Dr Reddys Laboratories Ltd

India

CPhI WW Frankfurt

Booth #9.1B48

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

Contact Supplier

India

Virtual Booth

Digital Content

APALUTAMIDE (AMORPHOUS)

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 35740

Submission : 2021-03-25

Status : Active

Type : II

03

Porton Pharma Solutions Ltd

China

Duphat

Not Confirmed

Porton Pharma Solutions: Value creation via innovation & discovery through technical platforms.

Contact Supplier

China

Virtual Booth

Digital Content

APALUTAMIDE

GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 39029

Submission : 2023-11-02

Status : Active

Type : II

04

Alembic Pharmaceuticals Ltd

India

Duphat

Not Confirmed

05

Aurisco Pharmaceutical Co Ltd

China

Duphat

Not Confirmed

06

Apitoria Pharma Private Ltd

India

Duphat

Not Confirmed

07

Beijing Hope Pharmaceutical Co Ltd

China

India

Duphat

Not Confirmed

Only 10 entries up to this point, click to access all

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

EU WC

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

KDMF

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

NDC API

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

[{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1630002600,"product":"APALUTAMIDE (TAX INVOICE NO:1905215155 D T:31.07.2021)(GROUP:A)","address":"8-3-167\/D\/16, KALYAN NAGAR - I,VENGAL RAO NAGAR","city":"HYDERABAD, A.P.","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"DUBAI","customer":"GULF AGENCY COMPANY ","customerCountry":"UNITED ARAB EMIRATES","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"20198.5","totalValueFC":"3924.4","currency":"USD","unitRateINR":1455300,"date":"27-Aug-2021","totalValueINR":"291060","totalValueInUsd":"3924.4","indian_port":"HYDERABAD AIR","hs_no":"29337990","bill_no":"4176249","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"UNITED ARAB EMIRATES","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"8-3-167\/D\/16, KALYAN NAGAR - I,VENGAL RAO NAGAR, HYDERABAD, A.P.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1658169000,"product":"APALUTAMIDE","address":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD","city":"HYDERABAD","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"TORONTO","customer":"TO THE ORDER OF","customerCountry":"CANADA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"15000","totalValueFC":"73758.2","currency":"USD","unitRateINR":1173000,"date":"19-Jul-2022","totalValueINR":"5865000","totalValueInUsd":"73758.2","indian_port":"HYDERABAD AIR","hs_no":"29337990","bill_no":"2927748","productDescription":"API","marketType":"REGULATED MARKET","country":"CANADA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"MSN HOUSE, PLOT NO. C-24,INDUSTRIAL HYDERABAD, HYDERABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1674066600,"product":"PHARMACEUTICAL RAW MATERIAL -APALUTAMIDE","address":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES","city":"MUMBAI,MAHARASHTRA","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"LAECPHSA","customerCountry":"ARGENTINA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"5800","totalValueFC":"1149.7","currency":"USD","unitRateINR":470000,"date":"19-Jan-2023","totalValueINR":"94000","totalValueInUsd":"1149.7","indian_port":"BOMBAY AIR","hs_no":"29332990","bill_no":"7082209","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1675362600,"product":"APALUTAMIDE","address":"PLOTNO21JAWAHARLAL NEHRU PHARMACIT Y,PARAWADA","city":"VISAKHAPATNAM,ANDHRA PRADESH","supplier":"LAURUS LABS","supplierCountry":"INDIA","foreign_port":"SHEREMETYEVO","customer":"AMEDART LLC","customerCountry":"RUSSIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"38000","totalValueFC":"2857.5","currency":"USD","unitRateINR":2360000,"date":"03-Feb-2023","totalValueINR":"236000","totalValueInUsd":"2857.5","indian_port":"HYDERABAD AIR","hs_no":"29332990","bill_no":"7513341","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"PLOTNO21JAWAHARLAL NEHRU PHARMACIT Y,PARAWADA, VISAKHAPATNAM,ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1681065000,"product":"APALUTAMIDE STEGE-II (US) (100 GMS)","address":"PLOT NO.2, MAITRIVIHAR BEHIND MAITRIVANAM, AMEERPET","city":"HYDERABAD","supplier":"AUROBINDO PHARMA LIMITED","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES, BA","customer":"BIOPROFARMA BAGO S ","customerCountry":"ARGENTINA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"44500","totalValueFC":"4282.9","currency":"USD","unitRateINR":3510000,"date":"10-Apr-2023","totalValueINR":"351000","totalValueInUsd":"4282.9","indian_port":"HYDERABAD AIR","hs_no":"29333919","bill_no":"9182993","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"PLOT NO.2, MAITRIVIHAR BEHIND MAITRIVANAM, AMEERPET, HYDERABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1688063400,"product":"APALUTAMIDE PREMIX 25% (TAX INV MH11600","address":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES","city":"MUMBAI,MAHARASHTRA","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"MOSCOW","customer":"JSPHZ","customerCountry":"RUSSIA","quantity":"4.00","actualQuantity":"4","unit":"KGS","unitRateFc":"412500","totalValueFC":"19903.6","currency":"INR","unitRateINR":409000.00050000002,"date":"30-Jun-2023","totalValueINR":"1636000.002","totalValueInUsd":"19903.6","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"0","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"407\/408 SHARDA CHAMBERS,NEW MARINE LINES, MUMBAI,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1693420200,"product":"APALUTAMIDE","address":"MSN HOUSE PLOT NO. C-24INDUSTRI AL ESTATE SANATH NAGAR","city":"Hyderabad","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"NA","customer":"TO THE ORDER OF","customerCountry":"TAIWAN","quantity":"0.70","actualQuantity":"0.7","unit":"KGS","unitRateFc":"9993","totalValueFC":"6941.4","currency":"USD","unitRateINR":821428.59257142863,"date":"31-Aug-2023","totalValueINR":"575000.0148","totalValueInUsd":"6941.4","indian_port":"HYDERABAD ICD","hs_no":"29337990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"TAIWAN","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD ICD","supplierAddress":"MSN HOUSE PLOT NO. C-24INDUSTRI AL ESTATE SANATH NAGAR, Hyderabad","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1696012200,"product":"APALUTAMIDE IH","address":"HETERO CORPORATE, NO. 7-2-A2,","city":"HYDERABAD","supplier":"HETERO DRUGS","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES, BA","customer":"TO THE ORDER OF","customerCountry":"ARGENTINA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"18000","totalValueFC":"3421.3","currency":"USD","unitRateINR":1420000,"date":"30-Sep-2023","totalValueINR":"284000","totalValueInUsd":"3421.3","indian_port":"Hyderabad Air","hs_no":"29333990","bill_no":"4323160","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"HETERO CORPORATE, NO. 7-2-A2,, HYDERABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701628200,"product":"APALUTAMIDE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"SEOUL - INCHEON INT\\'","customer":"PHARMA SOLUTION COMPANY ","customerCountry":"KOREA, REPUBLIC OF","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"32000","totalValueFC":"1982.1","currency":"USD","unitRateINR":1650000,"date":"04-Dec-2023","totalValueINR":"165000","totalValueInUsd":"1982.1","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"5795264","productDescription":"API","marketType":"REGULATED MARKET","country":"KOREA,REPUBLIC OF","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1708540200,"product":"APALUTAMIDE IH","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"DR. REDDY\\'S LABORATORIES","supplierCountry":"INDIA","foreign_port":"BASEL","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"SWITZERLAND","quantity":"0.12","actualQuantity":"120","unit":"GMS","unitRateFc":"14.6","totalValueFC":"1729.8","currency":"USD","unitRateINR":1196.0666666666666,"date":"22-Feb-2024","totalValueINR":"143528","totalValueInUsd":"1729.8","indian_port":"Reddy r-SEZ\/Srikakulam","hs_no":"29420090","bill_no":"4000136","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Reddy r-SEZ\/Srikakulam","supplierAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE, HYDERABAD ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1710959400,"product":"APALUTAMIDE PREMIX PLACEBO(QTY:150.00GM)(LUT(ARN)NO:AD270323055216A DT:27\/03\/2023)(TAX INV.NO:MH1160000617 DT","address":"407\/408,SHARDA CHAMBERS,","city":"MUMBAI, MAHARASHTRA.","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"MONTEVIDEO -","customer":"PEISRL","customerCountry":"URUGUAY","quantity":"0.15","actualQuantity":"150","unit":"GMS","unitRateFc":"12","totalValueFC":"1752.7","currency":"USD","unitRateINR":970.22860000000003,"date":"21-Mar-2024","totalValueINR":"145534.29","totalValueInUsd":"1752.7","indian_port":"Bombay