Find Arbutamine Hydrochloride manufacturers, exporters & distributors on PharmaCompass

PharmaCompass

Synopsis

Related ProductsRelated Products

Synopsis

ACTIVE PHARMA INGREDIENTS

0

API Suppliers

API Suppliers

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

0

Listed Suppliers

Other Suppliers

API REF. PRICE (USD/KG)

$
$ 0

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Genesa, Arbutamine hcl, Arbutamine hydrochloride [usan], 125251-66-3, K0nf2cpj7f, Gp-2-121-3
Molecular Formula
C18H24ClNO4
Molecular Weight
353.8  g/mol
InChI Key
ATBUNPBAFFCFKY-FERBBOLQSA-N
FDA UNII
K0NF2CPJ7F

Arbutamine Hydrochloride
Arbutamine Hydrochloride is the hydrochloride salt form of arbutamine, a synthetic catecholamine with positive chronotropic and inotropic properties, used in echocardiography and diagnostic coronary angiography. Arbutamine binds to and activates beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and increasing force of myocardial contraction. By exerting a chronotropic and inotropic effect, arbutamine mimics the cardiac stress caused by exercise that may prevent adequate tissue perfusion and oxygenation, and may provoke myocardial ischemia in patients with coronary artery disease.
1 2D Structure

Arbutamine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[(1R)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride
2.1.2 InChI
InChI=1S/C18H23NO4.ClH/c20-15-7-4-13(5-8-15)3-1-2-10-19-12-18(23)14-6-9-16(21)17(22)11-14;/h4-9,11,18-23H,1-3,10,12H2;1H/t18-;/m0./s1
2.1.3 InChI Key
ATBUNPBAFFCFKY-FERBBOLQSA-N
2.1.4 Canonical SMILES
C1=CC(=CC=C1CCCCNCC(C2=CC(=C(C=C2)O)O)O)O.Cl
2.1.5 Isomeric SMILES
C1=CC(=CC=C1CCCCNC[C@@H](C2=CC(=C(C=C2)O)O)O)O.Cl
2.2 Other Identifiers
2.2.1 UNII
K0NF2CPJ7F
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Arbutamine

2. Arbutamine Hydrochloride, (r)-isomer

3. Genesa

2.3.2 Depositor-Supplied Synonyms

1. Genesa

2. Arbutamine Hcl

3. Arbutamine Hydrochloride [usan]

4. 125251-66-3

5. K0nf2cpj7f

6. Gp-2-121-3

7. (r)-3,4-dihydroxy-alpha-(((4-(p-hydroxyphenyl)butyl)amino)methyl)benzyl Alcohol Hydrochloride

8. Arbutamine (hydrochloride)

9. Arbutamine Hydrochloride (usan)

10. Unii-k0nf2cpj7f

11. Genesa (tn)

12. Schembl40757

13. Chembl1200385

14. Dtxsid40154718

15. Arbutamine Hydrochloride [mi]

16. Hy-16056a

17. 1,2-benzenediol, 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)-, (r)-hydrochloride

18. Arbutamine Hydrochloride [mart.]

19. Arbutamine Hydrochloride [vandf]

20. Arbutamine Hydrochloride [who-dd]

21. 1,2-benzenediol, 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)-, (r)-, Hydrochloride

22. Cs-0108214

23. Arbutamine Hydrochloride [orange Book]

24. D02976

25. Q27281787

26. 4-[(1r)-1-hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl]benzene-1,2-diol;hydrochloride

27. (r)-3,4-dihydroxy-.alpha.-(((4-(p-hydroxyphenyl)butyl)amino)methyl)benzyl Alcohol Hydrochloride

28. 1,2-benzenediol, 4-(1-hydroxy-2-((4-(4-hydroxyphenyl)butyl)amino)ethyl)-, (r) Hydrochloride

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 353.8 g/mol
Molecular Formula C18H24ClNO4
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count5
Rotatable Bond Count8
Exact Mass353.1393859 g/mol
Monoisotopic Mass353.1393859 g/mol
Topological Polar Surface Area93 Ų
Heavy Atom Count24
Formal Charge0
Complexity320
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adrenergic beta-Agonists

Drugs that selectively bind to and activate beta-adrenergic receptors. (See all compounds classified as Adrenergic beta-Agonists.)


