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Synopsis

Synopsis

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Chemistry

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Also known as: 26544-34-3, Apigenin-7-apioglucoside, Apioside, 6qu3eze37u, Chebi:15932, Apigenin 7-o-[beta-d-apiosyl-(1->2)-beta-d-glucoside]
Molecular Formula
C26H28O14
Molecular Weight
564.5  g/mol
InChI Key
NTDLXWMIWOECHG-YRCFQSNFSA-N
FDA UNII
6QU3EZE37U

Apiin
apiin is a natural product found in Crotalaria micans, Limonium axillare, and other organisms with data available.
1 2D Structure

Apiin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
7-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
2.1.2 InChI
InChI=1S/C26H28O14/c27-8-18-20(32)21(33)22(40-25-23(34)26(35,9-28)10-36-25)24(39-18)37-13-5-14(30)19-15(31)7-16(38-17(19)6-13)11-1-3-12(29)4-2-11/h1-7,18,20-25,27-30,32-35H,8-10H2/t18-,20-,21+,22-,23+,24-,25+,26-/m1/s1
2.1.3 InChI Key
NTDLXWMIWOECHG-YRCFQSNFSA-N
2.1.4 Canonical SMILES
C1C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)O)O)CO)O)O)O)(CO)O
2.1.5 Isomeric SMILES
C1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H](O[C@H]2OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)O)O)CO)O)O)O)(CO)O
2.2 Other Identifiers
2.2.1 UNII
6QU3EZE37U
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 6''-acetylapiin

2.3.2 Depositor-Supplied Synonyms

1. 26544-34-3

2. Apigenin-7-apioglucoside

3. Apioside

4. 6qu3eze37u

5. Chebi:15932

6. Apigenin 7-o-[beta-d-apiosyl-(1->2)-beta-d-glucoside]

7. 7-(((2s,3r,4s,5s,6r)-3-(((2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4h-chromen-4-one

8. 7-((2-o-beta-d-apiofuranosyl-beta-d-glucopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyranone

9. 7-[(2s,3r,4s,5s,6r)-3-[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one

10. 5,7,4'-trihydroxyflavone 7-o-[beta-d-apiosyl-(1->2)-beta-d-glucoside]

11. 7-o-(beta-d-apiofuranosyl-1,2-beta-d-glucosyl)-5,7,4'-trihydroxyflavone

12. 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4h-chromen-7-yl 2-o-[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl]-beta-d-glucopyranoside

13. 5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4h-chromen-7-yl 3-c-(hydroxymethyl)-beta-d-glycero-tetrofuranosyl-(1->2)-beta-d-glucopyranoside

14. 7-[(2-o-d-apio-beta-d-furanosyl-beta-d-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxy-phenyl)-4h-1-benzopyran-4-one

15. Unii-6qu3eze37u

16. Einecs 247-780-0

17. Spectrum_000204

18. Specplus_000939

19. Apiin (11)

20. Spectrum2_001800

21. Spectrum3_001787

22. Spectrum4_001817

23. Spectrum5_000553

24. Apiin [mi]

25. Bspbio_003313

26. Kbiogr_002458

27. Kbioss_000684

28. Spectrum350025

29. Mls000575008

30. Divk1c_007035

31. Schembl316910

32. Spbio_001759

33. Chembl1535342

34. Kbio1_001979

35. Kbio2_000684

36. Kbio2_003252

37. Kbio2_005820

38. Kbio3_002815

39. Dtxsid90949393

40. Bdbm153268

41. Hms2209p05

42. Hy-n0577

43. Zinc3983878

44. Ccg-39950

45. Mfcd30749827

46. Akos030632988

47. Sdccgmls-0066949.p001

48. Ncgc00178147-01

49. As-74876

50. Smr000156232

51. Cs-0009113

52. N2161

53. C04858

54. Sr-01000712126

55. Q2858300

56. Sr-01000712126-2

57. Brd-k52379519-001-02-0

58. 4h-1-benzopyran-4-one, 7-[(2-o-d-apio-beta-d-furanosyl-beta-d-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)-

59. 7-((2-o-.beta.-d-apiofuranosyl-.beta.-d-glucopyranosyl)oxy)-5- Hydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyranone

60. 7-((2-o-d-apio-.beta.-d-furanosyl-.beta.-d-glucopyranosyl)oxy)- 5-hydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

61. 7-((2-o-d-apio-beta-d-furanosyl-beta-d-glucopyranosyl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

62. 7-{[(2s,3r,4s,5s,6r)-3-{[(2s,3r,4r)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy}-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-hydroxy-2-(4-hydroxyphenyl)-4h-chromen-4-one

2.4 Create Date
2004-09-16
3 Chemical and Physical Properties
Molecular Weight 564.5 g/mol
Molecular Formula C26H28O14
XLogP3-0.4
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count14
Rotatable Bond Count7
Exact Mass564.14790556 g/mol
Monoisotopic Mass564.14790556 g/mol
Topological Polar Surface Area225 Ų
Heavy Atom Count40
Formal Charge0
Complexity923
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

Apiin Manufacturers

A Apiin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Apiin, including repackagers and relabelers. The FDA regulates Apiin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Apiin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Apiin Suppliers

A Apiin supplier is an individual or a company that provides Apiin active pharmaceutical ingredient (API) or Apiin finished formulations upon request. The Apiin suppliers may include Apiin API manufacturers, exporters, distributors and traders.

Apiin GMP

Apiin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Apiin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Apiin GMP manufacturer or Apiin GMP API supplier for your needs.

Apiin CoA

A Apiin CoA (Certificate of Analysis) is a formal document that attests to Apiin's compliance with Apiin specifications and serves as a tool for batch-level quality control.

Apiin CoA mostly includes findings from lab analyses of a specific batch. For each Apiin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Apiin may be tested according to a variety of international standards, such as European Pharmacopoeia (Apiin EP), Apiin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Apiin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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