Air","hs_no":"29420090","bill_no":"8504881","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"URUGAY","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"407\/408,SHARDA CHAMBERS,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713119400,"product":"APALUTAMIDE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"GENVEON LLACSANAYI VE TICARET A.S.","customerCountry":"TURKEY","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"10000","totalValueFC":"1978.3","currency":"USD","unitRateINR":826000,"date":"15-Apr-2024","totalValueINR":"165200","totalValueInUsd":"1978.3","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"9139831","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713724200,"product":"APALUTAMIDE N LAUR PW UD US B\/N-C008271022 MFG B\/N- B667781","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"SANDOZ B2B","supplierCountry":"INDIA","foreign_port":"LJUBLJANA - BRNIK","customer":"UROS BUZETI","customerCountry":"SLOVENIA","quantity":"0.98","actualQuantity":"0.978","unit":"KGS","unitRateFc":"10508.7","totalValueFC":"9126.7","currency":"USD","unitRateINR":779292.75051124755,"date":"22-Apr-2024","totalValueINR":"762148.31","totalValueInUsd":"9126.7","indian_port":"Bombay Air","hs_no":"29332990","bill_no":"9294969","productDescription":"API","marketType":"REGULATED MARKET","country":"SLOVENIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"SANDOZ HOUSE, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713724200,"product":"APALUTAMIDE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"OSAKA","customer":"TOWA PHARMACEUTICAL","customerCountry":"JAPAN","quantity":"5.60","actualQuantity":"5.6","unit":"KGS","unitRateFc":"15000","totalValueFC":"83187.9","currency":"USD","unitRateINR":1240500,"date":"22-Apr-2024","totalValueINR":"6946800","totalValueInUsd":"83187.9","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"9311897","productDescription":"API","marketType":"REGULATED MARKET","country":"JAPAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715711400,"product":"APALUTAMIDE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"MIAMI, FL","customer":"ACTAVIS INC","customerCountry":"UNITED STATES","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"6000","totalValueFC":"5945.7","currency":"USD","unitRateINR":495600,"date":"15-May-2024","totalValueINR":"495600","totalValueInUsd":"5945.7","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"9893867","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1715711400,"product":"APALUTAMIDE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"MIAMI, FL","customer":"ACTAVIS INC","customerCountry":"UNITED STATES","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"6000","totalValueFC":"5945.7","currency":"USD","unitRateINR":495600,"date":"15-May-2024","totalValueINR":"495600","totalValueInUsd":"5945.7","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"9894732","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717093800,"product":"APALUTAMIDE WS SAMPLE 100 GM (TAX INV# MH2411600102 DT:31.05.2024)","address":"407\/408,SHARDA CHAMBERS,","city":"MUMBAI, MAHARASHTRA.","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"SINGAPORE","customer":"IWLOG","customerCountry":"SINGAPORE","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"17.5","totalValueFC":"1725","currency":"USD","unitRateINR":1437.8466000000001,"date":"31-May-2024","totalValueINR":"143784.66","totalValueInUsd":"1725","indian_port":"Bombay Air","hs_no":"29332990","bill_no":"1341840","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SINGAPORE","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"407\/408,SHARDA CHAMBERS,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717525800,"product":"APALUTAMIDE API (SAMPLE PACKED INTO 2 PE BAGS& PE BAGS INSERTED IN SEALED ALUMINUM BAG.) B\/N- 40006644","address":"SANDOZ HOUSE","city":"MUMBAI ,MAHARASHTRA","supplier":"SANDOZ B2B","supplierCountry":"INDIA","foreign_port":"LJUBLJANA - BRNIK","customer":"PIJA KOSIR (ANALYTICS, STABILITY)","customerCountry":"SLOVENIA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"10508.7","totalValueFC":"933","currency":"USD","unitRateINR":778822.29999999993,"date":"05-Jun-2024","totalValueINR":"77882.23","totalValueInUsd":"933","indian_port":"Bombay Air","hs_no":"29332990","bill_no":"1450779","productDescription":"API","marketType":"REGULATED MARKET","country":"SLOVENIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"SANDOZ HOUSE, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1718735400,"product":"APALUTAMIDE","address":"Floor No.22, Plot No.1, Survey No.83\/1, Galaxy Tower","city":"Hyderabad","supplier":"APITORIA PHARMA PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES, BA","customer":"BIOPROFARMA BAGO S.A","customerCountry":"ARGENTINA","quantity":"1.40","actualQuantity":"1.4","unit":"KGS","unitRateFc":"44000","totalValueFC":"60777.1","currency":"USD","unitRateINR":3624028.5714285718,"date":"19-Jun-2024","totalValueINR":"5073640","totalValueInUsd":"60777.1","indian_port":"Hyderabad Air","hs_no":"29333990","bill_no":"1784559","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"Floor No.22, Plot No.1, Survey No.83\/1, Galaxy Tower, Hyderabad","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725042600,"product":"APALUTAMIDE 25% SPRAY DRY FORM (OTHER) (TAX INV# MH2411600256 DT: 31.08.2024)","address":"407\/408,SHARDA CHAMBERS,","city":"MUMBAI, MAHARASHTRA.","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"LABECPHSA","customerCountry":"ARGENTINA","quantity":"7.80","actualQuantity":"7.8","unit":"KGS","unitRateFc":"5500","totalValueFC":"42331.6","currency":"USD","unitRateINR":455219.99487179489,"date":"31-Aug-2024","totalValueINR":"3550715.96","totalValueInUsd":"42331.6","indian_port":"Bombay Air","hs_no":"29332990","bill_no":"3661784","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"407\/408,SHARDA CHAMBERS,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725042600,"product":"APALUTAMIDE WS SAMPLE 100 GM (TAX INV# MH2411600256 DT: 31.08.2024)","address":"407\/408,SHARDA CHAMBERS,","city":"MUMBAI, MAHARASHTRA.","supplier":"BDR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"BUENOS AIRES","customer":"LABECPHSA","customerCountry":"ARGENTINA","quantity":"0.10","actualQuantity":"100","unit":"GMS","unitRateFc":"17.5","totalValueFC":"1722.9","currency":"USD","unitRateINR":1445.1178,"date":"31-Aug-2024","totalValueINR":"144511.78","totalValueInUsd":"1722.9","indian_port":"Bombay Air","hs_no":"29332990","bill_no":"3661784","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ARGENTINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"407\/408,SHARDA CHAMBERS,, MUMBAI, MAHARASHTRA.","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725820200,"product":"APALUTAMIDE IH","address":"HETERO HOUSE,H.NO.8-3-166\/7\/1ERRAGADDA","city":"HYDERABAD","supplier":"HETERO DRUGS","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"DEVA HOLDING AS","customerCountry":"TURKEY","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"11000","totalValueFC":"32524.9","currency":"USD","unitRateINR":908540.83999999997,"date":"09-Sep-2024","totalValueINR":"2725622.52","totalValueInUsd":"32524.9","indian_port":"Hyderabad Air","hs_no":"29333990","bill_no":"3872619","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"HETERO HOUSE,H.NO.8-3-166\/7\/1ERRAGADDA, HYDERABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725906600,"product":"APALUTAMIDE API","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"ZYDUS LIFESCIENCES LIMITED","supplierCountry":"INDIA","foreign_port":"ZURICH","customer":"MICRO-SPHERE","customerCountry":"SWITZERLAND","quantity":"7.00","actualQuantity":"7","unit":"KGS","unitRateFc":"11759.9","totalValueFC":"81679.9","currency":"USD","unitRateINR":977839.14285714284,"date":"10-Sep-2024","totalValueINR":"6844874","totalValueInUsd":"81679.9","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29420090","bill_no":"4004322","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad-ZIPL-SEZ","supplierAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H, AHMEDABAD,GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725906600,"product":"APALUTAMIDE API","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"ZYDUS LIFESCIENCES LIMITED","supplierCountry":"INDIA","foreign_port":"ZURICH","customer":"MICRO-SPHERE","customerCountry":"SWITZERLAND","quantity":"36.00","actualQuantity":"36","unit":"KGS","unitRateFc":"17927.2","totalValueFC":"640364.2","currency":"USD","unitRateINR":1490647.3055555555,"date":"10-Sep-2024","totalValueINR":"53663303","totalValueInUsd":"640364.2","indian_port":"Ahmedabad-ZIPL-SEZ","hs_no":"29420090","bill_no":"4004322","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad-ZIPL-SEZ","supplierAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H, AHMEDABAD,GUJARAT","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732645800,"product":"APALUTAMIDE IH","address":"HETERO CORPORATE, NO. 7-2-A2,","city":"HYDERABAD","supplier":"HETERO DRUGS","supplierCountry":"INDIA","foreign_port":"ISTANBUL","customer":"ABDI IBRAHIM","customerCountry":"TURKEY","quantity":"0.90","actualQuantity":"0.9","unit":"KGS","unitRateFc":"10000","totalValueFC":"8806.2","currency":"USD","unitRateINR":825714.74444444443,"date":"27-Nov-2024","totalValueINR":"743143.27","totalValueInUsd":"8806.2","indian_port":"Hyderabad Air","hs_no":"29333990","bill_no":"5941588","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"TURKEY","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"HETERO CORPORATE, NO. 7-2-A2,, HYDERABAD","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1732645800,"product":"APALUTAMIDE","address":"MSN HOUSE, PLOT NO. C-24,","city":"HYDERABAD. AP","supplier":"MSN LABORATORIES","supplierCountry":"INDIA","foreign_port":"SHEREMETYEVO","customer":"NANOPHARMA DEVELOPMENT LLC","customerCountry":"RUSSIA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"50000","totalValueFC":"9069.6","currency":"USD","unitRateINR":3826830.3999999994,"date":"27-Nov-2024","totalValueINR":"765366.08","totalValueInUsd":"9069.6","indian_port":"Hyderabad Air","hs_no":"29337990","bill_no":"5948651","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"RUSSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"MSN HOUSE, PLOT NO. C-24,, HYDERABAD. AP","customerAddress":""},{"dataSource":"API Import","activeIngredients":"APALUTAMIDE","year":"2021","qtr":"Q1","strtotime":1611081000,"product":"(N.C.V) APALUTAMIDE JNJ-56021927-AAA,R601592 POWDER 1BOTTLE=350G (FOR R&D UNIT ONLY)","address":"30 FORJETT STREETPOST BOX NO 9301","city":"MUMBAI, MAHARASHTRA.","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"BRUSSELS","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.35","actualQuantity":"350","unit":"GMS","unitRateFc":"2.5","totalValueFC":"1089.5","currency":"EUR","unitRateINR":"227.7","date":"20-Jan-2021","totalValueINR":"79682.4","totalValueInUsd":"1089.5","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"2433436","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"","customerAddress":"30 FORJETT STREETPOST BOX NO 9301"},{"dataSource":"API Import","activeIngredients":"APALUTAMIDE","year":"2021","qtr":"Q1","strtotime":1615314600,"product":"(N.C.V) APALUTAMIDE 250MG SPRAY DRIED POWDER (FOR TESTING PURPOSE ONLY)","address":"30 FORJETT STREETPOST BOX NO 9301","city":"MUMBAI, MAHARASHTRA.","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"BRUSSELS","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.08","actualQuantity":"75.48","unit":"GMS","unitRateFc":"2.5","totalValueFC":"230.5","currency":"EUR","unitRateINR":"222.3","date":"10-Mar-2021","totalValueINR":"16781.59","totalValueInUsd":"230.5","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"3091647","productDescription":"API","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"","customerAddress":"30 FORJETT STREETPOST BOX NO 9301"},{"dataSource":"API Import","activeIngredients":"APALUTAMIDE","year":"2021","qtr":"Q2","strtotime":1620066600,"product":"(N.C.V) INTERMEDIATE OF APALUTAMIDE (JNJ-63632335-AAA,T003671) (FOR R&D UNIT ONLY)","address":"30 FORJETT STREETPOST BOX NO 9301","city":"MUMBAI, MAHARASHTRA.","supplier":"JOHNSON & JOHNSON","supplierCountry":"BELGIUM","foreign_port":"BRUSSELS","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.3","unit":"GMS","unitRateFc":"286","totalValueFC":"107.5","currency":"EUR","unitRateINR":"26240.5","date":"04-May-2021","totalValueINR":"7872.15","totalValueInUsd":"107.5","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"3812193","productDescription":"Intermediate","marketType":"REGULATED MARKET","country":"BELGIUM","selfForZScoreResived":"Pharma Grade","supplierPort":"BRUSSELS","supplierAddress":"","customerAddress":"30 FORJETT STREETPOST BOX NO 9301"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1626201000,"product":"(N.C.V) APALUTAMIDE API JNJ-56021927-AAA (FOR TESTING PURPOSE ONLY)","address":"30 FORJETT STREETPOST BOX NO 9301","city":"MUMBAI, MAHARASHTRA.","supplier":"JOHNSON & JOHNSON INNOVATIVE MEDICINE","supplierCountry":"UNITED STATES","foreign_port":"","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.25","actualQuantity":"250","unit":"GMS","unitRateFc":"7.4","totalValueFC":"1859.1","currency":"USD","unitRateINR":"554.2","date":"14-Jul-2021","totalValueINR":"138549.74","totalValueInUsd":"1859.1","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"4670417","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"","supplierAddress":"","customerAddress":"30 