Cardiotonic Agents

Agents that have a strengthening effect on the heart or that can increase cardiac output. They may be CARDIAC GLYCOSIDES; SYMPATHOMIMETICS; or other drugs. They are used after MYOCARDIAL INFARCT; CARDIAC SURGICAL PROCEDURES; in SHOCK; or in congestive heart failure (HEART FAILURE). (See all compounds classified as Cardiotonic Agents.)


ABOUT THIS PAGE

Looking for 125251-66-3 / Arbutamine Hydrochloride API manufacturers, exporters & distributors?

Arbutamine Hydrochloride manufacturers, exporters & distributors 1

82

PharmaCompass offers a list of Arbutamine Hydrochloride API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Arbutamine Hydrochloride manufacturer or Arbutamine Hydrochloride supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Arbutamine Hydrochloride manufacturer or Arbutamine Hydrochloride supplier.

PharmaCompass also assists you with knowing the Arbutamine Hydrochloride API Price utilized in the formulation of products. Arbutamine Hydrochloride API Price is not always fixed or binding as the Arbutamine Hydrochloride Price is obtained through a variety of data sources. The Arbutamine Hydrochloride Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Arbutamine Hydrochloride

Synonyms

Genesa, Arbutamine hcl, Arbutamine hydrochloride [usan], 125251-66-3, K0nf2cpj7f, Gp-2-121-3

Cas Number

125251-66-3

Unique Ingredient Identifier (UNII)

K0NF2CPJ7F

About Arbutamine Hydrochloride

Arbutamine Hydrochloride is the hydrochloride salt form of arbutamine, a synthetic catecholamine with positive chronotropic and inotropic properties, used in echocardiography and diagnostic coronary angiography. Arbutamine binds to and activates beta-1 adrenergic receptors in the myocardium, thereby increasing heart rate and increasing force of myocardial contraction. By exerting a chronotropic and inotropic effect, arbutamine mimics the cardiac stress caused by exercise that may prevent adequate tissue perfusion and oxygenation, and may provoke myocardial ischemia in patients with coronary artery disease.

Arbutamine Hydrochloride Manufacturers

A Arbutamine Hydrochloride manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Arbutamine Hydrochloride, including repackagers and relabelers. The FDA regulates Arbutamine Hydrochloride manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Arbutamine Hydrochloride API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Arbutamine Hydrochloride Suppliers

A Arbutamine Hydrochloride supplier is an individual or a company that provides Arbutamine Hydrochloride active pharmaceutical ingredient (API) or Arbutamine Hydrochloride finished formulations upon request. The Arbutamine Hydrochloride suppliers may include Arbutamine Hydrochloride API manufacturers, exporters, distributors and traders.

Arbutamine Hydrochloride GMP

Arbutamine Hydrochloride Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Arbutamine Hydrochloride GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Arbutamine Hydrochloride GMP manufacturer or Arbutamine Hydrochloride GMP API supplier for your needs.

Arbutamine Hydrochloride CoA

A Arbutamine Hydrochloride CoA (Certificate of Analysis) is a formal document that attests to Arbutamine Hydrochloride's compliance with Arbutamine Hydrochloride specifications and serves as a tool for batch-level quality control.

Arbutamine Hydrochloride CoA mostly includes findings from lab analyses of a specific batch. For each Arbutamine Hydrochloride CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Arbutamine Hydrochloride may be tested according to a variety of international standards, such as European Pharmacopoeia (Arbutamine Hydrochloride EP), Arbutamine Hydrochloride JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Arbutamine Hydrochloride USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty