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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 782487-28-9, Aqx-1125, Aqx-1125 free base, Rosiptor [usan], (1s,3s,4r)-4-[(3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methylidene-3,3a,4,5,6,7-hexahydro-2h-inden-5-yl]-3-(hydroxymethyl)-4-methylcyclohexan-1-ol, 6r5034f862
Molecular Formula
C20H35NO2
Molecular Weight
321.5  g/mol
InChI Key
MDEJTPWQNNMAQF-BVMLLJBZSA-N
FDA UNII
6R5034F862

AQX-1125
AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.
1 2D Structure

AQX-1125

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(1S,3S,4R)-4-[(3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-methylidene-3,3a,4,5,6,7-hexahydro-2H-inden-5-yl]-3-(hydroxymethyl)-4-methylcyclohexan-1-ol
2.1.2 InChI
InChI=1S/C20H35NO2/c1-13-4-5-17-16(11-21)18(7-9-19(13,17)2)20(3)8-6-15(23)10-14(20)12-22/h14-18,22-23H,1,4-12,21H2,2-3H3/t14-,15+,16+,17+,18+,19-,20+/m1/s1
2.1.3 InChI Key
MDEJTPWQNNMAQF-BVMLLJBZSA-N
2.1.4 Canonical SMILES
CC1(CCC(CC1CO)O)C2CCC3(C(C2CN)CCC3=C)C
2.1.5 Isomeric SMILES
C[C@@]1(CC[C@@H](C[C@@H]1CO)O)[C@H]2CC[C@]3([C@H]([C@@H]2CN)CCC3=C)C
2.2 Other Identifiers
2.2.1 UNII
6R5034F862
2.3 Synonyms
2.3.1 MeSH Synonyms

1. (1s,3s,4r)-4-((3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methylidene-octahydro-1h-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol Acetic Acid Salt

2. 4-(4-(aminomethyl)-7a-methyl-1-methylideneoctahydro-1h-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol

3. Aqx-1125

2.3.2 Depositor-Supplied Synonyms

1. 782487-28-9

2. Aqx-1125

3. Aqx-1125 Free Base

4. Rosiptor [usan]

5. (1s,3s,4r)-4-[(3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methylidene-3,3a,4,5,6,7-hexahydro-2h-inden-5-yl]-3-(hydroxymethyl)-4-methylcyclohexan-1-ol

6. 6r5034f862

7. Unii-6r5034f862

8. Rosiptor (usan/inn)

9. Rosiptor [inn]

10. Rosiptor [who-dd]

11. Gtpl9249

12. Chembl3989954

13. Schembl16055992

14. Aqx1125

15. Aqx 1125

16. Aqx-1125aqx-1125

17. Db13012

18. Ac-30923

19. Hy-109011

20. Cs-0030509

21. D11275

22. A902928

23. Q27074488

24. 7-amino-17-methylidene-6,7-seco-5.alpha.-androstane-3.beta.,6-diol

25. (1s,3s,4r)-4-((3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1- Methyleneoctahydro -1h - Inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol

26. (1s,3s,4r)-4-((3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1h-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexanol

27. Cyclohexanemethanol, 2-((3as,4r,5s,7as)-4-(aminomethyl)octahydro-7a-methyl-1-methylene-1h-inden-5-yl)-5-hydroxy-2-methyl-, (1s,2r,5s)-

28. Rosiptor; Aqx-1125; Aqx 1125; Aqx1125;(1s,3s,4r)-4-((3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methyleneoctahydro-1h-inden-5-yl)-3-(hydroxymethyl)-4-methylcyclohexan-1-ol

2.4 Create Date
2014-08-25
3 Chemical and Physical Properties
Molecular Weight 321.5 g/mol
Molecular Formula C20H35NO2
XLogP33
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass321.266779359 g/mol
Monoisotopic Mass321.266779359 g/mol
Topological Polar Surface Area66.5 Ų
Heavy Atom Count23
Formal Charge0
Complexity465
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Looking for 782487-28-9 / AQX-1125 API manufacturers, exporters & distributors?

AQX-1125 manufacturers, exporters & distributors 1

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PharmaCompass offers a list of AQX-1125 API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right AQX-1125 manufacturer or AQX-1125 supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred AQX-1125 manufacturer or AQX-1125 supplier.

PharmaCompass also assists you with knowing the AQX-1125 API Price utilized in the formulation of products. AQX-1125 API Price is not always fixed or binding as the AQX-1125 Price is obtained through a variety of data sources. The AQX-1125 Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

AQX-1125

Synonyms

782487-28-9, Aqx-1125 free base, Rosiptor [usan], (1s,3s,4r)-4-[(3as,4r,5s,7as)-4-(aminomethyl)-7a-methyl-1-methylidene-3,3a,4,5,6,7-hexahydro-2h-inden-5-yl]-3-(hydroxymethyl)-4-methylcyclohexan-1-ol, 6r5034f862, Unii-6r5034f862

Cas Number

782487-28-9

Unique Ingredient Identifier (UNII)

6R5034F862

About AQX-1125

AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.

AQX 1125 Manufacturers

A AQX 1125 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of AQX 1125, including repackagers and relabelers. The FDA regulates AQX 1125 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. AQX 1125 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

AQX 1125 Suppliers

A AQX 1125 supplier is an individual or a company that provides AQX 1125 active pharmaceutical ingredient (API) or AQX 1125 finished formulations upon request. The AQX 1125 suppliers may include AQX 1125 API manufacturers, exporters, distributors and traders.

AQX 1125 GMP

AQX 1125 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of AQX 1125 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right AQX 1125 GMP manufacturer or AQX 1125 GMP API supplier for your needs.

AQX 1125 CoA

A AQX 1125 CoA (Certificate of Analysis) is a formal document that attests to AQX 1125's compliance with AQX 1125 specifications and serves as a tool for batch-level quality control.

AQX 1125 CoA mostly includes findings from lab analyses of a specific batch. For each AQX 1125 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

AQX 1125 may be tested according to a variety of international standards, such as European Pharmacopoeia (AQX 1125 EP), AQX 1125 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (AQX 1125 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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