FORJETT STREETPOST BOX NO 9301"},{"dataSource":"API Import","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1638729000,"product":"(N.C.V) APALUTAMIDE API JNJ-56021927-AAA (FOR TESTING PURPOSE ONLY)","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JANSSEN PHARMACEUTICALS INC.","supplierCountry":"UNITED STATES","foreign_port":"N\/A","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.25","actualQuantity":"250","unit":"GMS","unitRateFc":"7.4","totalValueFC":"1851.5","currency":"USD","unitRateINR":"558.6","date":"06-Dec-2021","totalValueINR":"139653.72","totalValueInUsd":"1851.5","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"6555205","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1674153000,"product":"(N.C.V) JNJ-56021927-AAA R601592 REF STD OF APALUTAMIDE BENZAMIDE 4-[7-(6-CYANO-5-(TRIFLUOROMETHYL)-3-PYRIDINYL]-8-OXO-6","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JOHNSON & JOHNSON","supplierCountry":"SWITZERLAND","foreign_port":"NA","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.01","actualQuantity":"6","unit":"GMS","unitRateFc":"286","totalValueFC":"1877.4","currency":"EUR","unitRateINR":"25582.7","date":"20-Jan-2023","totalValueINR":"153496.2","totalValueInUsd":"1877.4","indian_port":"BOMBAY AIR","hs_no":"29333990","bill_no":"4272733","productDescription":"API","marketType":"REGULATED MARKET","country":"SWITZERLAND","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1674412200,"product":"APALUTAMIDE","address":"H.NO. 8-2-337, BESIDE TV9 OFFICE, ROAD NO.3, BANJARA HILLS, Contact N","city":"HYDERABAD","supplier":"HONG KONG AURISCO TRADING CO.,LIMITED","supplierCountry":"CHINA","foreign_port":"NA","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"1.50","actualQuantity":"1.5","unit":"KGS","unitRateFc":"12000","totalValueFC":"18119","currency":"USD","unitRateINR":"987600","date":"23-Jan-2023","totalValueINR":"1481400","totalValueInUsd":"18119","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"4316689","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"H.NO. 8-2-337, BESIDE TV9 OFFICE, ROAD NO.3, BANJARA HILLS, Contact N"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1688149800,"product":"(N.C.V) APALUTAMIDE API JNJ-56021927-AAA (FOR TESTING PURPOSE ONLY)","address":"L.B.S. MARG,,MULUND-WEST","city":"MUMBAI,MAHARASHTRA","supplier":"JANSSEN PHARMACEUTICA INC","supplierCountry":"UNITED STATES","foreign_port":"NA","customer":"JOHNSON & JOHNSON","customerCountry":"INDIA","quantity":"0.29","actualQuantity":"290","unit":"GMS","unitRateFc":"6.8","totalValueFC":"1997.7","currency":"USD","unitRateINR":"566.4","date":"01-Jul-2023","totalValueINR":"164187.632","totalValueInUsd":"1997.7","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"L.B.S. MARG,,MULUND-WEST"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1699554600,"product":"APALUTAMIDE (IH)","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"HONG KONG AURISCO TRADING CO.,LIMITED","supplierCountry":"CHINA","foreign_port":"SHANGHAI - PU DONG","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"32.00","actualQuantity":"32","unit":"KGS","unitRateFc":"12000","totalValueFC":"388054","currency":"USD","unitRateINR":"1009800","date":"10-Nov-2023","totalValueINR":"32313600","totalValueInUsd":"388054","indian_port":"Hyderabad Air","hs_no":"29339990","bill_no":"8722820","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"SHANGHAI - PU DONG","supplierAddress":"RM D 10\/F TOWER A BILLION CTR 1 WANG KWONG RD KOWLOON BAY KL,SDNF Hong Kong","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1723055400,"product":"APALUTAMIDE (956104-40-8) (INV NO. ST20240707\/ST20240718-3\/ST20240707-2\/ST20240718-1)","address":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ","city":"AMRITSAR,PUNJAB","supplier":"M\/S. QUANZHOU FORTUNE BIOPHARMA CO.LTD","supplierCountry":"CHINA","foreign_port":"BEIJING","customer":"KWALITY PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"4000","totalValueFC":"8068.8","currency":"USD","unitRateINR":"338400","date":"08-Aug-2024","totalValueINR":"676800","totalValueInUsd":"8068.8","indian_port":"Delhi Air","hs_no":"29339990","bill_no":"4936661","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BEIJING","supplierAddress":"ADD:ROOM 2603 RONG TAI\\'AN BUILDINGNO.139 JINHUAI STREET FENGZE ROADFENGZE DISTRICT QUANZHOU CITY FUJIA CHINA","customerAddress":"VILLAGE NAG KALAN,MAJITHA ROAD,MAJ"}]

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

Upgrade, download data, analyse, strategize, subscribe with us contact

Drugs in Development

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

INTERMEDIATES SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDF Dossiers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDA Orange Book

01

JANSSEN BIOTECH

Duphat

Not Confirmed

02

JANSSEN INC

U.S.A

Janssen Pharmaceutica (Pty) Ltd

U.S.A

Duphat

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Dossiers

01

XYZ Pharma

Gabon

Duphat

Not Confirmed

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Related Excipient Companies

Upload your portfolio for free, ask us

Excipients by Applications

Click here to find the perfect excipient manufacturers by their capabilities

Fillers, Diluents & Binders

Coating Systems & Additives

Thickeners and Stabilizers

Disintegrants & Superdisintegrants

Direct Compression

Controlled & Modified Release

Lubricants & Glidants

Topical

Co-Processed Excipients

Granulation

Film Formers & Plasticizers

Solubilizers

Coloring Agents

Emulsifying Agents

Parenteral

Taste Masking

Rheology Modifiers

Chewable & Orodispersible Aids

API Stability Enhancers

01

Gangwal Chemicals

India

Pharmatech Expo 2025

Not Confirmed

02

Ideal Cures Pvt Ltd

India

Pharmatech Expo 2025

Not Confirmed

Digital Content

Create Content with PharmaCompass, ask us

DATA COMPILATION #PharmaFlow

NEWS #PharmaBuzz

J&J's Erleada shows survival edge over Xtandi in real-world study

02 Oct 2024

// FIERCE PHARMA

ORIC Pharmaceuticals Reports Q2 2024 Results And Operational Updates

12 Aug 2024

// GLOBENEWSWIRE

Johnson & Johnson 1Q Results

20 May 2024

// CONTRACT PHARMA

ERLEADA® Combo Shows 100% Biochemical Control Post-Prostatectomy

03 May 2024

// PR NEWSWIRE

Kairos Pharma Doses First Patient in Phase 2 Trial of Lead Drug Candidate ENV105

30 Jan 2024

// GLOBENEWSWIRE

Erleada Approved as the Only Androgen Receptor Inhibitor in Canada

10 Aug 2023

// NEWSWIRE

Global Sales Information

Do you need Business Intel? Ask us

US Medicaid Prescriptions

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Finished Drug Prices

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Annual Reports

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Market Place

Do you need sourcing support? Ask us

APIs

Apalutamide (1 kg) API needed in India [ENA21562]

A company that focuses on the research, development and manufacturing of OSDs, injectables, liquids & semi-solids is looking for suppliers of Apalutamide (1 kg) API for development purposes. The suppliers must support this enquiry with CoA.

26 Dec 2024

Various APIs needed in Brazil [ENA12413]

A company that deals in the research, development & trading of health products is looking for suppliers of Various APIs for commercial purpose. The required quantity is MOQ for each. The suppliers must support this enquiry with ANVISA, DMF, PIC/s GMP & CoA. 1. Osimertinib API 2. Ruxolitinib API 3. Apalutamide API 4. Pembrolizumab API

14 Jan 2022

Various APIs needed in Brazil [ENA12002]

A large pharmaceutical manufacturing company that deals in portfolios like dermatological, cardiological, gynecological, gastric, oncology, respiratory & CNS is looking for suppliers of Various APIs for a new project. The suppliers must support this enquiry with USFDA, DMF, GMP & CoA. 1. EP/ BP/ USP Grade Apalutamide API 2. EP/ BP/ USP Grade Ruxolitinib Phosphate API

03 Dec 2021

Apalutamide API needed in India [ENA03003]

A multinational pharmaceutical company headquartered in Mumbai is looking for suppliers of Apalutamide API for domestic consumption.

20 Dec 2018

Apalutamide, Cabozantinib malate and other APIs needed in Bangladesh [ENA02773]

M.R Trading Corporation, Bangladesh is looking for suppliers of following APIs: 1. Apalutamide 2. Cabozantinib malate 3. Ruxolitinib Phosphate 4. Trabectedin INN 5. Venetoclax 6. Aflibercept Interested suppliers can contact Masud via Mob: +880 01725219963 or Email: info@mrtcbd.com.

28 Nov 2018

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

FDF DOSSIERS

APALUTAMIDE

BIO Partnering at JPM

Not Confirmed

Only 10 entries up to this point, click to access all

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

ABOUT THIS PAGE

Apalutamide Manufacturers

A Apalutamide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Apalutamide, including repackagers and relabelers. The FDA regulates Apalutamide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Apalutamide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Apalutamide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Apalutamide Suppliers

A Apalutamide supplier is an individual or a company that provides Apalutamide active pharmaceutical ingredient (API) or Apalutamide finished formulations upon request. The Apalutamide suppliers may include Apalutamide API manufacturers, exporters, distributors and traders.

click here to find a list of Apalutamide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Apalutamide USDMF

A Apalutamide DMF (Drug Master File) is a document detailing the whole manufacturing process of Apalutamide active pharmaceutical ingredient (API) in detail. Different forms of Apalutamide DMFs exist exist since differing nations have different regulations, such as Apalutamide USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Apalutamide DMF submitted to regulatory agencies in the US is known as a USDMF. Apalutamide USDMF includes data on Apalutamide's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Apalutamide USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Apalutamide suppliers with USDMF on PharmaCompass.

Apalutamide KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Apalutamide Drug Master File in Korea (Apalutamide KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Apalutamide. The MFDS reviews the Apalutamide KDMF as part of the drug registration process and uses the information provided in the Apalutamide KDMF to evaluate the safety and efficacy of the drug.

After submitting a Apalutamide KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Apalutamide API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Apalutamide suppliers with KDMF on PharmaCompass.

Apalutamide WC

A Apalutamide written confirmation (Apalutamide WC) is an official document issued by a regulatory agency to a Apalutamide manufacturer, verifying that the manufacturing facility of a Apalutamide active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Apalutamide APIs or Apalutamide finished pharmaceutical products to another nation, regulatory agencies frequently require a Apalutamide WC (written confirmation) as part of the regulatory process.

click here to find a list of Apalutamide suppliers with Written Confirmation (WC) on PharmaCompass.

Apalutamide NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Apalutamide as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Apalutamide API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Apalutamide as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Apalutamide and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Apalutamide NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Apalutamide suppliers with NDC on PharmaCompass.

Apalutamide GMP

Apalutamide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Apalutamide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Apalutamide GMP manufacturer or Apalutamide GMP API supplier for your needs.

Apalutamide CoA

A Apalutamide CoA (Certificate of Analysis) is a formal document that attests to Apalutamide's compliance with Apalutamide specifications and serves as a tool for batch-level quality control.

Apalutamide CoA mostly includes findings from lab analyses of a specific batch. For each Apalutamide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Apalutamide may be tested according to a variety of international standards, such as European Pharmacopoeia (Apalutamide EP), Apalutamide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Apalutamide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.

Market Place

Home

Post Enquiry

Market Place

Find Apalutamide manufacturers, exporters & distributors on PharmaCompass

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

26 API Suppliers

11 USDMF

4 EU WC

1 KDMF

8 NDC API

21 Listed Suppliers

$ API Reference Price

DEVELOPMENTS

17 Drugs in Development

INTERMEDIATES

17 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

10 FDF Dossiers

2 FDA Orange Book

2 Europe

2 Canada

2 Australia

1 South Africa

1 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 SPI Pharma

2 Seqens

4 DKSH

2 Faran Shimi Pharmaceutical

7 Gangwal Healthcare

3 Actylis

1 Aeon Procare

5 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

9 BASF

5 Corel Pharma Chem

3 DFE Pharma

1 Finar

7 Gangwal Chemicals

3 Ideal Cures Pvt Ltd

1 Ingredion Pharma Solutions

6 Kerry

7 Microlex e.U

2 Nomisma Healthcare

1 Novo Excipients

1 Pharmatrans-Sanaq

2 Pluviaendo

3 Prachin Chemical

10 Roquette

3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

10 Sigachi Industries

3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

22 Fillers, Diluents & Binders

20 Coating Systems & Additives

15 Thickeners and Stabilizers

15 Disintegrants & Superdisintegrants

14 Direct Compression

13 Controlled & Modified Release

13 Lubricants & Glidants

8 Topical

8 Co-Processed Excipients

8 Granulation

4 Film Formers & Plasticizers

4 Solubilizers

3 Coloring Agents

3 Emulsifying Agents

3 Parenteral

3 Taste Masking

2 Rheology Modifiers

2 Chewable & Orodispersible Aids

2 API Stability Enhancers

DIGITAL CONTENT

3 DATA COMPILATION #PharmaFlow

52 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

2 Finished Drug Prices

4 Annual Reports

MARKET PLACE